PT998288E - Composicoes contendo capsaicina ou analogos de capsaicina e um anestesico local - Google Patents

Composicoes contendo capsaicina ou analogos de capsaicina e um anestesico local

Info

Publication number
PT998288E
PT998288E PT98911614T PT98911614T PT998288E PT 998288 E PT998288 E PT 998288E PT 98911614 T PT98911614 T PT 98911614T PT 98911614 T PT98911614 T PT 98911614T PT 998288 E PT998288 E PT 998288E
Authority
PT
Portugal
Prior art keywords
capsaicin
site
analogues
anesthesia
pain
Prior art date
Application number
PT98911614T
Other languages
English (en)
Inventor
James N Campbell
Marco Pappagallo
Richard A Meyer
Original Assignee
James N Campbell
Richard A Meyer
Marco Pappagallo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21912426&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT998288(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by James N Campbell, Richard A Meyer, Marco Pappagallo filed Critical James N Campbell
Publication of PT998288E publication Critical patent/PT998288E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT98911614T 1997-03-13 1998-03-12 Composicoes contendo capsaicina ou analogos de capsaicina e um anestesico local PT998288E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4069797P 1997-03-13 1997-03-13

Publications (1)

Publication Number Publication Date
PT998288E true PT998288E (pt) 2002-11-29

Family

ID=21912426

Family Applications (2)

Application Number Title Priority Date Filing Date
PT01204692T PT1201241E (pt) 1997-03-13 1998-03-12 Composições contendo capsaicina ou análogos de capsaicina e um anestésico
PT98911614T PT998288E (pt) 1997-03-13 1998-03-12 Composicoes contendo capsaicina ou analogos de capsaicina e um anestesico local

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT01204692T PT1201241E (pt) 1997-03-13 1998-03-12 Composições contendo capsaicina ou análogos de capsaicina e um anestésico

Country Status (12)

Country Link
US (1) US5962532A (pt)
EP (2) EP1201241B8 (pt)
JP (1) JP2001515492A (pt)
AT (2) ATE219674T1 (pt)
AU (1) AU720859B2 (pt)
CA (1) CA2285203C (pt)
DE (2) DE69841907D1 (pt)
DK (2) DK0998288T4 (pt)
ES (2) ES2179473T5 (pt)
HK (1) HK1027759A1 (pt)
PT (2) PT1201241E (pt)
WO (1) WO1998040070A1 (pt)

