RU2005105683A - Обладающие ингибирующим действием на vegfr-2 и vegfr-3 антраниламидопиридины - Google Patents

Обладающие ингибирующим действием на vegfr-2 и vegfr-3 антраниламидопиридины Download PDF

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RU2005105683A
RU2005105683A RU2005105683/04A RU2005105683A RU2005105683A RU 2005105683 A RU2005105683 A RU 2005105683A RU 2005105683/04 A RU2005105683/04 A RU 2005105683/04A RU 2005105683 A RU2005105683 A RU 2005105683A RU 2005105683 A RU2005105683 A RU 2005105683A
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RU2005105683/04A
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Андреас ХУТ (DE)
Андреас Хут
Мартин КРЮГЕР (DE)
Мартин Крюгер
Людвиг ЦОРН (DE)
Людвиг Цорн
Стуарт ИНЦЕ (DE)
Стуарт ИНЦЕ
Карл-Хайнц ТИРАУХ (DE)
Карл-Хайнц Тираух
Андреас МЕНРАД (DE)
Андреас Менрад
Мартин ХАБЕРЕЙ (DE)
Мартин Хаберей
Хольгер ХЕСС-ШТУМП (DE)
Хольгер Хесс-Штумп
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Шеринг Акциенгезельшафт (De)
Шеринг Акциенгезельшафт
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Priority claimed from DE10235690A external-priority patent/DE10235690A1/de
Priority claimed from DE10328036A external-priority patent/DE10328036A1/de
Application filed by Шеринг Акциенгезельшафт (De), Шеринг Акциенгезельшафт filed Critical Шеринг Акциенгезельшафт (De)
Publication of RU2005105683A publication Critical patent/RU2005105683A/ru

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
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  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
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RU2005105683/04A 2002-07-31 2003-07-22 Обладающие ингибирующим действием на vegfr-2 и vegfr-3 антраниламидопиридины RU2005105683A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10235690A DE10235690A1 (de) 2002-07-31 2002-07-31 VEGFR-2 und VEGFR-3 inhibitorische Anthranylamidpyridinamide
DE10235690.4 2002-07-31
DE10328036.7 2003-06-19
DE10328036A DE10328036A1 (de) 2003-06-19 2003-06-19 VEGFR-2 und VEGFR-3 inhibitorische Anthranylamidpyridine

Publications (1)

Publication Number Publication Date
RU2005105683A true RU2005105683A (ru) 2006-01-20

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RU2005105683/04A RU2005105683A (ru) 2002-07-31 2003-07-22 Обладающие ингибирующим действием на vegfr-2 и vegfr-3 антраниламидопиридины

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EP (1) EP1594841A1 (de)
JP (2) JP4777648B2 (de)
KR (1) KR20050026535A (de)
CN (1) CN1671666A (de)
AU (1) AU2003281855A1 (de)
BR (1) BR0313122A (de)
CA (1) CA2493026C (de)
CO (1) CO5720998A2 (de)
CR (1) CR7673A (de)
EC (1) ECSP055631A (de)
HR (1) HRP20050187A2 (de)
IL (1) IL166377A0 (de)
MX (1) MXPA04012948A (de)
NO (1) NO20051035L (de)
PL (1) PL374610A1 (de)
RS (1) RS20050084A (de)
RU (1) RU2005105683A (de)
WO (1) WO2004013102A1 (de)

Families Citing this family (37)

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US7615565B2 (en) 2002-07-31 2009-11-10 Bayer Schering Pharma Aktiengesellschaft VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridines
GB0229022D0 (en) * 2002-12-12 2003-01-15 Novartis Ag Organic Compounds
WO2004064730A2 (en) 2003-01-14 2004-08-05 Cytokinetics, Inc. Compounds, compositions and methods
DE102004009238A1 (de) * 2004-02-26 2005-09-08 Merck Patent Gmbh Arylamid-Derivate
TWI359812B (en) 2004-06-17 2012-03-11 Cytokinetics Inc Compounds, compositions and methods
US7176222B2 (en) 2004-07-27 2007-02-13 Cytokinetics, Inc. Syntheses of ureas
EP1657241A1 (de) * 2004-11-03 2006-05-17 Schering Aktiengesellschaft Neue Antranilamidpyrdinharnstoffe mit hemmender Wirkung auf VEGF-Rezeptor Kinase
EP1655295A1 (de) * 2004-11-03 2006-05-10 Schering Aktiengesellschaft Anthranilamid-Pyridinharnstoffe als VEGF Rezeptor Kinase Inhibitoren
US7906533B2 (en) 2004-11-03 2011-03-15 Bayer Schering Pharma Ag Nicotinamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors
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AU2003281855A1 (en) 2004-02-23
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