MX2007008485A - Aminopurinas haloarilo sustituidas, composiciones de las mismas, y metodos de tratamiento con las mismas. - Google Patents

Aminopurinas haloarilo sustituidas, composiciones de las mismas, y metodos de tratamiento con las mismas.

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Publication number
MX2007008485A
MX2007008485A MX2007008485A MX2007008485A MX2007008485A MX 2007008485 A MX2007008485 A MX 2007008485A MX 2007008485 A MX2007008485 A MX 2007008485A MX 2007008485 A MX2007008485 A MX 2007008485A MX 2007008485 A MX2007008485 A MX 2007008485A
Authority
MX
Mexico
Prior art keywords
sup
compositions
methods
condition
disease
Prior art date
Application number
MX2007008485A
Other languages
English (en)
Inventor
Jonathan Wright
Adam Kois
Yoshitaka Satoh
Ronald Albers
John Sapienza
Leticia Ayala
Steven S Clareen
Maria M Delgado Mederos
Robert Hilgraf
Sayee Hedge
Kevin Hughes
Veronique Plantevin-Krenitsky
Meg Mccarrick
Lisa Nadolny
Moorthy Palanki
Kiran Sahasrabudhe
Marian Sloss
Elise Sudbeck
Ian Henderson
Andrew G Cole
Original Assignee
Signal Pharm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of MX2007008485A publication Critical patent/MX2007008485A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)

Abstract

Se proporcionan en la presente Compuestos de Aminopurina que tienen la siguiente estructura: (I) en donde R1, R2 y R3 son como se define en la presente, composiciones que comprenden una cantidad efectiva de un Compuesto de Aminopurina y metodos para tratar o prevenir el cancer, una enfermedad cardiovascular, una enfermedad renal, un padecimiento autoinmune, un padecimiento inflamatorio, degeneracion macular, dano por isquemia-reperfusion, dolor y sindromes relacionados, agotamiento relacionado con la enfermedad, un padecimiento relacionado con el asbesto, hipertension pulmonar o un padecimiento que se puede tratar o prevenir por la inhibicion de la ruta de JNK que comprende administrar una cantidad efectiva de un Compuesto de Aminopurina a un paciente en necesidad del mismo.
MX2007008485A 2005-01-13 2006-01-13 Aminopurinas haloarilo sustituidas, composiciones de las mismas, y metodos de tratamiento con las mismas. MX2007008485A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64379605P 2005-01-13 2005-01-13
US70998005P 2005-08-19 2005-08-19
PCT/US2006/001275 WO2006076595A1 (en) 2005-01-13 2006-01-13 Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith

Publications (1)

Publication Number Publication Date
MX2007008485A true MX2007008485A (es) 2007-12-07

Family

ID=36228639

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007008485A MX2007008485A (es) 2005-01-13 2006-01-13 Aminopurinas haloarilo sustituidas, composiciones de las mismas, y metodos de tratamiento con las mismas.

Country Status (23)

Country Link
US (2) US7723340B2 (es)
EP (3) EP2289893B1 (es)
JP (3) JP5475949B2 (es)
KR (1) KR101294830B1 (es)
CN (1) CN103087066A (es)
AT (1) ATE435227T1 (es)
AU (1) AU2006204792B2 (es)
BR (1) BRPI0606702A2 (es)
CA (1) CA2595182C (es)
CY (1) CY1109306T1 (es)
DE (1) DE602006007541D1 (es)
DK (1) DK1838710T3 (es)
ES (3) ES2497540T3 (es)
HK (1) HK1136558A1 (es)
HR (1) HRP20090383T1 (es)
IL (2) IL184550A (es)
MX (1) MX2007008485A (es)
NZ (1) NZ556654A (es)
PL (1) PL1838710T3 (es)
PT (1) PT1838710E (es)
RS (1) RS51176B (es)
SI (1) SI1838710T1 (es)
WO (1) WO2006076595A1 (es)

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