RU2008147885A - Биосовместимая трехмерная матрица для иммобилизации биологических веществ - Google Patents
Биосовместимая трехмерная матрица для иммобилизации биологических веществ Download PDFInfo
- Publication number
- RU2008147885A RU2008147885A RU2008147885/13A RU2008147885A RU2008147885A RU 2008147885 A RU2008147885 A RU 2008147885A RU 2008147885/13 A RU2008147885/13 A RU 2008147885/13A RU 2008147885 A RU2008147885 A RU 2008147885A RU 2008147885 A RU2008147885 A RU 2008147885A
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- RU
- Russia
- Prior art keywords
- carrier
- group
- stage
- fragments
- aqueous solution
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims 5
- 239000011159 matrix material Substances 0.000 title claims 2
- 238000000034 method Methods 0.000 claims abstract 40
- 239000007787 solid Substances 0.000 claims abstract 15
- 239000012620 biological material Substances 0.000 claims abstract 14
- 239000000203 mixture Substances 0.000 claims abstract 8
- 239000008280 blood Substances 0.000 claims abstract 6
- 210000004369 blood Anatomy 0.000 claims abstract 6
- 201000010099 disease Diseases 0.000 claims abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 4
- 238000001914 filtration Methods 0.000 claims abstract 2
- 229940127554 medical product Drugs 0.000 claims abstract 2
- 239000007864 aqueous solution Substances 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 13
- 239000000243 solution Substances 0.000 claims 11
- 239000012876 carrier material Substances 0.000 claims 10
- 229920001223 polyethylene glycol Polymers 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 239000000463 material Substances 0.000 claims 9
- 229920001612 Hydroxyethyl starch Polymers 0.000 claims 8
- 229940050526 hydroxyethylstarch Drugs 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 241000203069 Archaea Species 0.000 claims 6
- 241000894006 Bacteria Species 0.000 claims 6
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 6
- 229930195725 Mannitol Natural products 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 6
- 210000003527 eukaryotic cell Anatomy 0.000 claims 6
- 239000011521 glass Substances 0.000 claims 6
- 239000000594 mannitol Substances 0.000 claims 6
- 235000010355 mannitol Nutrition 0.000 claims 6
- -1 polyethylene Polymers 0.000 claims 6
- 102000009027 Albumins Human genes 0.000 claims 5
- 108010088751 Albumins Proteins 0.000 claims 5
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 5
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 5
- 210000004880 lymph fluid Anatomy 0.000 claims 5
- 229910000077 silane Inorganic materials 0.000 claims 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 241000243142 Porifera Species 0.000 claims 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 4
- 239000007789 gas Substances 0.000 claims 4
- 150000004676 glycans Chemical class 0.000 claims 4
- 229920003023 plastic Polymers 0.000 claims 4
- 239000004033 plastic Substances 0.000 claims 4
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims 4
- 239000004926 polymethyl methacrylate Substances 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 229920001282 polysaccharide Polymers 0.000 claims 4
- 239000005017 polysaccharide Substances 0.000 claims 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 229920002472 Starch Polymers 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 230000005855 radiation Effects 0.000 claims 3
- 239000000600 sorbitol Substances 0.000 claims 3
- 235000019698 starch Nutrition 0.000 claims 3
- 239000008107 starch Substances 0.000 claims 3
- 230000001954 sterilising effect Effects 0.000 claims 3
- 235000000346 sugar Nutrition 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- 239000004952 Polyamide Substances 0.000 claims 2
- 239000004698 Polyethylene Substances 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 229910004298 SiO 2 Inorganic materials 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- 239000006260 foam Substances 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 239000012510 hollow fiber Substances 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 150000001282 organosilanes Chemical class 0.000 claims 2
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 claims 2
- 238000012856 packing Methods 0.000 claims 2
