RU2010138612A - ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ C5аR - Google Patents

ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ C5аR Download PDF

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Publication number
RU2010138612A
RU2010138612A RU2010138612/10A RU2010138612A RU2010138612A RU 2010138612 A RU2010138612 A RU 2010138612A RU 2010138612/10 A RU2010138612/10 A RU 2010138612/10A RU 2010138612 A RU2010138612 A RU 2010138612A RU 2010138612 A RU2010138612 A RU 2010138612A
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RU
Russia
Prior art keywords
seq
amino acid
acid sequence
region containing
variable region
Prior art date
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RU2010138612/10A
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English (en)
Russian (ru)
Inventor
Питер УИТФЕЛЬД (AU)
Питер УИТФЕЛЬД
Дэвид ЗАХРА (AU)
Дэвид ЗАХРА
Чарльз МАККЕЙ (AU)
Чарльз МАККЕЙ
Original Assignee
Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД (AU)
Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД
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Publication of RU2010138612A publication Critical patent/RU2010138612A/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2010138612/10A 2008-02-20 2009-02-19 ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ C5аR RU2010138612A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6653908P 2008-02-20 2008-02-20
US61/066,539 2008-02-20

Publications (1)

Publication Number Publication Date
RU2010138612A true RU2010138612A (ru) 2012-03-27

Family

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Family Applications (1)

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RU2010138612/10A RU2010138612A (ru) 2008-02-20 2009-02-19 ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ C5аR

Country Status (14)

Country Link
US (3) US8268972B2 (https=)
EP (2) EP2254911B1 (https=)
JP (2) JP2011515073A (https=)
KR (1) KR20100117120A (https=)
CN (2) CN101970494B (https=)
AU (1) AU2009217224B2 (https=)
BR (1) BRPI0907532A2 (https=)
CA (1) CA2714296A1 (https=)
ES (1) ES2562627T3 (https=)
IL (1) IL207217A (https=)
MX (1) MX2010009190A (https=)
RU (1) RU2010138612A (https=)
WO (1) WO2009103113A1 (https=)
ZA (1) ZA201005348B (https=)

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Also Published As

Publication number Publication date
EP2254911A4 (en) 2011-10-19
CN104193824A (zh) 2014-12-10
IL207217A (en) 2015-03-31
EP2254911B1 (en) 2015-11-25
US20130129721A1 (en) 2013-05-23
ZA201005348B (en) 2011-10-26
CN101970494A (zh) 2011-02-09
JP6034826B2 (ja) 2016-11-30
US20110190477A1 (en) 2011-08-04
US8808701B2 (en) 2014-08-19
WO2009103113A1 (en) 2009-08-27
US8361468B2 (en) 2013-01-29
BRPI0907532A2 (pt) 2015-07-28
KR20100117120A (ko) 2010-11-02
AU2009217224A1 (en) 2009-08-27
US8268972B2 (en) 2012-09-18
ES2562627T3 (es) 2016-03-07
IL207217A0 (en) 2010-12-30
EP2826791A2 (en) 2015-01-21
MX2010009190A (es) 2010-09-10
EP2826791A3 (en) 2015-07-29
CA2714296A1 (en) 2009-08-27
JP2014193164A (ja) 2014-10-09
US20120315275A1 (en) 2012-12-13
JP2011515073A (ja) 2011-05-19
CN101970494B (zh) 2015-01-21
AU2009217224B2 (en) 2014-09-11
EP2254911A1 (en) 2010-12-01

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