CN103347880B - 用于控制无脊椎害虫的异噁唑啉衍生物 - Google Patents

用于控制无脊椎害虫的异噁唑啉衍生物 Download PDF

Info

Publication number
CN103347880B
CN103347880B CN201280008309.4A CN201280008309A CN103347880B CN 103347880 B CN103347880 B CN 103347880B CN 201280008309 A CN201280008309 A CN 201280008309A CN 103347880 B CN103347880 B CN 103347880B
Authority
CN
China
Prior art keywords
alkyl
formula
group
compound
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280008309.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN103347880A (zh
Inventor
N·高维里
S·南申
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elanco Tiergesundheit AG
Original Assignee
Novartis Tiergesundheit AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Tiergesundheit AG filed Critical Novartis Tiergesundheit AG
Publication of CN103347880A publication Critical patent/CN103347880A/zh
Application granted granted Critical
Publication of CN103347880B publication Critical patent/CN103347880B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201280008309.4A 2011-02-10 2012-02-09 用于控制无脊椎害虫的异噁唑啉衍生物 Expired - Fee Related CN103347880B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH2472011 2011-02-10
CH00247/2011 2011-02-10
PCT/EP2012/052241 WO2012107533A1 (en) 2011-02-10 2012-02-09 Isoxazoline derivatives for controlling invertebrate pests

Publications (2)

Publication Number Publication Date
CN103347880A CN103347880A (zh) 2013-10-09
CN103347880B true CN103347880B (zh) 2015-11-25

Family

ID=45607737

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280008309.4A Expired - Fee Related CN103347880B (zh) 2011-02-10 2012-02-09 用于控制无脊椎害虫的异噁唑啉衍生物

Country Status (15)

Country Link
US (2) US20130324538A1 (enExample)
EP (1) EP2673273A1 (enExample)
JP (1) JP2014505089A (enExample)
CN (1) CN103347880B (enExample)
AR (1) AR085354A1 (enExample)
AU (1) AU2012215440B2 (enExample)
BR (1) BR112013020520A2 (enExample)
CA (1) CA2826067A1 (enExample)
CL (1) CL2013002296A1 (enExample)
CO (1) CO6731114A2 (enExample)
MX (1) MX2013009211A (enExample)
RU (1) RU2013141413A (enExample)
TW (1) TWI511966B (enExample)
WO (1) WO2012107533A1 (enExample)
ZA (1) ZA201305226B (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY33403A (es) * 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales
AR086113A1 (es) * 2011-04-30 2013-11-20 Abbott Lab Isoxazolinas como agentes terapeuticos
WO2012155352A1 (en) * 2011-05-19 2012-11-22 Eli Lilly And Company Dihydroisoxazole compounds, parasiticidal uses and formulations thereof
HUE043949T2 (hu) 2012-02-06 2019-09-30 Boehringer Ingelheim Animal Health Usa Inc Szisztémásan ható hatóanyagokat tartalmazó, parazitaellenes, szájon át adagolt állatgyógyászati készítmények, eljárások és alkalmazásuk
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
KR102191469B1 (ko) 2013-02-06 2020-12-16 바이엘 애니멀 헬스 게엠베하 해충 방제제로서의 할로겐-치환된 피라졸 유도체
CA2916833A1 (en) 2013-06-24 2014-12-31 Basf Se Thiophene- or furan-substituted isothiazoline compounds as pesticides
US9447084B2 (en) 2013-11-01 2016-09-20 Merial, Inc. Antiparisitic and pesticidal isoxazoline compounds
PT4306168T (pt) 2013-12-20 2025-07-24 Intervet Int Bv Composições de isoxazolina e utilização das mesmas na prevenção ou tratamento de infestações parasitárias em animais
EP3878281B1 (en) 2013-12-20 2023-05-24 Intervet International B.V. Use of isoxazoline compounds in poultry
EP3089972B1 (de) 2014-01-03 2018-05-16 Bayer Animal Health GmbH Neue pyrazolyl-heteroarylamide als schädlingsbekämpfungsmittel
CN106455560B (zh) 2014-04-17 2020-12-22 勃林格殷格翰动物保健美国公司 用于保护动物免受寄生物的丙二腈化合物的用途
WO2016008830A1 (de) 2014-07-15 2016-01-21 Bayer Cropscience Aktiengesellschaft Aryl-triazolyl-pyridine als schädlingsbekämpfungsmittel
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
PY1609250A (es) 2015-02-26 2018-03-01 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
SG11201708068PA (en) * 2015-04-08 2017-10-30 Merial Inc Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
CN114891070A (zh) 2015-05-20 2022-08-12 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
UY40429A (es) 2016-02-24 2023-10-13 Boehringer Ingelheim Animal Health Usa Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
EP3497101B1 (de) * 2016-08-10 2020-12-30 Bayer CropScience Aktiengesellschaft Substituierte 2-heterocyclyl-imidazolyl-carboxamide als schädlingsbekämpfungsmittel
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
MX2019005628A (es) 2016-11-16 2019-12-18 Boehringer Ingelheim Animal Health Usa Inc Compuestos depsipeptidos antihelminticos.
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
ES2944616T3 (es) 2017-08-14 2023-06-22 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas
KR20250057155A (ko) 2017-12-15 2025-04-28 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
TWI812673B (zh) * 2018-02-12 2023-08-21 美商富曼西公司 用於防治無脊椎害蟲之萘異噁唑啉化合物
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
US12030875B2 (en) 2018-09-07 2024-07-09 PIC Therapeutics, Inc. EIF4E inhibitors and uses thereof
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
BR112021018631A2 (pt) 2019-03-19 2021-11-23 Boehringer Ingelheim Animal Health Usa Inc Compostos anti-helmínticos de aza-benzotiofeno e aza-benzofurano
US12502377B2 (en) 2019-04-04 2025-12-23 Tarsus Pharmaceuticals, Inc. Method of eradicating ticks that attach to humans using lotilaner formulations
US20220249445A1 (en) * 2019-06-19 2022-08-11 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
EP3986377A4 (en) * 2019-06-19 2023-07-19 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
CN115190794B (zh) * 2020-01-29 2026-03-20 礼蓝动物保健有限公司 用于防治非人类生物体上的寄生虫的药物组合物
AU2021230289A1 (en) 2020-03-03 2022-09-29 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof
WO2021242581A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
JP7824305B2 (ja) 2021-01-27 2026-03-04 コルテバ アグリサイエンス エルエルシー 魚における寄生生物に対するシクロプロピルアミド化合物
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
CN118019739A (zh) 2021-08-25 2024-05-10 皮克医疗公司 Eif4e抑制剂及其用途
JP2024534127A (ja) 2021-08-25 2024-09-18 ピク セラピューティクス, インコーポレイテッド eIF4E阻害剤及びその使用
UY39995A (es) 2021-11-01 2023-05-15 Boehringer Ingelheim Vetmedica GmbH Compuestos de pirrolopiridazina como antihelmínticos
JP2025507585A (ja) 2022-02-17 2025-03-21 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 流体製品メーラーを提供する方法及びシステム
CN114853748A (zh) * 2022-05-06 2022-08-05 武汉工程大学 一种含三氟甲烷异噁唑啉类衍生物、其制备方法和应用
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059072A (zh) * 1990-08-17 1992-03-04 赫彻斯特股份公司 含异唑啉或异噻唑啉的植物保护制剂和新的异唑啉类和异噻唑啉类化合物
CN1133038A (zh) * 1993-09-16 1996-10-09 赫彻斯特-舍林农业发展有限公司 取代异噁唑啉及其制备方法,含有它们的试剂及其作为防护剂的用途
WO2001007422A1 (de) * 1999-07-27 2001-02-01 Aventis Cropscience Gmbh Isoxazolyl- und isoxazolinyl-substituierte benzoylcyclohexandione, verfahren zu ihrer herstellung und ihre verwendung als herbizide und pflanzenwachstumsregulatoren
WO2007075459A2 (en) * 2005-12-16 2007-07-05 E. I. Du Pont De Nemours And Company 5-aryl isoxazolines for controlling invertebrate pests
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100606083B1 (ko) 2004-11-04 2006-07-31 삼성전자주식회사 광대역 무선 접속 통신 시스템에서 부채널 할당 시스템 및 방법
ES2443690T3 (es) * 2005-09-02 2014-02-20 Nissan Chemical Industries, Ltd. Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備4-乙醯基-n-〔2-側氧基-2-〔(2,2,2-三氟乙基)胺基〕乙基〕-1-萘甲醯胺之化合物及方法
WO2009071500A2 (en) 2007-12-03 2009-06-11 Novartis Ag Organic compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059072A (zh) * 1990-08-17 1992-03-04 赫彻斯特股份公司 含异唑啉或异噻唑啉的植物保护制剂和新的异唑啉类和异噻唑啉类化合物
CN1133038A (zh) * 1993-09-16 1996-10-09 赫彻斯特-舍林农业发展有限公司 取代异噁唑啉及其制备方法,含有它们的试剂及其作为防护剂的用途
WO2001007422A1 (de) * 1999-07-27 2001-02-01 Aventis Cropscience Gmbh Isoxazolyl- und isoxazolinyl-substituierte benzoylcyclohexandione, verfahren zu ihrer herstellung und ihre verwendung als herbizide und pflanzenwachstumsregulatoren
WO2007075459A2 (en) * 2005-12-16 2007-07-05 E. I. Du Pont De Nemours And Company 5-aryl isoxazolines for controlling invertebrate pests
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
具有除草活性的异恶唑啉类化合物的研究进展;范玉杰等;《农药研究与应用》;20101031;第14卷(第5期);第1-5页 *

