RS55313B1 - Ariletinil derivati - Google Patents

Ariletinil derivati

Info

Publication number
RS55313B1
RS55313B1 RS20160979A RSP20160979A RS55313B1 RS 55313 B1 RS55313 B1 RS 55313B1 RS 20160979 A RS20160979 A RS 20160979A RS P20160979 A RSP20160979 A RS P20160979A RS 55313 B1 RS55313 B1 RS 55313B1
Authority
RS
Serbia
Prior art keywords
arylethynyl
derivatives
arylethynyl derivatives
Prior art date
Application number
RS20160979A
Other languages
English (en)
Inventor
Georg Jaeschke
Lothar Lindemann
Heinz Stadler
Eric Vieira
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of RS55313B1 publication Critical patent/RS55313B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RS20160979A 2012-07-17 2013-07-12 Ariletinil derivati RS55313B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12176662 2012-07-17
PCT/EP2013/064747 WO2014012851A1 (en) 2012-07-17 2013-07-12 Arylethynyl derivatives
EP13735315.7A EP2875000B1 (en) 2012-07-17 2013-07-12 Arylethynyl derivatives

Publications (1)

Publication Number Publication Date
RS55313B1 true RS55313B1 (sr) 2017-03-31

Family

ID=48782352

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20160979A RS55313B1 (sr) 2012-07-17 2013-07-12 Ariletinil derivati

Country Status (36)

Country Link
US (2) US20150133505A1 (sr)
EP (1) EP2875000B1 (sr)
JP (1) JP6089104B2 (sr)
KR (1) KR101631041B1 (sr)
CN (1) CN104364233B (sr)
AR (1) AR091764A1 (sr)
AU (1) AU2013292142B2 (sr)
BR (1) BR112014029015A2 (sr)
CA (1) CA2871389C (sr)
CL (1) CL2014003160A1 (sr)
CO (1) CO7111256A2 (sr)
CR (1) CR20140531A (sr)
CY (1) CY1118205T1 (sr)
DK (1) DK2875000T3 (sr)
EA (1) EA026593B1 (sr)
ES (1) ES2600133T3 (sr)
HK (1) HK1202544A1 (sr)
HR (1) HRP20161691T1 (sr)
HU (1) HUE030177T2 (sr)
IL (1) IL236362A (sr)
LT (1) LT2875000T (sr)
MA (1) MA20150280A2 (sr)
MX (1) MX358998B (sr)
MY (1) MY167810A (sr)
NZ (1) NZ701849A (sr)
PE (1) PE20150184A1 (sr)
PH (1) PH12014502695B1 (sr)
PL (1) PL2875000T3 (sr)
PT (1) PT2875000T (sr)
RS (1) RS55313B1 (sr)
SG (1) SG11201407050UA (sr)
SI (1) SI2875000T1 (sr)
TW (1) TWI473799B (sr)
UA (1) UA114911C2 (sr)
WO (1) WO2014012851A1 (sr)
ZA (1) ZA201408514B (sr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA113223C2 (xx) * 2012-08-13 2016-12-26 Арилетинілпіримідини
MY171517A (en) * 2012-10-18 2019-10-16 Hoffmann La Roche Ethynyl derivatives as modulators of mglur5 receptor activity
PL3303316T3 (pl) 2015-06-03 2020-06-29 F. Hoffmann-La Roche Ag Pochodne etynylu

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546462A1 (de) * 1995-12-13 1997-06-19 Bayer Ag Diarylacetylenketone
DK1354875T3 (da) 2003-05-19 2005-03-14 Servier Lab Ny syntesefremgangsmåde for (2S, 3aS, 7aS)-perhydroindol-2-carboxylsyre og estere heraf samt anvendelse ved syntese af perindopril
GB0325956D0 (en) 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
EP1809620B1 (en) 2004-11-04 2010-12-29 Addex Pharma SA Novel tetrazole derivatives as positive allosteric modulators of metabotropic glutamate receptors
GB0510139D0 (en) 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B1
WO2008151184A1 (en) 2007-06-03 2008-12-11 Vanderbilt University Benzamide mglur5 positive allosteric modulators and methods of making and using same
CN101544892B (zh) * 2009-05-07 2012-10-03 石家庄诚志永华显示材料有限公司 一种合成二芳基乙炔类单体液晶的方法
US8420661B2 (en) * 2010-04-13 2013-04-16 Hoffmann-La Roche Inc. Arylethynyl derivatives
MY163164A (en) * 2011-04-26 2017-08-15 Hoffmann La Roche Ethynyl derivatives as positive allosteric modulators of the mglur5

Also Published As

Publication number Publication date
TWI473799B (zh) 2015-02-21
AU2013292142B2 (en) 2017-03-09
MA20150280A2 (fr) 2015-08-31
MY167810A (en) 2018-09-26
US20160039787A1 (en) 2016-02-11
CN104364233A (zh) 2015-02-18
JP2015527993A (ja) 2015-09-24
DK2875000T3 (en) 2016-10-24
PE20150184A1 (es) 2015-02-13
CN104364233B (zh) 2016-06-22
CA2871389C (en) 2020-08-25
BR112014029015A2 (pt) 2017-06-27
PT2875000T (pt) 2016-11-03
HUE030177T2 (en) 2017-04-28
MX358998B (es) 2018-09-12
WO2014012851A1 (en) 2014-01-23
NZ701849A (en) 2016-07-29
IL236362A0 (en) 2015-02-26
HRP20161691T1 (hr) 2017-02-24
IL236362A (en) 2017-12-31
AR091764A1 (es) 2015-02-25
JP6089104B2 (ja) 2017-03-01
KR101631041B1 (ko) 2016-06-15
ZA201408514B (en) 2015-12-23
SI2875000T1 (sl) 2017-01-31
EA026593B1 (ru) 2017-04-28
MX2014014950A (es) 2015-03-09
CR20140531A (es) 2015-01-12
SG11201407050UA (en) 2014-11-27
CL2014003160A1 (es) 2015-03-13
PH12014502695A1 (en) 2015-01-26
EP2875000A1 (en) 2015-05-27
AU2013292142A1 (en) 2014-11-06
EA201492274A1 (ru) 2015-05-29
CA2871389A1 (en) 2014-01-23
LT2875000T (lt) 2016-11-10
PL2875000T3 (pl) 2017-03-31
TW201408655A (zh) 2014-03-01
US9328090B2 (en) 2016-05-03
EP2875000B1 (en) 2016-09-21
CO7111256A2 (es) 2014-11-10
US20150133505A1 (en) 2015-05-14
HK1202544A1 (zh) 2015-10-02
CY1118205T1 (el) 2017-06-28
UA114911C2 (uk) 2017-08-28
PH12014502695B1 (en) 2015-01-26
ES2600133T3 (es) 2017-02-07
KR20150023766A (ko) 2015-03-05

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