RU2012121096A - Биомаркер меланомы - Google Patents
Биомаркер меланомы Download PDFInfo
- Publication number
- RU2012121096A RU2012121096A RU2012121096/10A RU2012121096A RU2012121096A RU 2012121096 A RU2012121096 A RU 2012121096A RU 2012121096/10 A RU2012121096/10 A RU 2012121096/10A RU 2012121096 A RU2012121096 A RU 2012121096A RU 2012121096 A RU2012121096 A RU 2012121096A
- Authority
- RU
- Russia
- Prior art keywords
- melanoma
- biomarker
- patient
- fragment
- nucleic acid
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title claims abstract 37
- 201000001441 melanoma Diseases 0.000 title claims abstract 37
- 239000012634 fragment Substances 0.000 claims abstract 17
- 150000007523 nucleic acids Chemical group 0.000 claims abstract 17
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract 10
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims abstract 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract 8
- 150000001413 amino acids Chemical class 0.000 claims abstract 7
- 108020004707 nucleic acids Proteins 0.000 claims abstract 4
- 102000039446 nucleic acids Human genes 0.000 claims abstract 4
- 238000000034 method Methods 0.000 claims 19
- 239000000523 sample Substances 0.000 claims 12
- 239000013060 biological fluid Substances 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 239000013068 control sample Substances 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 230000001926 lymphatic effect Effects 0.000 claims 3
- 210000002381 plasma Anatomy 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000002254 cytotoxic agent Substances 0.000 claims 1
- 231100000599 cytotoxic agent Toxicity 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0921329.9 | 2009-12-04 | ||
| GBGB0921329.9A GB0921329D0 (en) | 2009-12-04 | 2009-12-04 | Biomarker |
| PCT/GB2010/001334 WO2011067549A1 (en) | 2009-12-04 | 2010-07-13 | Melanoma specific biomarker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012121096A true RU2012121096A (ru) | 2014-01-10 |
Family
ID=41641989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012121096/10A RU2012121096A (ru) | 2009-12-04 | 2010-07-13 | Биомаркер меланомы |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120263654A1 (enExample) |
| EP (1) | EP2507384A1 (enExample) |
| JP (1) | JP2013512668A (enExample) |
| CN (1) | CN102791878A (enExample) |
| AU (1) | AU2010326433A1 (enExample) |
| BR (1) | BR112012013041A2 (enExample) |
| CA (1) | CA2782034A1 (enExample) |
| GB (1) | GB0921329D0 (enExample) |
| IL (1) | IL219834A0 (enExample) |
| IN (1) | IN2012DN04381A (enExample) |
| MX (1) | MX2012006229A (enExample) |
| RU (1) | RU2012121096A (enExample) |
| WO (1) | WO2011067549A1 (enExample) |
| ZA (1) | ZA201203517B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2294216A4 (en) | 2008-05-14 | 2011-11-23 | Dermtech Int | DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY ANALYSIS OF NUCLEIC ACIDS |
| US20150005184A1 (en) * | 2013-06-28 | 2015-01-01 | Dermtech International | Diagnosis of melanoma by nucleic acid analysis |
| US11578373B2 (en) | 2019-03-26 | 2023-02-14 | Dermtech, Inc. | Gene classifiers and uses thereof in skin cancers |
| WO2016168174A1 (en) * | 2015-04-13 | 2016-10-20 | The Translational Genomics Research Institute | Predicting the occurrence of metastatic cancer using epigenomic biomarkers and non-invasive methodologies |
| JP2018518203A (ja) * | 2015-06-24 | 2018-07-12 | オックスフォード バイオダイナミックス リミテッド | エピジェネティックな染色体相互作用 |
| KR101777085B1 (ko) * | 2017-02-23 | 2017-09-11 | 주식회사 성균바이오텍 | En2 단백질의 면역원성 단편 펩타이드 또는 이를 특이적으로 인식하는 항체 조성물 |
| US11976332B2 (en) | 2018-02-14 | 2024-05-07 | Dermtech, Inc. | Gene classifiers and uses thereof in non-melanoma skin cancers |
| RU2766739C1 (ru) * | 2021-04-12 | 2022-03-15 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Способ прогноза эффективности терапии меланомы |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2469089A1 (en) * | 2003-07-08 | 2005-01-08 | Institut De Recherches Cliniques De Montreal | En-2 gene, disgnostic and therapeutic uses thereof |
| US20070154889A1 (en) * | 2004-06-25 | 2007-07-05 | Veridex, Llc | Methods and reagents for the detection of melanoma |
| US7615349B2 (en) * | 2006-09-07 | 2009-11-10 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Melanoma gene signature |
| US7960110B2 (en) * | 2006-11-15 | 2011-06-14 | The Regents Of The University Of California | Detection of chromosomal region copy number changes to diagnose melanoma |
| GB0625321D0 (en) * | 2006-12-19 | 2007-01-24 | Univ Surrey | Cancer biomarker |
| WO2009131733A1 (en) * | 2008-04-21 | 2009-10-29 | The Trustees Of Columbia University In The City Of New York | Gab2 amplification in melanoma |
-
2009
- 2009-12-04 GB GBGB0921329.9A patent/GB0921329D0/en not_active Ceased
-
2010
- 2010-07-13 CN CN2010800550196A patent/CN102791878A/zh active Pending
- 2010-07-13 WO PCT/GB2010/001334 patent/WO2011067549A1/en not_active Ceased
- 2010-07-13 CA CA2782034A patent/CA2782034A1/en not_active Abandoned
- 2010-07-13 US US13/513,345 patent/US20120263654A1/en not_active Abandoned
- 2010-07-13 IN IN4381DEN2012 patent/IN2012DN04381A/en unknown
- 2010-07-13 JP JP2012541569A patent/JP2013512668A/ja active Pending
- 2010-07-13 MX MX2012006229A patent/MX2012006229A/es not_active Application Discontinuation
- 2010-07-13 RU RU2012121096/10A patent/RU2012121096A/ru not_active Application Discontinuation
- 2010-07-13 AU AU2010326433A patent/AU2010326433A1/en not_active Abandoned
- 2010-07-13 BR BR112012013041A patent/BR112012013041A2/pt not_active IP Right Cessation
- 2010-07-13 EP EP10742865A patent/EP2507384A1/en not_active Withdrawn
-
2012
- 2012-05-15 ZA ZA2012/03517A patent/ZA201203517B/en unknown
- 2012-05-16 IL IL219834A patent/IL219834A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012013041A2 (pt) | 2016-10-11 |
| CA2782034A1 (en) | 2011-06-09 |
| WO2011067549A1 (en) | 2011-06-09 |
| JP2013512668A (ja) | 2013-04-18 |
| AU2010326433A1 (en) | 2012-06-07 |
| ZA201203517B (en) | 2013-02-27 |
| US20120263654A1 (en) | 2012-10-18 |
| MX2012006229A (es) | 2012-06-19 |
| GB0921329D0 (en) | 2010-01-20 |
| IL219834A0 (en) | 2012-07-31 |
| EP2507384A1 (en) | 2012-10-10 |
| CN102791878A (zh) | 2012-11-21 |
| IN2012DN04381A (enExample) | 2015-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20140901 |