RS61715B1 - Inhibicija jonskog kanala tranzitornog receptorskog potencijala a1 - Google Patents

Inhibicija jonskog kanala tranzitornog receptorskog potencijala a1

Info

Publication number
RS61715B1
RS61715B1 RS20210455A RSP20210455A RS61715B1 RS 61715 B1 RS61715 B1 RS 61715B1 RS 20210455 A RS20210455 A RS 20210455A RS P20210455 A RSP20210455 A RS P20210455A RS 61715 B1 RS61715 B1 RS 61715B1
Authority
RS
Serbia
Prior art keywords
inhibiting
ion channel
transient receptor
receptor potential
transient
Prior art date
Application number
RS20210455A
Other languages
English (en)
Serbian (sr)
Inventor
Blaise S Lippa
Qingyi Li
Iwona Wrona
Andrew J Jackson
Christopher M Liu
Guohua Liang
Matthew F Baevsky
Richard Alan Earl
Lisa Mcqueen
Jared Smit
Brett Cowans
Xinyuan Wu
Bertrand L Chenard
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of RS61715B1 publication Critical patent/RS61715B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Discharging, Photosensitive Material Shape In Electrophotography (AREA)
  • Electrotherapy Devices (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
RS20210455A 2014-04-23 2015-04-23 Inhibicija jonskog kanala tranzitornog receptorskog potencijala a1 RS61715B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461983223P 2014-04-23 2014-04-23
US201461987272P 2014-05-01 2014-05-01
EP15722319.9A EP3134410B1 (de) 2014-04-23 2015-04-23 Ionenkanalhemmung des übergangsrezeptorpotentials a1
PCT/US2015/027353 WO2015164643A1 (en) 2014-04-23 2015-04-23 Inhibiting the transient receptor potential a1 ion channel

Publications (1)

Publication Number Publication Date
RS61715B1 true RS61715B1 (sr) 2021-05-31

Family

ID=53175632

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20210455A RS61715B1 (sr) 2014-04-23 2015-04-23 Inhibicija jonskog kanala tranzitornog receptorskog potencijala a1

Country Status (18)

Country Link
US (2) US20170050966A1 (de)
EP (1) EP3134410B1 (de)
JP (1) JP6557680B2 (de)
CN (1) CN106573934B (de)
AU (1) AU2015252007B2 (de)
CA (1) CA2945789C (de)
CY (1) CY1124243T1 (de)
DK (1) DK3134410T3 (de)
ES (1) ES2865173T3 (de)
HR (1) HRP20210613T1 (de)
HU (1) HUE054066T2 (de)
LT (1) LT3134410T (de)
PL (1) PL3134410T3 (de)
PT (1) PT3134410T (de)
RS (1) RS61715B1 (de)
SI (1) SI3134410T1 (de)
TW (1) TWI676626B (de)
WO (1) WO2015164643A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3193880T (pt) 2014-09-19 2020-06-19 Lilly Co Eli Inibição do canal iónico receptor de potencial transitório a1
EP3554500A1 (de) * 2016-12-16 2019-10-23 Galderma Research & Development Trpa1-antagonisten zur behandlung von atopischer dermatitis
WO2019011802A1 (en) * 2017-07-11 2019-01-17 Boehringer Ingelheim International Gmbh NEW SUBSTITUTED XANTHINE DERIVATIVES
EP3746445A1 (de) 2018-01-31 2020-12-09 Eli Lilly And Company Hemmung des ionenkanals des übergangsrezeptorpotenzials a1
BR112021007692A2 (pt) * 2018-10-23 2021-08-10 George Edward Hoag composição e método para tratar os pulmões
FR3114235A1 (fr) 2020-09-18 2022-03-25 Université Grenoble Alpes Inhibition du canal trpa1 astrocytaire comme nouvelle cible therapeutique neuroprotectrice dans les phases prodromales de la maladie d’alzheimer
IT202100015098A1 (it) 2021-06-09 2022-12-09 Flonext S R L Composto antagonista del canale trpa1 per uso in patologie degenerative della retina
WO2023133502A1 (en) * 2022-01-07 2023-07-13 The Johns Hopkins University Treatment and prevention of trigeminal neuralgia
CN114671875A (zh) * 2022-04-27 2022-06-28 成都施贝康生物医药科技有限公司 新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途
CN114656473B (zh) * 2022-04-27 2023-09-29 成都施贝康生物医药科技有限公司 吡咯并嘧啶类化合物、异构体或盐及其制备方法和用途
CN114656472B (zh) * 2022-04-27 2023-07-04 成都施贝康生物医药科技有限公司 吡唑并嘧啶类化合物、异构体或盐及其制备方法和用途
CN114656480B (zh) * 2022-04-27 2024-01-26 成都施贝康生物医药科技有限公司 噻吩并嘧啶类化合物、异构体或盐及其制备方法和用途
CN114671876B (zh) * 2022-04-27 2023-10-03 成都施贝康生物医药科技有限公司 新型茶碱类化合物、异构体或盐及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI610684B (zh) 2005-12-22 2018-01-11 海卓勒生物科學公司 用於調節ｔｒｐａ１功能之化合物
WO2009002933A1 (en) * 2007-06-22 2008-12-31 Hydra Biosciences, Inc. Methods and compositions for treating disorders
WO2009140517A1 (en) * 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2010036821A1 (en) * 2008-09-24 2010-04-01 Hydra Biosciences, Inc. Methods and compositions for treating respiratory disorders
RU2014108885A (ru) * 2011-08-09 2015-09-20 Хайдра Байосайенсиз, Инк. Ингибирование транзиторного рецепторного потенциала ионного канала trpa1
TW201441225A (zh) * 2013-01-18 2014-11-01 Cubist Pharm Inc 瞬時受體電位ａ１離子通道之抑制
GB201309333D0 (en) * 2013-05-23 2013-07-10 Agency Science Tech & Res Purine diones as WNT pathway modulators
PT3193880T (pt) * 2014-09-19 2020-06-19 Lilly Co Eli Inibição do canal iónico receptor de potencial transitório a1
EP3256463B1 (de) * 2015-02-15 2019-10-09 F. Hoffmann-La Roche AG 1-(het)arylsulfonyl-(pyrrolidin oder piperidin)-2-carboxamid- derivate und ihre verwendung als trpa1 antagonisten

Also Published As

Publication number Publication date
JP6557680B2 (ja) 2019-08-07
HRP20210613T1 (hr) 2021-05-28
CN106573934B (zh) 2019-10-11
ES2865173T3 (es) 2021-10-15
TWI676626B (zh) 2019-11-11
CN106573934A (zh) 2017-04-19
JP2017516763A (ja) 2017-06-22
PL3134410T3 (pl) 2021-07-12
AU2015252007B2 (en) 2019-08-22
EP3134410B1 (de) 2021-03-10
HUE054066T2 (hu) 2021-08-30
US10428072B2 (en) 2019-10-01
DK3134410T3 (da) 2021-04-26
SI3134410T1 (sl) 2021-04-30
CY1124243T1 (el) 2022-07-22
US20170050966A1 (en) 2017-02-23
WO2015164643A1 (en) 2015-10-29
US20180230149A1 (en) 2018-08-16
TW201625618A (zh) 2016-07-16
CA2945789A1 (en) 2015-10-29
LT3134410T (lt) 2021-04-26
PT3134410T (pt) 2021-04-22
EP3134410A1 (de) 2017-03-01
CA2945789C (en) 2022-08-30
AU2015252007A1 (en) 2016-10-13

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