Also Published As

Publication number Publication date
US20130324538A1 (en) 2013-12-05
AU2012215440A1 (en) 2013-08-01
RU2013141413A (ru) 2015-03-20
US20160024062A1 (en) 2016-01-28
EP2673273A1 (en) 2013-12-18
WO2012107533A1 (en) 2012-08-16
TWI511966B (zh) 2015-12-11
AR085354A1 (es) 2013-09-25
NZ613191A (en) 2015-06-26
CL2013002296A1 (es) 2014-03-14
MX2013009211A (es) 2013-08-29
CA2826067A1 (en) 2012-08-16
CO6731114A2 (es) 2013-08-15
TW201309683A (zh) 2013-03-01
JP2014505089A (ja) 2014-02-27
ZA201305226B (en) 2014-03-26
CN103347880A (zh) 2013-10-09
BR112013020520A2 (pt) 2016-07-12
AU2012215440B2 (en) 2015-08-27

Similar Documents

Publication Publication Date Title
CN103347880B (zh) 用于控制无脊椎害虫的异噁唑啉衍生物
CN102947296B (zh) 用于防治害虫的5-芳基异噁唑啉
US8383659B2 (en) Isoxazoline derivatives as pesticides
EP2683713B1 (en) Isoxazole derivatives
US9491941B2 (en) (Hetero) arylacrylamides for the control of ectoparasites

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: SWISS NOVARTIS ANIMAL HEALTH CO., LTD.

Free format text: FORMER OWNER: NOVARTIS AG

Effective date: 20150420

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20150420

Address after: Basel

Applicant after: Animal health company limited of Novartis of Switzerland

Address before: Basel

Applicant before: Novartis AG

C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20151125

Termination date: 20160209

CF01 Termination of patent right due to non-payment of annual fee