RS49962B - Peroralne kompozicije koje kontrolisano oslobađaju levosimendan - Google Patents

Peroralne kompozicije koje kontrolisano oslobađaju levosimendan

Info

Publication number
RS49962B
RS49962B YUP-639/00A YU63900A RS49962B RS 49962 B RS49962 B RS 49962B YU 63900 A YU63900 A YU 63900A RS 49962 B RS49962 B RS 49962B
Authority
RS
Serbia
Prior art keywords
levosimendan
controlled release
peroral compositions
release peroral
less
Prior art date
Application number
YUP-639/00A
Other languages
English (en)
Inventor
Saila Antila
Lasse Lehtonen
Ilkka Larma
Maarit Backman
Original Assignee
Orion Corporation,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8551575&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS49962(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation, filed Critical Orion Corporation,
Publication of YU63900A publication Critical patent/YU63900A/sh
Publication of RS49962B publication Critical patent/RS49962B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)

Abstract

Kompozicija za kontrolisano oslobađanje, naznačena time, što sadrži a) terapeutski efikasnu količinu levosimendana i b) komponentu koja kontroliše oslobađanje leka za obezbeđivanje oslobađanja levosimendana u toku produženog perioda vremena i stabilnog stanja nivoa u plazmi metabolita (II) od manje od 20 ng/ml, prvenstveno manje od 10 ng/ml Prijava sadrži još 8 zahteva.
YUP-639/00A 1998-04-23 1999-04-23 Peroralne kompozicije koje kontrolisano oslobađaju levosimendan RS49962B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI980901A FI980901A (fi) 1998-04-23 1998-04-23 Levosimendaania säädellysti vapauttavia oraalisia koostumuksia

Publications (2)

Publication Number Publication Date
YU63900A YU63900A (sh) 2003-07-07
RS49962B true RS49962B (sr) 2008-09-29

Family

ID=8551575

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-639/00A RS49962B (sr) 1998-04-23 1999-04-23 Peroralne kompozicije koje kontrolisano oslobađaju levosimendan

Country Status (38)

Country Link
US (1) US7045147B1 (sr)
EP (1) EP1071397B1 (sr)
JP (2) JP4566402B2 (sr)
KR (1) KR100960597B1 (sr)
CN (1) CN1248691C (sr)
AR (1) AR019096A1 (sr)
AT (1) ATE258425T1 (sr)
AU (1) AU756641B2 (sr)
BG (1) BG64839B1 (sr)
BR (1) BR9909869A (sr)
CA (1) CA2329234C (sr)
CO (1) CO5070607A1 (sr)
CZ (1) CZ295194B6 (sr)
DE (1) DE69914472T2 (sr)
DK (1) DK1071397T3 (sr)
EA (1) EA002829B1 (sr)
EE (1) EE04220B1 (sr)
ES (1) ES2215379T3 (sr)
FI (1) FI980901A (sr)
GE (1) GEP20032906B (sr)
HK (1) HK1034032A1 (sr)
HR (1) HRP20000704B1 (sr)
HU (1) HUP0101458A3 (sr)
ID (1) ID27987A (sr)
IL (2) IL138951A0 (sr)
MX (1) MXPA00010367A (sr)
NO (1) NO329809B1 (sr)
NZ (1) NZ507453A (sr)
PL (1) PL197447B1 (sr)
PT (1) PT1071397E (sr)
RS (1) RS49962B (sr)
SI (1) SI1071397T1 (sr)
SK (1) SK285427B6 (sr)
TR (1) TR200003102T2 (sr)
TW (1) TWI224507B (sr)
UA (1) UA68376C2 (sr)
WO (1) WO1999055305A2 (sr)
ZA (1) ZA200005632B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20011465A0 (fi) * 2001-07-04 2001-07-04 Orion Corp Pyridatsinonijohdannaisen uusi käyttö
BRPI0408323A (pt) * 2003-03-14 2006-03-07 Nirmal Mulye processo para a preparação de compimidos de liberação prolongada
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
CN107029220A (zh) 2008-06-30 2017-08-11 托卡根公司 5‑氟胞嘧啶制剂及其用途
JP2014172850A (ja) * 2013-03-07 2014-09-22 Capsugel Belgium Nv ハードカプセル製剤
CN105784895B (zh) * 2015-10-30 2018-05-22 成都欣捷高新技术开发有限公司 一种用高效液相色谱仪检测左西孟旦中杂质的方法
JP2023507626A (ja) 2019-12-16 2023-02-24 テナックス・セラピューティクス，インコーポレイテッド 駆出率が保たれた心不全を伴う肺高血圧症（ＰＨ－ＨＦ－ｐＥＦ）を治療するためのレボシメンダン

