RS51176B - Aminopurini supstituisani haloarilom, njihove smeše i postupci lečenja pomoću njih - Google Patents

Aminopurini supstituisani haloarilom, njihove smeše i postupci lečenja pomoću njih

Info

Publication number
RS51176B
RS51176B RSP-2009/0402A RSP20090402A RS51176B RS 51176 B RS51176 B RS 51176B RS P20090402 A RSP20090402 A RS P20090402A RS 51176 B RS51176 B RS 51176B
Authority
RS
Serbia
Prior art keywords
compositions
methods
condition
disease
treatment therewith
Prior art date
Application number
RSP-2009/0402A
Other languages
English (en)
Inventor
Ronald Albers
Leticia Ayala
Steven S. Clareen
Maria M. Delgado Mederos
Robert Hilgraf
Sayee Hedge
Kevin Hughes
Adam Kois
Veronique Plantevin-Krenitsky
Meg Mccarrick
Lisa Nadolny
Moorthy Palanki
Kiran Sahasrabudhe
John Sapienza
Yoshitaka Satoh
Marian Sloss
Elise Sudbeck
Jonathan Wright
Andrew G. Cole
Ian Henderson
Original Assignee
Signal Pharmaceuticals Llc
Pharmacopelia Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharmaceuticals Llc, Pharmacopelia Llc filed Critical Signal Pharmaceuticals Llc
Publication of RS51176B publication Critical patent/RS51176B/sr

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom

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  • Cardiology (AREA)
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Abstract

Jedinjenje koje ima formulu (I):ili njegova farmaceutski prihvatljiva so, gde:R1 je supstituisani ili nesupstituisani C1-6alkil, supstituisani ili nesupstituisani aril, supstituisani ili nesupstituisani C3-10cikloalkil, supstituisani ili nesupstituisani C3-10heterocikl ili supstituisani ili nesupstituisani C3-10heteroaril;R2 je H, supstituisani ili nesupstituisani C1-6alkil, supstituisani ili nesupstituisani aril, supstituisani ili nesupstituisani C3-10cikloalkil, supstituisani ili nesupstituisani C3-10heterocikl ili supstituisani ili nesupstituisani C3-10heteroaril; iR3 je aril, supstituisan sa jednim ili više halogena ili C3-10heteroaril supstituisan sa jednim ili više halogena, pri čemu je aril ili C3-10heteroaril grupa opciono dalje supstituisana sa jednom ili više C1-6alkil, hidroksil, hidroksialkil, alkoksi, alkoksialkil, amino, alkilamino, karboksi, aminokarbonil, cijano, acilamino, alkansulfonilamino, tetrazolil, triazolil ili imidazolil grupa.Prijava sadrži još 44 patentna zahteva.
RSP-2009/0402A 2005-01-13 2006-01-13 Aminopurini supstituisani haloarilom, njihove smeše i postupci lečenja pomoću njih RS51176B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64379605P 2005-01-13 2005-01-13
US70998005P 2005-08-19 2005-08-19
PCT/US2006/001275 WO2006076595A1 (en) 2005-01-13 2006-01-13 Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith

Publications (1)

Publication Number Publication Date
RS51176B true RS51176B (sr) 2010-10-31

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RSP-2009/0402A RS51176B (sr) 2005-01-13 2006-01-13 Aminopurini supstituisani haloarilom, njihove smeše i postupci lečenja pomoću njih

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US (2) US7723340B2 (sr)
EP (3) EP2289893B1 (sr)
JP (3) JP5475949B2 (sr)
KR (1) KR101294830B1 (sr)
CN (1) CN103087066A (sr)
AT (1) ATE435227T1 (sr)
AU (1) AU2006204792B2 (sr)
BR (1) BRPI0606702A2 (sr)
CA (1) CA2595182C (sr)
CY (1) CY1109306T1 (sr)
DE (1) DE602006007541D1 (sr)
DK (1) DK1838710T3 (sr)
ES (3) ES2497540T3 (sr)
HK (1) HK1136558A1 (sr)
HR (1) HRP20090383T1 (sr)
IL (2) IL184550A (sr)
MX (1) MX2007008485A (sr)
NZ (1) NZ556654A (sr)
PL (1) PL1838710T3 (sr)
PT (1) PT1838710E (sr)
RS (1) RS51176B (sr)
SI (1) SI1838710T1 (sr)
WO (1) WO2006076595A1 (sr)

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