RS20060157A - Method for the manufacture of thip - Google Patents

Method for the manufacture of thip

Info

Publication number
RS20060157A
RS20060157A YUP-2006/0157A YUP20060157A RS20060157A RS 20060157 A RS20060157 A RS 20060157A YU P20060157 A YUP20060157 A YU P20060157A RS 20060157 A RS20060157 A RS 20060157A
Authority
RS
Serbia
Prior art keywords
thip
acid
manufacture
relates
present
Prior art date
Application number
YUP-2006/0157A
Other languages
English (en)
Inventor
Robert Dancer
Hans Petersen
Sommer Michael Bech
Original Assignee
H.Lundbeck A/S.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58707236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS20060157(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H.Lundbeck A/S., filed Critical H.Lundbeck A/S.,
Publication of RS20060157A publication Critical patent/RS20060157A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Sadašnji pronalazak se odnosi na novi postupak pripremanja gaboksadola (THIP), koji je koristan za lečenje poremećaja sna. Posebno postupak pripremanja THIP koji se sastoji od reagovanja jedinjenja formule (8b) ili njegove soli sa kiselinom, tipično mineralnom kiselinom, da se dobije THIP kao kisela adiciona so. Sadašnji pronalazak se takođe odnosi na nekoliko intermedijarnih proizvoda.
YUP-2006/0157A 2003-09-05 2004-09-01 Method for the manufacture of thip RS20060157A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200301277 2003-09-05
PCT/DK2004/000579 WO2005023820A1 (en) 2003-09-05 2004-09-01 Method for the manufacture of thip

Publications (1)

Publication Number Publication Date
RS20060157A true RS20060157A (en) 2008-06-05

Family

ID=58707236

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2006/0157A RS20060157A (en) 2003-09-05 2004-09-01 Method for the manufacture of thip

Country Status (21)

Country Link
US (1) US7371863B2 (sr)
EP (1) EP1664060A1 (sr)
JP (1) JP4745233B2 (sr)
KR (1) KR20060069482A (sr)
CN (2) CN101497619A (sr)
AR (1) AR045540A1 (sr)
AU (1) AU2004270323B2 (sr)
BR (1) BRPI0413741A (sr)
CA (1) CA2537840C (sr)
EA (1) EA200600542A1 (sr)
HK (1) HK1096398A1 (sr)
IL (1) IL174070A (sr)
IS (1) IS8333A (sr)
ME (1) MEP1708A (sr)
MX (1) MXPA06002434A (sr)
NO (1) NO20061424L (sr)
NZ (1) NZ545178A (sr)
RS (1) RS20060157A (sr)
UA (1) UA91496C2 (sr)
WO (1) WO2005023820A1 (sr)
ZA (1) ZA200602178B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402118D0 (en) * 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
WO2005094820A1 (en) * 2004-04-02 2005-10-13 H. Lundbeck A/S Treatment of impaired respiratory function with gaboxadol
CN104974175A (zh) * 2014-04-11 2015-10-14 天津药物研究院 一种氨甲基羟异恶唑类似物的制备方法
EP3274331B1 (en) 2015-03-24 2020-02-26 H. Lundbeck A/S Manufacture of 4,5,6,7-tetrahydroisozaxolo[5,4-c]pyridin-3-ol
KR20210110585A (ko) 2018-11-21 2021-09-08 썰테고 테라퓨틱스 아이엔씨. 자살의 위험을 감소시키고 우울증의 신속한 완화를 위한 가복사돌
CN111320577B (zh) * 2018-12-13 2023-06-23 广东东阳光药业有限公司 一种吡啶酰胺的制备方法及其应用
EP4153549A2 (en) 2020-05-20 2023-03-29 Certego Therapeutics Inc. Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK270278A (da) * 1977-06-20 1978-12-21 Krogsgaard Larsen P Cycliske aminosyrer
GB2088370B (en) * 1980-11-27 1984-08-01 Kefalas As Tetrahydroisoxazolopyridine compounds
DE3145473A1 (de) * 1980-11-27 1982-08-26 Kefalas A/S, Koebenhavn-Valby 2-substituierte 4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridin-3-on-verbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4353910A (en) * 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel

Also Published As

Publication number Publication date
IL174070A0 (en) 2006-08-01
EA200600542A1 (ru) 2006-08-25
ZA200602178B (en) 2007-07-25
JP2007504179A (ja) 2007-03-01
JP4745233B2 (ja) 2011-08-10
EP1664060A1 (en) 2006-06-07
AR045540A1 (es) 2005-11-02
AU2004270323B2 (en) 2010-01-07
WO2005023820A1 (en) 2005-03-17
AU2004270323A1 (en) 2005-03-17
CN1845928A (zh) 2006-10-11
US20070112198A1 (en) 2007-05-17
NZ545178A (en) 2009-11-27
CA2537840C (en) 2011-10-25
NO20061424L (no) 2006-03-29
UA91496C2 (en) 2010-08-10
IS8333A (is) 2006-02-28
US7371863B2 (en) 2008-05-13
CN100482668C (zh) 2009-04-29
MEP1708A (xx) 2010-02-10
MXPA06002434A (es) 2006-06-20
KR20060069482A (ko) 2006-06-21
CA2537840A1 (en) 2005-03-17
HK1096398A1 (en) 2007-06-01
IL174070A (en) 2011-03-31
BRPI0413741A (pt) 2006-10-24
CN101497619A (zh) 2009-08-05

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