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ203684A (en) 1982-04-05 1986-06-11 Merck Sharp & Dohme Granular formulation for the stabilization of unstable drugs or food supplements
US4716042A (en) 1986-06-16 1987-12-29 American Home Products Corporation Stabilized coated aspirin tablets
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
US5213811A (en) * 1991-09-13 1993-05-25 Sterling Drug Inc. Oral sustained-release drug compositions
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
FI973804A (fi) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia
FI974578A (fi) * 1997-12-19 1999-06-20 Orion Yhtymae Oyj Menetelmä levosimendaanin antamiseksi
FI980902A (fi) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Levosimendaanin stabiileja koostumuksia

Also Published As

Publication number Publication date
EA002829B1 (ru) 2002-10-31
TWI224507B (en) 2004-12-01
PT1071397E (pt) 2004-06-30
HRP20000704A2 (en) 2001-04-30
ATE258425T1 (de) 2004-02-15
CN1301163A (zh) 2001-06-27
ES2215379T3 (es) 2004-10-01
HUP0101458A2 (hu) 2002-03-28
NO20005313L (no) 2000-11-21
SI1071397T1 (en) 2004-06-30
AU3524699A (en) 1999-11-16
JP2002512946A (ja) 2002-05-08
JP2010083900A (ja) 2010-04-15
BR9909869A (pt) 2000-12-19
MXPA00010367A (es) 2002-06-04
CZ295194B6 (cs) 2005-06-15
CA2329234A1 (en) 1999-11-04
DK1071397T3 (da) 2004-04-05
EE200000617A (et) 2002-06-17
IL138951A0 (en) 2001-11-25
NO329809B1 (no) 2010-12-20
HK1034032A1 (en) 2001-10-12
UA68376C2 (en) 2004-08-16
CZ20003780A3 (en) 2001-05-16
ID27987A (id) 2001-05-03
EE04220B1 (et) 2004-02-16
DE69914472D1 (de) 2004-03-04
FI980901A (fi) 1999-10-24
BG104959A (en) 2001-07-31
AU756641B2 (en) 2003-01-16
CA2329234C (en) 2008-06-10
WO1999055305A2 (en) 1999-11-04
NZ507453A (en) 2003-02-28
PL344078A1 (en) 2001-09-24
BG64839B1 (bg) 2006-06-30
US7045147B1 (en) 2006-05-16
JP4566402B2 (ja) 2010-10-20
GEP20032906B (en) 2003-02-25
SK285427B6 (sk) 2007-01-04
DE69914472T2 (de) 2004-11-11
WO1999055305A3 (en) 1999-12-29
ZA200005632B (en) 2002-01-14
TR200003102T2 (tr) 2001-02-21
AR019096A1 (es) 2001-12-26
KR100960597B1 (ko) 2010-06-07
NO20005313D0 (no) 2000-10-20
HRP20000704B1 (en) 2009-11-30
YU63900A (sh) 2003-07-07
KR20010071172A (ko) 2001-07-28
CN1248691C (zh) 2006-04-05
PL197447B1 (pl) 2008-03-31
EA200001098A1 (ru) 2001-04-23
EP1071397A2 (en) 2001-01-31
EP1071397B1 (en) 2004-01-28
HUP0101458A3 (en) 2002-05-28
CO5070607A1 (es) 2001-08-28
FI980901A0 (fi) 1998-04-23
SK15542000A3 (sk) 2001-08-06
IL138951A (en) 2006-10-31

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