RU2001127313A - Конъюгаты жирная кислота-противораковый агент и их применение - Google Patents

Конъюгаты жирная кислота-противораковый агент и их применение Download PDF

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Publication number
RU2001127313A
RU2001127313A RU2001127313/14A RU2001127313A RU2001127313A RU 2001127313 A RU2001127313 A RU 2001127313A RU 2001127313/14 A RU2001127313/14 A RU 2001127313/14A RU 2001127313 A RU2001127313 A RU 2001127313A RU 2001127313 A RU2001127313 A RU 2001127313A
Authority
RU
Russia
Prior art keywords
fatty acid
acid
conjugate
taxane
composition
Prior art date
Application number
RU2001127313/14A
Other languages
English (en)
Russian (ru)
Inventor
Найджел Л. ВЕББ (US)
Найджел Л. ВЕББ
Мэттьюз О. БРЭДЛИ (US)
Мэттьюз О. БРЭДЛИ
Форрест ЭНТОНИ (US)
Форрест ЭНТОНИ
Марк ФИШЕР (US)
Марк Фишер
Original Assignee
Протарга, Инк. (Us)
Протарга, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/265,307 external-priority patent/US7235583B1/en
Application filed by Протарга, Инк. (Us), Протарга, Инк. filed Critical Протарга, Инк. (Us)
Publication of RU2001127313A publication Critical patent/RU2001127313A/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2001127313/14A 1999-03-09 2000-03-09 Конъюгаты жирная кислота-противораковый агент и их применение RU2001127313A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/265,307 1999-03-09
US09/265,307 US7235583B1 (en) 1999-03-09 1999-03-09 Fatty acid-anticancer conjugates and uses thereof
US18615200P 2000-03-01 2000-03-01
US60/186,152 2000-03-01

Publications (1)

Publication Number Publication Date
RU2001127313A true RU2001127313A (ru) 2003-09-20

Family

ID=26881822

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2001127313/14A RU2001127313A (ru) 1999-03-09 2000-03-09 Конъюгаты жирная кислота-противораковый агент и их применение

Country Status (10)

Country Link
EP (1) EP1163011A2 (cs)
JP (1) JP2002538224A (cs)
KR (1) KR20020000147A (cs)
CN (1) CN1377282A (cs)
AU (1) AU3733300A (cs)
CA (1) CA2366723C (cs)
CZ (1) CZ20013123A3 (cs)
HK (1) HK1040486A1 (cs)
RU (1) RU2001127313A (cs)
WO (1) WO2000053231A2 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994392A (en) * 1988-02-26 1999-11-30 Neuromedica, Inc. Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid
JP2005500988A (ja) * 2001-03-23 2005-01-13 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪族アミン薬物複合体
ATE556706T1 (de) * 2001-03-23 2012-05-15 Luitpold Pharm Inc Fettalkohol-arzneimittel-konjugate
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
EP1509256B1 (en) 2002-05-24 2009-07-22 Angiotech International Ag Compositions and methods for coating medical implants
CA2529125A1 (en) * 2003-06-19 2004-12-23 Yeda Research & Development Co. Ltd. Antimicrobial and anticancer lipopeptides
AU2004285529A1 (en) * 2003-10-30 2005-05-12 The Research Foundation of University of New York York Taxoid-fatty acid conjugates and pharmaceutical compositions thereof
EP1862183B1 (en) * 2005-03-14 2010-11-03 Otsuka Pharmaceutical Factory, Inc. Kit comprising drug and fat emulsion
KR100753112B1 (ko) * 2007-02-26 2007-08-29 (주)고려다이나믹스 카드 발권 시스템
BR112015000236A2 (pt) * 2012-07-10 2017-06-27 Baseclick Gmbh moléculas de ácidos nucleicos modificadas por anandamida
CN117088935A (zh) * 2022-05-20 2023-11-21 上海维洱生物医药科技有限公司 一种雷公藤甲素木蜡酸酯及其脂质体与制备方法
KR20230174082A (ko) * 2022-06-20 2023-12-27 (주) 바이오인프라생명과학 약물을 전달하기 위한 초음파 감응형 약물전달체를 생성하는 방법 및 이를 이용한 초음파 감응형 약물전달체
CN116676355B (zh) * 2023-08-03 2023-10-24 成都第一制药有限公司 一种催化合成山莨菪碱的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法
CA2125279A1 (en) * 1991-12-10 1993-06-24 John Sayler Coon Methods and compositions for reducing multi-drug resistance
US5925669A (en) * 1994-03-22 1999-07-20 Molecular/Structural Bio Technologies, Inc. Carrier compositions for anti-neoplastic drugs
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
CA2255615C (en) * 1996-05-22 2006-08-29 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6136988A (en) * 1998-04-10 2000-10-24 Hauser, Inc. 7-hexanoyltaxol and methods for preparing the same

Also Published As

Publication number Publication date
CA2366723C (en) 2011-08-02
AU3733300A (en) 2000-09-28
JP2002538224A (ja) 2002-11-12
CA2366723A1 (en) 2000-09-14
EP1163011A2 (en) 2001-12-19
KR20020000147A (ko) 2002-01-04
WO2000053231A3 (en) 2001-10-04
WO2000053231A2 (en) 2000-09-14
CN1377282A (zh) 2002-10-30
CZ20013123A3 (cs) 2002-03-13
HK1040486A1 (zh) 2002-06-14

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Effective date: 20050111