RS53745B1 - 6-amino-2-{[(1s)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8h-purin-8-on-maleat - Google Patents
6-amino-2-{[(1s)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8h-purin-8-on-maleatInfo
- Publication number
- RS53745B1 RS53745B1 RS20150005A RSP20150005A RS53745B1 RS 53745 B1 RS53745 B1 RS 53745B1 RS 20150005 A RS20150005 A RS 20150005A RS P20150005 A RSP20150005 A RS P20150005A RS 53745 B1 RS53745 B1 RS 53745B1
- Authority
- RS
- Serbia
- Prior art keywords
- purin
- amino
- dihydro
- methylbutyl
- piperidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30301010P | 2010-02-10 | 2010-02-10 | |
| PCT/EP2011/051830 WO2011098452A1 (en) | 2010-02-10 | 2011-02-08 | 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS53745B1 true RS53745B1 (sr) | 2015-06-30 |
Family
ID=43836817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20150005A RS53745B1 (sr) | 2010-02-10 | 2011-02-08 | 6-amino-2-{[(1s)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8h-purin-8-on-maleat |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8703754B2 (OSRAM) |
| EP (1) | EP2534149B1 (OSRAM) |
| JP (1) | JP5922587B2 (OSRAM) |
| KR (1) | KR101773541B1 (OSRAM) |
| CN (1) | CN102753553B (OSRAM) |
| AU (1) | AU2011214468B2 (OSRAM) |
| BR (1) | BR112012018904A2 (OSRAM) |
| CA (1) | CA2786973C (OSRAM) |
| DK (1) | DK2534149T3 (OSRAM) |
| EA (1) | EA021048B1 (OSRAM) |
| ES (1) | ES2525826T3 (OSRAM) |
| HR (1) | HRP20141258T1 (OSRAM) |
| IL (1) | IL220845A (OSRAM) |
| ME (1) | ME01926B (OSRAM) |
| MX (1) | MX2012009316A (OSRAM) |
| PL (1) | PL2534149T3 (OSRAM) |
| PT (1) | PT2534149E (OSRAM) |
| RS (1) | RS53745B1 (OSRAM) |
| SG (1) | SG182471A1 (OSRAM) |
| SI (1) | SI2534149T1 (OSRAM) |
| SM (1) | SMT201400196B (OSRAM) |
| WO (1) | WO2011098452A1 (OSRAM) |
| ZA (1) | ZA201205995B (OSRAM) |
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| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| SG171914A1 (en) | 2008-12-02 | 2011-07-28 | Chiralgen Ltd | Method for the synthesis of phosphorus atom modified nucleic acids |
| IN2012DN00720A (OSRAM) | 2009-07-06 | 2015-06-19 | Ontorii Inc | |
| EA020488B1 (ru) | 2009-10-22 | 2014-11-28 | Джилид Сайэнс, Инк. | Производные пурина или деазапурина для применения при лечении вирусных инфекций и других заболеваний |
| WO2012039448A1 (ja) | 2010-09-24 | 2012-03-29 | 株式会社キラルジェン | 不斉補助基 |
| MX347361B (es) | 2011-07-19 | 2017-04-12 | Wave Life Sciences Ltd | Metodos para la sintesis de acidos nucleicos funcionalizados. |
| WO2013014052A1 (en) * | 2011-07-22 | 2013-01-31 | Glaxosmithkline Llc | Composition |
| EP2872147B1 (en) | 2012-07-13 | 2022-12-21 | Wave Life Sciences Ltd. | Method for making chiral oligonucleotides |
| EP2872485B1 (en) | 2012-07-13 | 2020-12-16 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| AU2013287630B2 (en) * | 2012-07-13 | 2017-05-25 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant |
| BR112015003259A2 (pt) | 2012-08-24 | 2017-08-08 | Glaxosmithkline Llc | composto, composição farmacêutica, e, composição de vacina. |
| WO2014081643A1 (en) | 2012-11-20 | 2014-05-30 | Glaxosmithkline Llc | Novel compounds |
| PT2922549T (pt) | 2012-11-20 | 2017-09-01 | Glaxosmithkline Llc | Novos compostos |
| WO2014081644A1 (en) | 2012-11-20 | 2014-05-30 | Glaxosmithkline Llc | Novel compounds |
| EP3095460A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| US10144933B2 (en) | 2014-01-15 | 2018-12-04 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
| JPWO2015108048A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| CN106068325B (zh) | 2014-01-16 | 2021-07-09 | 波涛生命科学有限公司 | 手性设计 |
| JP7109188B2 (ja) * | 2014-08-29 | 2022-07-29 | コリウム， インコーポレイテッド | 活性剤の送達のための微細構造アレイ |
