RU2006102033A - Таблетки, содержащие энрофлоксацин и вкусовые и/или ароматические вещества - Google Patents
Таблетки, содержащие энрофлоксацин и вкусовые и/или ароматические вещества Download PDFInfo
- Publication number
- RU2006102033A RU2006102033A RU2006102033/15A RU2006102033A RU2006102033A RU 2006102033 A RU2006102033 A RU 2006102033A RU 2006102033/15 A RU2006102033/15 A RU 2006102033/15A RU 2006102033 A RU2006102033 A RU 2006102033A RU 2006102033 A RU2006102033 A RU 2006102033A
- Authority
- RU
- Russia
- Prior art keywords
- tablets containing
- taste
- enrofloxacin
- aromatic substances
- necessary
- Prior art date
Links
- SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 title claims 3
- 229960000740 enrofloxacin Drugs 0.000 title claims 3
- 239000000126 substance Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000019634 flavors Nutrition 0.000 claims 2
- 239000008101 lactose Substances 0.000 claims 2
- 235000013372 meat Nutrition 0.000 claims 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 2
- 239000008108 microcrystalline cellulose Substances 0.000 claims 2
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Claims (2)
1. Таблетки, содержащие от 20 до 45 мас.% энрофлоксацина, от 18 до 35 мас.% лактозы, от 5 до 10 мас.% микрокристаллической целлюлозы и от 5 до 20 мас.% придающих мясной запах ароматизаторов.
2. Способ изготовления таблеток по п.1, в соответствии с которым
(a) смешивают энрофлоксацин, лактозу, при необходимости придающий мясной запах ароматизатор, а также при необходимости дополнительные вспомогательные вещества,
(b) гранулируют смесь при добавлении воды или водных растворов дополнительных вспомогательных веществ,
(c) полученную смесь подвергают сушке,
(d) после сушки добавляют микрокристаллическую целлюлозу и при необходимости дополнительные вспомогательные вещества, а также придающий мясной запах ароматизатор, если он не был добавлен на стадии (а),
(e) в заключение из смеси формуют таблетки.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10328666.7 | 2003-06-26 | ||
| DE10328666A DE10328666A1 (de) | 2003-06-26 | 2003-06-26 | Tabletten enthaltend Geschmacks-und/oder Aromastoffe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006102033A true RU2006102033A (ru) | 2006-06-10 |
| RU2359699C2 RU2359699C2 (ru) | 2009-06-27 |
Family
ID=33520986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006102033/15A RU2359699C2 (ru) | 2003-06-26 | 2004-06-14 | Таблетки, содержащие энрофлоксацин и вкусовые и/или ароматические вещества |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20090028936A1 (ru) |
| EP (1) | EP1641439B1 (ru) |
| JP (2) | JP5427341B2 (ru) |
| KR (1) | KR101119917B1 (ru) |
| CN (1) | CN100548280C (ru) |
| AR (2) | AR044704A1 (ru) |
| AU (1) | AU2004251003B2 (ru) |
| BR (1) | BRPI0411771B1 (ru) |
| CA (1) | CA2530639C (ru) |
| CO (1) | CO5650223A2 (ru) |
| CR (1) | CR8149A (ru) |
| DE (2) | DE10328666A1 (ru) |
| DK (1) | DK1641439T3 (ru) |
| ES (1) | ES2280973T3 (ru) |
| GT (1) | GT200400124A (ru) |
| HK (1) | HK1095515A1 (ru) |
| IL (1) | IL172739A (ru) |
| MX (1) | MXPA05013875A (ru) |
| MY (1) | MY135825A (ru) |
| NO (1) | NO338438B1 (ru) |
| NZ (1) | NZ544365A (ru) |
| PE (1) | PE20050502A1 (ru) |
| PL (1) | PL1641439T3 (ru) |
| PT (1) | PT1641439E (ru) |
| RU (1) | RU2359699C2 (ru) |
| SI (1) | SI1641439T1 (ru) |
| TW (1) | TWI339124B (ru) |
| UA (1) | UA82529C2 (ru) |
| UY (1) | UY28380A1 (ru) |
| WO (1) | WO2005000275A1 (ru) |
| ZA (1) | ZA200510318B (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100341510C (zh) * | 2005-06-10 | 2007-10-10 | 冯莉萍 | 一种恩诺沙星微囊及制备方法 |
| CN100360131C (zh) * | 2006-01-24 | 2008-01-09 | 新昌国邦化学工业有限公司 | 一种掩味恩诺沙星的生产方法 |
| WO2010034853A1 (es) | 2008-09-23 | 2010-04-01 | Laboratorio Jaer, S.A. | Utilización de exilitol o sus derivados para el enmascaramiento gustativo de quimioterapicos del grupo del ácido quinolon-o-naftiridoncarboxilico administrados en alimentos destinados a ganado porcino |
| MX347401B (es) * | 2012-11-14 | 2017-04-18 | Univ Mexico Nac Autonoma | Composicion de vehiculos y formas farmaceuticas de liberacion sostenida y aumento de biodisponibilidad de antibacterianos, anticoccidianos y otros farmacos en aves comericales y cerdos. |