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US6239180B1 (en) * 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
IL135060A (en) 1997-09-18 2005-12-18 Skyepharma Inc Sustained release liposomal anesthetic compositions and methods for the preparation thereof
JP4575592B2 (ja) 1997-11-14 2010-11-04 パシラ ファーマシューティカルズ インコーポレーテッド 多小胞リポソームの製造
SE9800139D0 (sv) 1998-01-21 1998-01-21 Astra Ab New use
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US6802841B2 (en) 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6277413B1 (en) 1998-07-17 2001-08-21 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
EP1301484A2 (en) * 2000-07-20 2003-04-16 Neurogen Corporation Capsaicin receptor ligands
US20040146590A1 (en) * 2001-03-22 2004-07-29 Iadarola Michael J Molecular neurochirurgie for pain control administering locally capsaicin or resinferatoxin
EP1395243A2 (en) * 2001-05-31 2004-03-10 SkyePharma Inc. Encapsulation of nanosuspensions in liposomes and microspheres
CA2457622A1 (en) * 2001-08-10 2003-02-20 Kava Pharmaceuticals, Inc. Kavalactone compositions and methods of use
EP1450824A4 (en) * 2001-11-02 2005-09-28 Elan Corp Plc PHARMACEUTICAL COMPOSITION
MXPA04006882A (es) * 2002-01-17 2004-12-06 Neurogen Corp Analogos substituidos de quinazolin-4-ilamina como moduladores de receptores de capsaicina.
AU2003270325A1 (en) * 2002-09-05 2004-03-29 Neurogesx, Inc. Compositions and kits for the removal of irritating compounds from bodily surfaces
US8623412B2 (en) * 2002-09-23 2014-01-07 Elan Pharma International Limited Abuse-resistant pharmaceutical compositions
US20050020690A1 (en) 2002-12-18 2005-01-27 Algorx Infiltration of capsaicin into surgical sites and open wounds
DE60322436D1 (de) * 2002-12-18 2008-09-04 Algorx Verabreichung von capsaicinoiden
EP1610742B1 (en) 2003-04-10 2015-01-21 Neurogesx, Inc. Uses and compositions for administration of capsaicin
US20060100272A1 (en) 2004-06-02 2006-05-11 Sri International Formulations for the treatment of pain
ES2355109T3 (es) 2004-12-22 2011-03-22 Mestex Ag Mezcla de un agonista de receptor de vainilloide con una sustancia inhibidora de la regeneración nerviosa, su utilización para la fabricación de un analgésico y procedimiento de aplicación de este fármaco.
JP5775246B2 (ja) 2004-12-28 2015-09-09 メステックス アクチェンゲゼルシャフトMestex Ag 関節痛を治療する薬剤を生成するためのレシニフェラトキシン(rtx)の使用方法および前記薬剤を適用する方法
ES2384244T3 (es) * 2004-12-28 2012-07-02 Mestex Ag Utilización de un agonista del receptor vaniloide juntamente con un glicosaminoglicano o un proteoglicano para la fabricación de un fármaco para el tratamiento de los dolores articulares y procedimiento para la aplicación de este fármaco
AU2006214289A1 (en) * 2005-02-14 2006-08-24 Neurogesx, Inc. Device for delivery of TRPV1 agonists
US20060222690A1 (en) * 2005-03-30 2006-10-05 Bley Keith R Low-concentration capsaicin patch and methods for treating neuropathic pain
US7771760B2 (en) * 2005-04-01 2010-08-10 Neurogesx, Inc. Oils of capsaicinoids and methods of making and using the same
US8916611B2 (en) * 2006-04-28 2014-12-23 Warsaw Orthopedic, Inc. Pharmaceutical removal of neuronal extensions from a degenerating disc
US7943666B2 (en) * 2006-07-24 2011-05-17 Trinity Laboratories, Inc. Esters of capsaicin for treating pain
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
KR101572634B1 (ko) 2008-04-04 2015-12-01 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
US8158682B2 (en) * 2008-09-12 2012-04-17 Vallinex, Inc. Instillation administration of capsaicinoids for the treatment of pain
US8987328B2 (en) * 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
WO2010129845A1 (en) * 2009-05-07 2010-11-11 University Of Cincinnati Methods of preventing ischemic injury using peripheral nociceptive stimulation
US20110135627A1 (en) * 2009-10-07 2011-06-09 The Inflasoothe Group, Inc. Pain relief composition, system and method
EP2490620A4 (en) 2009-10-23 2017-03-22 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
US8591025B1 (en) 2012-09-11 2013-11-26 Nexisvision, Inc. Eye covering and refractive correction methods for LASIK and other applications
EP2629610B1 (en) 2010-07-27 2017-09-06 Flex Pharma, Inc. Methods and compositions for preventing and relieving muscle cramps and for recovery from neuromuscular irritability and fatigue following exercise
EP2632405A4 (en) 2010-10-25 2016-02-24 Nexisvision Inc METHODS AND APPARATUSES FOR IDENTIFYING EYE RECOVERY ELEMENTS FOR SIGHT
CN103328038A (zh) 2010-12-01 2013-09-25 史拜诺莫度雷森公司 向神经解剖结构直接递送药剂
US8678584B2 (en) 2012-04-20 2014-03-25 Nexisvision, Inc. Contact lenses for refractive correction
AU2012249773A1 (en) 2011-04-28 2013-11-07 Nexisvision, Inc. Eye covering and refractive correction methods and apparatus having improved tear flow, comfort, and/or applicability
CN104010635A (zh) 2011-09-09 2014-08-27 Api起源有限责任公司 包含trpv1选择性激动剂的止痛组合物及其制备和应用
US9211274B2 (en) * 2012-02-01 2015-12-15 Warsaw Orthopedic, Inc. TRPV1 compounds in a biodegradable polymer carrier
US9465233B2 (en) 2012-04-20 2016-10-11 Nexisvision, Inc. Bimodular contact lenses
WO2013184239A1 (en) 2012-04-20 2013-12-12 Nexisvision, Inc. Contact lenses for refractive correction
US20140142073A1 (en) 2012-11-12 2014-05-22 Api Genesis, Llc Aqueous based capsaicinoid formulations and methods of manufacture and use
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US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
US20150133561A1 (en) 2013-11-12 2015-05-14 Vizuri Health Sciences Llc Aqueous based capsaicinoid formulations and methods of manufacture and use
US9341864B2 (en) 2013-11-15 2016-05-17 Nexisvision, Inc. Contact lenses having a reinforcing scaffold
WO2015116559A1 (en) 2014-01-29 2015-08-06 Nexisvision, Inc. Multifocal bimodulus contact lenses
WO2015160941A1 (en) 2014-04-15 2015-10-22 Vizuri Health Sciences Llc Topical compositions for pain relief, manufacture and use
US11634384B2 (en) 2014-11-25 2023-04-25 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
US9359316B1 (en) 2014-11-25 2016-06-07 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
US10821105B2 (en) 2016-05-25 2020-11-03 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists in combination with local anesthetics and vasoconstrictors for improved local anesthesia
JP7100635B2 (ja) 2016-11-02 2022-07-13 セントレクシオン セラピューティクス コーポレイション 安定な水性カプサイシン注射製剤およびその医学的使用
WO2018136943A1 (en) 2017-01-23 2018-07-26 Flex Pharma, Inc. Compositions and methods affecting exercise performance
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TW202019887A (zh) 2018-07-27 2020-06-01 美商同心止痛劑股份有限公司 酚系trpv1促效劑之聚乙二醇化前藥
US20210315846A1 (en) 2018-08-24 2021-10-14 Centrexion Therspeuties Corporation Capsaicin sequential dosing method for treatment of knee joint pain
US11447444B1 (en) 2019-01-18 2022-09-20 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
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Also Published As