- 244000052769 pathogen Species 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 235000021317 phosphate Nutrition 0.000 claims 2
- 229920002492 poly(sulfone) Polymers 0.000 claims 2
- 229920002239 polyacrylonitrile Polymers 0.000 claims 2
- 229920002647 polyamide Polymers 0.000 claims 2
- 229920000728 polyester Polymers 0.000 claims 2
- 229920000573 polyethylene Polymers 0.000 claims 2
- 229920001155 polypropylene Polymers 0.000 claims 2
- 229920002635 polyurethane Polymers 0.000 claims 2
- 239000004814 polyurethane Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 150000004756 silanes Chemical class 0.000 claims 2
- 238000004659 sterilization and disinfection Methods 0.000 claims 2
- 102000002322 Egg Proteins Human genes 0.000 claims 1
- 108010000912 Egg Proteins Proteins 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 235000021307 Triticum Nutrition 0.000 claims 1
- 241000209140 Triticum Species 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 239000002981 blocking agent Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims 1
- 239000011363 dried mixture Substances 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- 229920005862 polyol Polymers 0.000 claims 1
- 150000003077 polyols Chemical class 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 150000005846 sugar alcohols Polymers 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 238000010189 synthetic method Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 238000004140 cleaning Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 210000002751 lymph Anatomy 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06009343.2 | 2006-05-05 | ||
| EP06009343A EP1852443A1 (en) | 2006-05-05 | 2006-05-05 | Biocompatible three dimensional matrix for the immobilization of biological substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008147885A true RU2008147885A (ru) | 2010-06-10 |
Family
ID=36975295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008147885/13A RU2008147885A (ru) | 2006-05-05 | 2007-05-07 | Биосовместимая трехмерная матрица для иммобилизации биологических веществ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9926383B2 (enExample) |
| EP (2) | EP1852443A1 (enExample) |
| JP (2) | JP5869201B2 (enExample) |
| CN (1) | CN101437853B (enExample) |
| AT (1) | ATE525402T1 (enExample) |
| BR (1) | BRPI0710920A2 (enExample) |
| RU (1) | RU2008147885A (enExample) |
| WO (1) | WO2007128550A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2058335B1 (en) * | 2007-11-07 | 2020-06-24 | Leukocare Ag | Biocompatible three dimensional matrix for the immobilization of biological substances |
| EP2236520A1 (en) * | 2009-03-31 | 2010-10-06 | Leukocare Ag | Stabilizing composition for immobilized biomolecules |
| EP2236617A1 (en) | 2009-03-31 | 2010-10-06 | Leukocare Ag | Methods of terminal sterilization of biofunctional compositions |
| CA2765540A1 (en) | 2009-06-17 | 2010-12-23 | Gilupi Gmbh | Detection device for in vivo and/or in vitro enrichment of sample material |
| EP2539435A2 (en) | 2010-02-23 | 2013-01-02 | Corning Incorporated | Modified substrates for protection of peptide-immobilized surfaces from gamma radiation degradation |
| AU2010202125B1 (en) * | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
| TWI546122B (zh) * | 2011-02-25 | 2016-08-21 | 東麗股份有限公司 | 血液成分吸附用載體及血液成分吸附管柱 |
| JP2018128408A (ja) * | 2017-02-10 | 2018-08-16 | 東ソー株式会社 | 抗体凝集体形成予測方法 |
| US20230041240A1 (en) | 2020-01-30 | 2023-02-09 | Leukocare Ag | Reduction of Adsorption |
| CN111420119A (zh) * | 2020-04-16 | 2020-07-17 | 南通大学 | 促进神经再生的活性多肽在材料表面共价接枝的方法及其应用 |
| CN113201528A (zh) * | 2021-05-28 | 2021-08-03 | 南京工业大学 | 一种表面改性材料及其制备方法和在酵母细胞吸附与聚集生长中的应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6187700A (ja) | 1984-10-05 | 1986-05-06 | Shimadzu Corp | ペプチド含有物質固定化物 |
| CH663728A5 (fr) | 1985-06-10 | 1988-01-15 | Battelle Memorial Institute | Procede de purification de substances bioactives par adsorption biospecifique. |
| JPS63230088A (ja) | 1987-03-19 | 1988-09-26 | Ngk Insulators Ltd | 微生物固定化用担体 |
| JP2641236B2 (ja) | 1988-03-09 | 1997-08-13 | 雪印乳業株式会社 | 固定化生体触媒の殺菌方法及び流動槽付反応器 |
| JPH07117519B2 (ja) | 1988-03-19 | 1995-12-18 | 株式会社堀場製作所 | 酵素固定膜の調製方法 |
| JPH01317389A (ja) | 1988-06-17 | 1989-12-22 | Tosoh Corp | 生化学反応用担体およびその製造方法 |
