JP2014502988A5 - - Google Patents
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- Publication number
- JP2014502988A5 JP2014502988A5 JP2013549825A JP2013549825A JP2014502988A5 JP 2014502988 A5 JP2014502988 A5 JP 2014502988A5 JP 2013549825 A JP2013549825 A JP 2013549825A JP 2013549825 A JP2013549825 A JP 2013549825A JP 2014502988 A5 JP2014502988 A5 JP 2014502988A5
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- JP
- Japan
- Prior art keywords
- alkyl
- ring
- group
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- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11151688.6 | 2011-01-21 | ||
| EP11151688 | 2011-01-21 | ||
| EP11191903 | 2011-12-05 | ||
| EP11191903.1 | 2011-12-05 | ||
| PCT/EP2012/050841 WO2012098217A1 (en) | 2011-01-21 | 2012-01-20 | Fused dihydrofurans as gpr119 modulators for the treatment of diabetes, obesity and related disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014502988A JP2014502988A (ja) | 2014-02-06 |
| JP2014502988A5 true JP2014502988A5 (enExample) | 2014-03-20 |
| JP5703393B2 JP5703393B2 (ja) | 2015-04-15 |
Family
ID=45495952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549825A Active JP5703393B2 (ja) | 2011-01-21 | 2012-01-20 | 糖尿病、肥満および関連障害の治療のためのｇｐｒ１１９モジュレーターとしての縮合ジヒドロフラン |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8778926B2 (enExample) |
| EP (1) | EP2665719B1 (enExample) |
| JP (1) | JP5703393B2 (enExample) |
| KR (1) | KR20140003496A (enExample) |
| CN (1) | CN103443097A (enExample) |
| AP (1) | AP2013006985A0 (enExample) |
| AR (1) | AR084905A1 (enExample) |
| AU (1) | AU2012208530A1 (enExample) |
| BR (1) | BR112013017669A2 (enExample) |
| CA (1) | CA2825124A1 (enExample) |
| CO (1) | CO6781501A2 (enExample) |
| EA (1) | EA201300846A1 (enExample) |
| EC (1) | ECSP13012800A (enExample) |
| MA (1) | MA34839B1 (enExample) |
| MX (1) | MX2013008083A (enExample) |
| PH (1) | PH12013501515A1 (enExample) |
| SG (1) | SG192036A1 (enExample) |
| UY (1) | UY33871A (enExample) |
| WO (1) | WO2012098217A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201113269A (en) | 2009-06-24 | 2011-04-16 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
| UY33805A (es) | 2010-12-17 | 2012-07-31 | Boehringer Ingelheim Int | ?Derivados de dihidrobenzofuranil-piperidinilo, aza-dihidrobenzofuranilpiperidinilo y diaza-dihidrobenzofuranil-piperidinilo, composiciones farmacéuticas que los contienen y usos de los mismos?. |
| WO2012123449A1 (en) | 2011-03-14 | 2012-09-20 | Boehringer Ingelheim International Gmbh | N- cyclopropyl - n- piperidinylbenzamides as gpr119 modulators |
| JP6094578B2 (ja) | 2011-06-09 | 2017-03-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝性障害の治療のためのｇｐｒ１１９モジュレーターとしての置換ピペリジン |
| US8853239B2 (en) | 2011-12-09 | 2014-10-07 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| US9012456B2 (en) * | 2012-02-28 | 2015-04-21 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| WO2013167514A1 (en) * | 2012-05-07 | 2013-11-14 | Boehringer Ingelheim International Gmbh | New 2,3-dihydro-furo[2,3-c]pyridines, their use as modulators of the g-protein-coupled receptor gpr119 and pharmaceutical compositions comprising them |
| EP2872127A1 (en) | 2012-07-11 | 2015-05-20 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| US10954229B2 (en) | 2016-04-08 | 2021-03-23 | Mankind Pharma Ltd. | GPR119 agonist compounds |
| US10526345B2 (en) | 2016-04-08 | 2020-01-07 | Mankind Pharma Ltd. | Compounds as GPR119 agonists |
| US10208030B2 (en) * | 2016-04-08 | 2019-02-19 | Mankind Pharma Ltd. | GPR119 agonist compounds |