Publication number Publication date
ES2350755T3 (es) 2011-01-26
HK1027759A1 (en) 2001-01-23
AU720859B2 (en) 2000-06-15
US5962532A (en) 1999-10-05
EP1201241B1 (en) 2010-09-22
EP1201241A3 (en) 2004-01-02
EP1201241A2 (en) 2002-05-02
EP0998288A1 (en) 2000-05-10
DE69841907D1 (de) 2010-11-04
EP0998288B2 (en) 2005-08-03
DK0998288T4 (da) 2005-08-22
DE69806246T3 (de) 2006-05-18
EP1201241B8 (en) 2010-10-27
DE69806246D1 (de) 2002-08-01
ATE219674T1 (de) 2002-07-15
ES2179473T5 (es) 2006-03-01
DK1201241T3 (da) 2010-12-13
DE69806246T2 (de) 2003-02-06
JP2001515492A (ja) 2001-09-18
WO1998040070A1 (en) 1998-09-17
CA2285203A1 (en) 1998-09-17
CA2285203C (en) 2005-07-26
EP0998288B1 (en) 2002-06-26
ES2179473T3 (es) 2003-01-16
AU6553298A (en) 1998-09-29
DK0998288T3 (da) 2002-10-14
PT1201241E (pt) 2010-12-02
ATE481970T1 (de) 2010-10-15

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