PT93375A - Processo para a preparacao de diois de esteroides e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de diois de esteroides e de composicoes farmaceuticas que os contem Download PDF

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Publication number
PT93375A
PT93375A PT93375A PT9337590A PT93375A PT 93375 A PT93375 A PT 93375A PT 93375 A PT93375 A PT 93375A PT 9337590 A PT9337590 A PT 9337590A PT 93375 A PT93375 A PT 93375A
Authority
PT
Portugal
Prior art keywords
general formula
hydrogen
formula
water
process according
Prior art date
Application number
PT93375A
Other languages
English (en)
Portuguese (pt)
Inventor
Laszlo Szporny
Csaba Molnar
Gyorgy Hajos
Jozsef Toth
Arpad Kiraly
Anna Boor-Nee-Mezei
Janos Csorgei
Krisztina Szekely
Lilla Forgacs
Gyorgy Fekete
Bulcsu Herenyi
Sandor Holly
Jozsef Szunyog
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of PT93375A publication Critical patent/PT93375A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT93375A 1989-03-09 1990-03-08 Processo para a preparacao de diois de esteroides e de composicoes farmaceuticas que os contem PT93375A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU891156A HU203562B (en) 1989-03-09 1989-03-09 Process for producing new steroide diols and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
PT93375A true PT93375A (pt) 1990-11-07

Family

ID=10953088

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93375A PT93375A (pt) 1989-03-09 1990-03-08 Processo para a preparacao de diois de esteroides e de composicoes farmaceuticas que os contem

Country Status (17)

Country Link
US (1) US5082835A (forum.php)
EP (1) EP0387091A3 (forum.php)
JP (1) JPH06104679B2 (forum.php)
KR (1) KR930009445B1 (forum.php)
CN (1) CN1045396A (forum.php)
AR (1) AR244700A1 (forum.php)
AU (1) AU623503B2 (forum.php)
CA (1) CA2011282A1 (forum.php)
EG (1) EG19411A (forum.php)
FI (1) FI901199A7 (forum.php)
HU (1) HU203562B (forum.php)
IL (1) IL93478A (forum.php)
IN (1) IN170846B (forum.php)
NO (1) NO177147C (forum.php)
PH (1) PH26676A (forum.php)
PT (1) PT93375A (forum.php)
ZA (1) ZA901752B (forum.php)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
AU2006239221C1 (en) 2005-04-28 2012-08-16 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
CN110078785A (zh) * 2019-06-04 2019-08-02 博诺康源(北京)药业科技有限公司 一种布地奈德杂质ep-ze的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3167545A (en) * 1959-02-07 1965-01-26 Syntex Corp 16beta-methyl-16alpha, 17 alpha-dihydroxy pregnenes and the 16alpha, 17alpha-cyclic ketals and acetals thereof
US3345362A (en) * 1961-07-27 1967-10-03 Lilly Co Eli Novel pregnenolone acetonides
US4036831A (en) * 1975-10-28 1977-07-19 Steroid Development Company Establishment Trimethyl siloxane steroid intermediates
JP2604842B2 (ja) * 1987-08-14 1997-04-30 ジ・アップジョン・カンパニー 改良された９α‐脱ハロゲン化方法

Also Published As

Publication number Publication date
AR244700A1 (es) 1993-11-30
PH26676A (en) 1992-09-15
FI901199A7 (fi) 1990-09-10
IL93478A (en) 1994-11-11
IL93478A0 (en) 1990-11-29
NO901103L (no) 1990-09-10
EP0387091A3 (en) 1992-05-06
HU203562B (en) 1991-08-28
NO901103D0 (no) 1990-03-08
AU623503B2 (en) 1992-05-14
AU5110290A (en) 1990-09-13
JPH06104679B2 (ja) 1994-12-21
CA2011282A1 (en) 1990-09-09
EP0387091A2 (en) 1990-09-12
KR900014422A (ko) 1990-10-23
NO177147C (no) 1995-07-26
US5082835A (en) 1992-01-21
JPH02279695A (ja) 1990-11-15
FI901199A0 (fi) 1990-03-09
KR930009445B1 (ko) 1993-10-04
IN170846B (forum.php) 1992-05-30
NO177147B (no) 1995-04-18
CN1045396A (zh) 1990-09-19
EG19411A (en) 1995-01-31
ZA901752B (en) 1991-05-29

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19951206