| US5077210A (en) * | 1989-01-13 | 1991-12-31 | Eigler Frances S | Immobilization of active agents on substrates with a silane and heterobifunctional crosslinking agent |
| US5283034A (en) * | 1989-06-29 | 1994-02-01 | Applied Immune Sciences, Inc. | Stabilization of sterilized surfaces for research and medical use |
| DE4005927A1 (de) * | 1990-02-25 | 1991-08-29 | Roehm Gmbh | Immobilisierung von proteinen an traegern |
| JPH0419561A (ja) | 1990-05-14 | 1992-01-23 | Nippon Shokubai Co Ltd | 免疫アッセイ用ブロッキング剤 |
| JP2813837B2 (ja) | 1990-09-07 | 1998-10-22 | 雪印乳業株式会社 | 高圧を利用した固定化酵素の殺菌方法 |
| JP2832760B2 (ja) | 1990-09-07 | 1998-12-09 | 雪印乳業株式会社 | 固定化酵素の殺菌方法 |
| JPH05219952A (ja) | 1992-02-14 | 1993-08-31 | Tdk Corp | 酵素固定用担体 |
| US5674292A (en) | 1995-06-07 | 1997-10-07 | Stryker Corporation | Terminally sterilized osteogenic devices and preparation thereof |
| US5691152A (en) * | 1995-11-09 | 1997-11-25 | E. R. Squibb & Sons, Inc. | Stable avidin composition |
| US6551794B1 (en) | 1995-11-09 | 2003-04-22 | E. R. Squibb & Sons, Inc. | Stable biotinylated biomolecule composition |
| US5730933A (en) * | 1996-04-16 | 1998-03-24 | Depuy Orthopaedics, Inc. | Radiation sterilization of biologically active compounds |
| US5760130A (en) * | 1997-05-13 | 1998-06-02 | Molecular Dynamics, Inc. | Aminosilane/carbodiimide coupling of DNA to glass substrate |
| JP3061598B2 (ja) | 1997-09-09 | 2000-07-10 | 高橋金物株式会社 | 戸当たり構造 |
| US6635269B1 (en) | 1997-11-24 | 2003-10-21 | Morphoplant Gmbh | Immobilizing mediator molecules via anchor molecules on metallic implant materials containing oxide layer |
| JP4252123B2 (ja) | 1998-04-23 | 2009-04-08 | ユニチカ株式会社 | 固定化線維素溶解活性酵素の活性安定化法 |
| DE19929787A1 (de) | 1999-06-29 | 2001-01-04 | Bayer Ag | Neue 4-(2-Oxodihydrooxadiazinylphenyl)amide und ihre Verwendung |
| SG93209A1 (en) | 1999-07-05 | 2002-12-17 | Inst Of Molecular Agrobiology | A novel immuno-diagnostic test method for veterinary disease |
| AU6093300A (en) * | 1999-07-14 | 2001-02-05 | Genometrix Genomics Incorporated | Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them |
| KR20000071894A (ko) * | 1999-08-19 | 2000-12-05 | 김선영 | 단백질칩 및 이를 이용한 다목적 자동화 진단시스템 |
| US20030012687A1 (en) | 2000-03-23 | 2003-01-16 | Macphee Martin J. | Methods of sterilizing biological materials |
| AU2002216997A1 (en) * | 2000-11-17 | 2002-06-18 | Zeptosens Ag | Kit and method for multi-analyte determination with arrangements for the positionally resolved referencing of stimulating light intensity |
| US6749851B2 (en) | 2001-08-31 | 2004-06-15 | Clearant, Inc. | Methods for sterilizing preparations of digestive enzymes |
| US7252799B2 (en) | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
| AU2003271637A1 (en) * | 2002-10-09 | 2004-05-04 | Hopitaux Universitaires De Geneve | Analytical chip for detection of 16s-rrna from clinically relevant bacteria and analytical method based thereon |
| EP1571204B1 (de) * | 2004-03-04 | 2009-11-18 | LeukoCare AG | Leukozytenstimulations-Matrix |
-
2006
- 2006-05-05 EP EP06009343A patent/EP1852443A1/en not_active Withdrawn
-
2007
- 2007-05-07 JP JP2009508232A patent/JP5869201B2/ja not_active Expired - Fee Related
- 2007-05-07 WO PCT/EP2007/004016 patent/WO2007128550A1/en not_active Ceased
- 2007-05-07 EP EP07724940A patent/EP2021374B1/en not_active Revoked
- 2007-05-07 US US12/299,382 patent/US9926383B2/en active Active
- 2007-05-07 RU RU2008147885/13A patent/RU2008147885A/ru unknown
- 2007-05-07 BR BRPI0710920-2A patent/BRPI0710920A2/pt not_active IP Right Cessation
- 2007-05-07 CN CN2007800163280A patent/CN101437853B/zh not_active Expired - Fee Related
- 2007-05-07 AT AT07724940T patent/ATE525402T1/de not_active IP Right Cessation
-
2014
- 2014-03-05 JP JP2014043050A patent/JP2014139575A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE525402T1 (de) | 2011-10-15 |
| US9926383B2 (en) | 2018-03-27 |
| JP2014139575A (ja) | 2014-07-31 |
| US20090269778A1 (en) | 2009-10-29 |
| CN101437853A (zh) | 2009-05-20 |
| WO2007128550A1 (en) | 2007-11-15 |
| EP2021374B1 (en) | 2011-09-21 |
| JP2009536025A (ja) | 2009-10-08 |
| EP2021374A1 (en) | 2009-02-11 |
| JP5869201B2 (ja) | 2016-02-24 |
| BRPI0710920A2 (pt) | 2012-03-06 |
| EP1852443A1 (en) | 2007-11-07 |
| CN101437853B (zh) | 2012-07-04 |
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