| KR102253847B1 (ko) | 2012-12-19 | 2021-05-21 | 바이엘 애니멀 헬스 게엠베하 | 향상된 수용성 및 우수한 저장 안정성을 가지는 정제 |
| RU2554748C2 (ru) * | 2013-07-09 | 2015-06-27 | Общество с ограниченной ответственностью "БИОН" | Средство для лечения энтеритов у животных |
| MX356443B (es) * | 2013-12-11 | 2018-05-21 | Univ Mexico Nac Autonoma | Complejo recristalizado de clorhidrato de enrofloxacina dihidratado, y metodo para obtener el mismo. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3719764A1 (de) * | 1987-06-13 | 1988-12-22 | Bayer Ag | Ionenaustauscherharze beladen mit chinoloncarbonsaeurederivaten, ihre herstellung und verwendung |
| EP0651640A1 (en) * | 1992-07-21 | 1995-05-10 | Knoll AG | Use of 7-fluoro-1-methyl-3-methylsulphinyl-4-quinolone in the treatment of angina pectoris |
| DE19633480A1 (de) * | 1996-08-20 | 1998-02-26 | Bayer Ag | Oral applizierbare Formulierungen von Chinolon- und Naphthyridoncarbonsäuren |
| JP3950175B2 (ja) * | 1997-05-30 | 2007-07-25 | オスモティカ・コーポレイション | 多層浸透デバイス |
| US5980914A (en) * | 1997-08-22 | 1999-11-09 | P.N. Gerolymatos S.A. | Clioquinol for the treatment of Parkinson's disease |
| DE10031044A1 (de) * | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
| EP1247456A3 (en) * | 2001-02-28 | 2003-12-10 | Pfizer Products Inc. | Palatable pharmaceutical compositions for companion animals |
| US20030190343A1 (en) * | 2002-03-05 | 2003-10-09 | Pfizer Inc. | Palatable pharmaceutical compositions for companion animals |
-
2003
- 2003-06-26 DE DE10328666A patent/DE10328666A1/de not_active Withdrawn
-
2004
- 2004-06-14 EP EP04739854A patent/EP1641439B1/de active Active
- 2004-06-14 PT PT04739854T patent/PT1641439E/pt unknown
- 2004-06-14 MX MXPA05013875A patent/MXPA05013875A/es active IP Right Grant
- 2004-06-14 CN CNB2004800180704A patent/CN100548280C/zh active Active
- 2004-06-14 ES ES04739854T patent/ES2280973T3/es active Active
- 2004-06-14 PL PL04739854T patent/PL1641439T3/pl unknown
- 2004-06-14 BR BRPI0411771A patent/BRPI0411771B1/pt active IP Right Grant
- 2004-06-14 KR KR1020057024584A patent/KR101119917B1/ko active IP Right Grant
- 2004-06-14 CA CA2530639A patent/CA2530639C/en active Active
- 2004-06-14 US US10/559,995 patent/US20090028936A1/en not_active Abandoned
- 2004-06-14 DK DK04739854T patent/DK1641439T3/da active
- 2004-06-14 JP JP2006515918A patent/JP5427341B2/ja active Active
- 2004-06-14 DE DE502004002690T patent/DE502004002690D1/de active Active
- 2004-06-14 WO PCT/EP2004/006370 patent/WO2005000275A1/de active Application Filing
- 2004-06-14 RU RU2006102033/15A patent/RU2359699C2/ru active
- 2004-06-14 AU AU2004251003A patent/AU2004251003B2/en active Active
- 2004-06-14 UA UAA200600683A patent/UA82529C2/ru unknown
- 2004-06-14 SI SI200430201T patent/SI1641439T1/sl unknown
- 2004-06-14 NZ NZ544365A patent/NZ544365A/en unknown
- 2004-06-15 AR ARP040102069A patent/AR044704A1/es not_active Application Discontinuation
- 2004-06-22 GT GT200400124A patent/GT200400124A/es unknown
- 2004-06-23 UY UY28380A patent/UY28380A1/es active IP Right Grant
- 2004-06-24 MY MYPI20042477A patent/MY135825A/en unknown
- 2004-06-25 TW TW093118390A patent/TWI339124B/zh active
- 2004-06-25 PE PE2004000619A patent/PE20050502A1/es active IP Right Grant
-
2005
- 2005-12-14 CR CR8149A patent/CR8149A/es not_active Application Discontinuation
- 2005-12-20 ZA ZA200510318A patent/ZA200510318B/en unknown
- 2005-12-21 IL IL172739A patent/IL172739A/en active IP Right Grant
- 2005-12-26 CO CO05129984A patent/CO5650223A2/es not_active Application Discontinuation
-
2006
- 2006-01-05 NO NO20060065A patent/NO338438B1/no unknown
-
2007
- 2007-01-17 HK HK07100602.3A patent/HK1095515A1/xx unknown
-
2011
- 2011-10-06 JP JP2011221646A patent/JP2012046533A/ja active Pending
-
2016
- 2016-01-29 AR ARP160100259A patent/AR103567A2/es not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HK4A | Changes in a published invention | ||
| PC4A | Invention patent assignment |
Effective date: 20100201 |
|
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20130207 |