WO2007025696A3 - Process for making substituted piperazinyl compounds - Google Patents

Process for making substituted piperazinyl compounds Download PDF

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Publication number
WO2007025696A3
WO2007025696A3 PCT/EP2006/008401 EP2006008401W WO2007025696A3 WO 2007025696 A3 WO2007025696 A3 WO 2007025696A3 EP 2006008401 W EP2006008401 W EP 2006008401W WO 2007025696 A3 WO2007025696 A3 WO 2007025696A3
Authority
WO
WIPO (PCT)
Prior art keywords
substituted piperazinyl
compounds
making substituted
piperazinyl compounds
making
Prior art date
Application number
PCT/EP2006/008401
Other languages
French (fr)
Other versions
WO2007025696A2 (en
Inventor
Frederic Nobs
Original Assignee
Novartis Ag
Novartis Pharma Gmbh
Frederic Nobs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Pharma Gmbh, Frederic Nobs filed Critical Novartis Ag
Publication of WO2007025696A2 publication Critical patent/WO2007025696A2/en
Publication of WO2007025696A3 publication Critical patent/WO2007025696A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for making a compound of formula (I): wherein R1 is C1 to C7 alkyl. The compounds having the formula (I) may be intermediates in a process for making dipeptide compounds, for example dipeptide nitrile compounds.
PCT/EP2006/008401 2005-08-30 2006-08-28 Process for making substituted piperazinyl compounds WO2007025696A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0517637A GB0517637D0 (en) 2005-08-30 2005-08-30 Organic compounds
GB0517637.5 2005-08-30

Publications (2)

Publication Number Publication Date
WO2007025696A2 WO2007025696A2 (en) 2007-03-08
WO2007025696A3 true WO2007025696A3 (en) 2007-05-18

Family

ID=35198587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/008401 WO2007025696A2 (en) 2005-08-30 2006-08-28 Process for making substituted piperazinyl compounds

Country Status (3)

Country Link
GB (1) GB0517637D0 (en)
TW (1) TW200745071A (en)
WO (1) WO2007025696A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7543649B2 (en) 2007-01-11 2009-06-09 Rock Well Petroleum Inc. Method of collecting crude oil and crude oil collection header apparatus
US7823662B2 (en) 2007-06-20 2010-11-02 New Era Petroleum, Llc. Hydrocarbon recovery drill string apparatus, subterranean hydrocarbon recovery drilling methods, and subterranean hydrocarbon recovery methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1057818A1 (en) * 1998-01-30 2000-12-06 Meiji Seika Kaisha Ltd. PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS
WO2001058886A1 (en) * 2000-02-10 2001-08-16 Novartis Ag Dipeptide nitrile cathepsin k inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1057818A1 (en) * 1998-01-30 2000-12-06 Meiji Seika Kaisha Ltd. PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS
WO2001058886A1 (en) * 2000-02-10 2001-08-16 Novartis Ag Dipeptide nitrile cathepsin k inhibitors

Also Published As

Publication number Publication date
GB0517637D0 (en) 2005-10-05
TW200745071A (en) 2007-12-16
WO2007025696A2 (en) 2007-03-08

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