| CA2967248A1 (en) * | 2014-11-13 | 2016-05-19 | Glaxosmithkline Biologicals Sa | Adenine derivatives which are useful in the treatment of allergic diseases or other inflammatory conditions |
| WO2020110584A1 (ja) * | 2018-11-28 | 2020-06-04 | 株式会社島津製作所 | アゾ化合物の分析方法 |
| KR20250106231A (ko) | 2023-12-29 | 2025-07-09 | (주)셀트리온 | 안정한 약제학적 제제 |
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| JPWO2007034881A1 (ja) * | 2005-09-22 | 2009-03-26 | 大日本住友製薬株式会社 | 新規アデニン化合物 |
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| US20100120799A1 (en) | 2007-02-19 | 2010-05-13 | Smithkline Beecham Corporation | Purine derivatives as immunomodulators |
| EP2132209B8 (en) * | 2007-03-19 | 2014-04-16 | AstraZeneca AB | 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators |
| UY31531A1 (es) * | 2007-12-17 | 2009-08-03 | Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr) | |
| US8777708B2 (en) | 2008-06-27 | 2014-07-15 | Microsoft Corporation | Targeting control in a simulated environment |
| UA103195C2 (uk) * | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
-
2011
- 2011-02-08 CA CA2786973A patent/CA2786973C/en not_active Expired - Fee Related
- 2011-02-08 MX MX2012009316A patent/MX2012009316A/es active IP Right Grant
- 2011-02-08 WO PCT/EP2011/051830 patent/WO2011098452A1/en not_active Ceased
- 2011-02-08 AU AU2011214468A patent/AU2011214468B2/en not_active Ceased
- 2011-02-08 ES ES11709025.8T patent/ES2525826T3/es active Active
- 2011-02-08 CN CN201180009082.0A patent/CN102753553B/zh not_active Expired - Fee Related
- 2011-02-08 HR HRP20141258AT patent/HRP20141258T1/hr unknown
- 2011-02-08 ME MEP-2014-154A patent/ME01926B/me unknown
- 2011-02-08 BR BR112012018904-2A patent/BR112012018904A2/pt not_active IP Right Cessation
- 2011-02-08 US US13/578,020 patent/US8703754B2/en not_active Expired - Fee Related
- 2011-02-08 EP EP11709025.8A patent/EP2534149B1/en active Active
- 2011-02-08 KR KR1020127023687A patent/KR101773541B1/ko not_active Expired - Fee Related
- 2011-02-08 DK DK11709025.8T patent/DK2534149T3/da active
- 2011-02-08 JP JP2012552369A patent/JP5922587B2/ja active Active
- 2011-02-08 PL PL11709025T patent/PL2534149T3/pl unknown
- 2011-02-08 SG SG2012051140A patent/SG182471A1/en unknown
- 2011-02-08 SI SI201130364T patent/SI2534149T1/sl unknown
- 2011-02-08 PT PT117090258T patent/PT2534149E/pt unknown
- 2011-02-08 EA EA201290631A patent/EA021048B1/ru not_active IP Right Cessation
- 2011-02-08 RS RS20150005A patent/RS53745B1/sr unknown
-
2012
- 2012-07-10 IL IL220845A patent/IL220845A/en not_active IP Right Cessation
- 2012-08-08 ZA ZA2012/05995A patent/ZA201205995B/en unknown
-
2014
- 2014-12-30 SM SM201400196T patent/SMT201400196B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5922587B2 (ja) | 2016-05-24 |
| US8703754B2 (en) | 2014-04-22 |
| CA2786973A1 (en) | 2011-08-18 |
| CN102753553B (zh) | 2016-03-30 |
| CA2786973C (en) | 2018-04-10 |
| AU2011214468B2 (en) | 2015-05-28 |
| MX2012009316A (es) | 2012-09-12 |
| EP2534149A1 (en) | 2012-12-19 |
| ZA201205995B (en) | 2014-01-29 |
| JP2013519645A (ja) | 2013-05-30 |
| WO2011098452A1 (en) | 2011-08-18 |
| EP2534149B1 (en) | 2014-10-15 |
| CN102753553A (zh) | 2012-10-24 |
| AU2011214468A1 (en) | 2012-08-09 |
| US20120308609A1 (en) | 2012-12-06 |
| KR101773541B1 (ko) | 2017-08-31 |
| EA021048B1 (ru) | 2015-03-31 |
| PL2534149T3 (pl) | 2015-03-31 |
| DK2534149T3 (da) | 2015-01-05 |
| SMT201400196B (it) | 2015-01-15 |
| PT2534149E (pt) | 2014-12-23 |
| HRP20141258T1 (hr) | 2015-02-27 |
| SG182471A1 (en) | 2012-08-30 |
| ES2525826T3 (es) | 2014-12-30 |
| EA201290631A1 (ru) | 2013-03-29 |
| KR20120135408A (ko) | 2012-12-13 |
| BR112012018904A2 (pt) | 2020-09-01 |
| IL220845A (en) | 2016-08-31 |
| ME01926B (me) | 2015-05-20 |
| SI2534149T1 (sl) | 2015-02-27 |
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