| JP7095288B2 (ja) * | 2018-01-24 | 2022-07-05 | 富士フイルムビジネスイノベーション株式会社 | 定着装置および画像形成装置 |
| CN115667277A (zh) | 2020-02-28 | 2023-01-31 | 卡尔优普公司 | Gpr40激动剂 |
| CA3178994A1 (en) | 2020-05-19 | 2021-11-25 | Iyassu Sebhat | Ampk activators |
| AU2021297323A1 (en) | 2020-06-26 | 2023-02-16 | Kallyope, Inc. | AMPK activators |
| WO2025037213A1 (en) * | 2023-08-11 | 2025-02-20 | Mankind Pharma Ltd. | Pharmaceutical formulations of gpr119 agonists and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003221386A (ja) * | 2001-11-26 | 2003-08-05 | Takeda Chem Ind Ltd | 二環性誘導体、その製造法およびその用途 |
| US20090221644A1 (en) * | 2005-06-30 | 2009-09-03 | Stuart Edward Bradley | Gpcr Agonists |
| AR064416A1 (es) * | 2006-12-21 | 2009-04-01 | Cancer Rec Tech Ltd | Derivados de purina, piridina y pirimidina condensadas con heterociclos, moduladores de pka y/o pkb, composiciones farmaceuticas que los contienen, y usos para el tratamiento de enfermedades hiperproliferativas. |
| TW201031668A (en) * | 2009-01-22 | 2010-09-01 | Mitsubishi Tanabe Pharma Corp | Novel pyrrolo[2,3-d] pyrimidine compound |
| TW201113269A (en) | 2009-06-24 | 2011-04-16 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
| TW201111361A (en) | 2009-06-24 | 2011-04-01 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
| US8431595B2 (en) * | 2009-08-20 | 2013-04-30 | The University Of Tennessee Research Foundation | Furanopyridine cannabinoid compounds and related methods of use |
| WO2011140161A1 (en) * | 2010-05-06 | 2011-11-10 | Bristol-Myers Squibb Company | Benzofuranyl analogues as gpr119 modulators |
| US8940716B2 (en) * | 2010-05-06 | 2015-01-27 | Bristol-Myers Squibb Company | Bicyclic heteroaryl compounds as GPR119 modulators |
| EP2566864B1 (en) | 2010-05-07 | 2014-09-03 | Boehringer Ingelheim International GmbH | Pyridazinones as gpr119 agonists |
| UY33805A (es) * | 2010-12-17 | 2012-07-31 | Boehringer Ingelheim Int | ?Derivados de dihidrobenzofuranil-piperidinilo, aza-dihidrobenzofuranilpiperidinilo y diaza-dihidrobenzofuranil-piperidinilo, composiciones farmacéuticas que los contienen y usos de los mismos?. |
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2012
- 2012-01-20 MX MX2013008083A patent/MX2013008083A/es not_active Application Discontinuation
- 2012-01-20 SG SG2013055066A patent/SG192036A1/en unknown
- 2012-01-20 AR ARP120100198A patent/AR084905A1/es unknown
- 2012-01-20 JP JP2013549825A patent/JP5703393B2/ja active Active
- 2012-01-20 BR BR112013017669A patent/BR112013017669A2/pt not_active Application Discontinuation
- 2012-01-20 KR KR1020137019225A patent/KR20140003496A/ko not_active Withdrawn
- 2012-01-20 WO PCT/EP2012/050841 patent/WO2012098217A1/en not_active Ceased
- 2012-01-20 AU AU2012208530A patent/AU2012208530A1/en not_active Abandoned
- 2012-01-20 CN CN2012800140275A patent/CN103443097A/zh active Pending
- 2012-01-20 AP AP2013006985A patent/AP2013006985A0/xx unknown
- 2012-01-20 UY UY0001033871A patent/UY33871A/es unknown
- 2012-01-20 MA MA36131A patent/MA34839B1/fr unknown
- 2012-01-20 US US13/354,356 patent/US8778926B2/en active Active
- 2012-01-20 EP EP12700413.3A patent/EP2665719B1/en active Active
- 2012-01-20 EA EA201300846A patent/EA201300846A1/ru unknown
- 2012-01-20 CA CA2825124A patent/CA2825124A1/en not_active Abandoned
- 2012-01-20 PH PH1/2013/501515A patent/PH12013501515A1/en unknown
-
2013
- 2013-07-26 CO CO13177678A patent/CO6781501A2/es not_active Application Discontinuation
- 2013-07-29 EC ECSP13012800 patent/ECSP13012800A/es unknown