MXPA05013944A - Nuevo procedimiento para la produccion de melagatran. - Google Patents
Nuevo procedimiento para la produccion de melagatran.Info
- Publication number
- MXPA05013944A MXPA05013944A MXPA05013944A MXPA05013944A MXPA05013944A MX PA05013944 A MXPA05013944 A MX PA05013944A MX PA05013944 A MXPA05013944 A MX PA05013944A MX PA05013944 A MXPA05013944 A MX PA05013944A MX PA05013944 A MXPA05013944 A MX PA05013944A
- Authority
- MX
- Mexico
- Prior art keywords
- melagatran
- production
- new process
- formula
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Se proporciona un procedimiento para la produccion de melagatran, Formula (I) ex vivo, dicho procedimiento comprende la hidrolisis de un compuesto de la Formula II, en donde R es alquilo de 1 a 6 atomos de carbono, para formar, en una forma substancialmente libre de sal, un compuesto intermediario de la Formula II seguido por la reduccion de ese intermediario.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301879A SE0301879D0 (sv) | 2003-06-25 | 2003-06-25 | New process |
| PCT/SE2004/001016 WO2004113364A1 (en) | 2003-06-25 | 2004-06-23 | New process for the production of melagatran |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05013944A true MXPA05013944A (es) | 2006-02-24 |
Family
ID=27656614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05013944A MXPA05013944A (es) | 2003-06-25 | 2004-06-23 | Nuevo procedimiento para la produccion de melagatran. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060178312A1 (es) |
| EP (1) | EP1641814A1 (es) |
| JP (1) | JP2007536197A (es) |
| KR (1) | KR20060025569A (es) |
| CN (1) | CN1809585A (es) |
| AU (1) | AU2004249658B2 (es) |
| BR (1) | BRPI0411769A (es) |
| CA (1) | CA2528930A1 (es) |
| IL (1) | IL172287A0 (es) |
| MX (1) | MXPA05013944A (es) |
| NO (1) | NO20055925L (es) |
| SE (1) | SE0301879D0 (es) |
| WO (1) | WO2004113364A1 (es) |
| ZA (1) | ZA200510102B (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
| TW541316B (en) * | 1995-12-21 | 2003-07-11 | Astrazeneca Ab | Prodrugs of thrombin inhibitors |
-
2003
- 2003-06-25 SE SE0301879A patent/SE0301879D0/xx unknown
-
2004
- 2004-06-23 CA CA002528930A patent/CA2528930A1/en not_active Abandoned
- 2004-06-23 US US10/561,944 patent/US20060178312A1/en not_active Abandoned
- 2004-06-23 KR KR1020057024865A patent/KR20060025569A/ko not_active Application Discontinuation
- 2004-06-23 AU AU2004249658A patent/AU2004249658B2/en not_active Ceased
- 2004-06-23 CN CNA2004800175458A patent/CN1809585A/zh active Pending
- 2004-06-23 WO PCT/SE2004/001016 patent/WO2004113364A1/en active Application Filing
- 2004-06-23 BR BRPI0411769-7A patent/BRPI0411769A/pt not_active IP Right Cessation
- 2004-06-23 EP EP04749054A patent/EP1641814A1/en not_active Withdrawn
- 2004-06-23 MX MXPA05013944A patent/MXPA05013944A/es unknown
- 2004-06-23 JP JP2006517053A patent/JP2007536197A/ja active Pending
-
2005
- 2005-11-30 IL IL172287A patent/IL172287A0/en unknown
- 2005-12-12 ZA ZA200510102A patent/ZA200510102B/xx unknown
- 2005-12-13 NO NO20055925A patent/NO20055925L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0411769A (pt) | 2006-08-08 |
| IL172287A0 (en) | 2006-04-10 |
| EP1641814A1 (en) | 2006-04-05 |
| AU2004249658A1 (en) | 2004-12-29 |
| WO2004113364A1 (en) | 2004-12-29 |
| ZA200510102B (en) | 2006-11-29 |
| US20060178312A1 (en) | 2006-08-10 |
| CA2528930A1 (en) | 2004-12-29 |
| CN1809585A (zh) | 2006-07-26 |
| AU2004249658B2 (en) | 2007-02-01 |
| SE0301879D0 (sv) | 2003-06-25 |
| JP2007536197A (ja) | 2007-12-13 |
| NO20055925L (no) | 2006-01-19 |
| KR20060025569A (ko) | 2006-03-21 |
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