PT923568E - Novas benzofuran-4-carboxamidas - Google Patents

Novas benzofuran-4-carboxamidas

Info

Publication number
PT923568E
PT923568E PT97942858T PT97942858T PT923568E PT 923568 E PT923568 E PT 923568E PT 97942858 T PT97942858 T PT 97942858T PT 97942858 T PT97942858 T PT 97942858T PT 923568 E PT923568 E PT 923568E
Authority
PT
Portugal
Prior art keywords
carboxamides
new benzofuran
benzofuran
new
substituted
Prior art date
Application number
PT97942858T
Other languages
English (en)
Portuguese (pt)
Inventor
Hans-Peter Kley
Christian Schudt
Rolf Beume
Dietrich Hafner
Ulrich Thibaut
Wolf-Rudiger Ulrich
Dieter Flockerzi
Beate Schmidt
Armin Hatzelmann
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT923568E publication Critical patent/PT923568E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
PT97942858T 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas PT923568E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19

Publications (1)

Publication Number Publication Date
PT923568E true PT923568E (pt) 2003-04-30

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97942858T PT923568E (pt) 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas

Country Status (11)

Country Link
US (1) US6211203B1 (Direct)
EP (1) EP0923568B9 (Direct)
JP (1) JP4309475B2 (Direct)
AT (1) ATE229516T1 (Direct)
AU (1) AU4454597A (Direct)
CY (1) CY2458B1 (Direct)
DE (1) DE69717827T2 (Direct)
DK (1) DK0923568T5 (Direct)
ES (1) ES2188983T4 (Direct)
PT (1) PT923568E (Direct)
WO (1) WO1998007715A1 (Direct)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1219171A (zh) * 1996-05-20 1999-06-09 达尔文发现有限公司 苯并呋喃甲酰胺及其治疗用途
WO1999040085A1 (en) * 1998-02-09 1999-08-12 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
ATE245642T1 (de) 1998-06-10 2003-08-15 Altana Pharma Ag Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
JP2002529444A (ja) * 1998-11-12 2002-09-10 アリアド・ファーマシューティカルズ・インコーポレイテッド 二環式シグナル伝達阻害剤、それを含む組成物とその用途
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
AU777012B2 (en) 1999-08-21 2004-09-30 Takeda Gmbh Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
AP2011005613A0 (en) 2008-09-11 2011-04-30 Pfizer Heteroaryls amide derivatives and their use as glucokinase activators.
AR074760A1 (es) 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
UA99882C2 (uk) * 2009-03-11 2012-10-10 Пфайзер Інк. Похідні бензофуранілу, фармацевтична композиція та спосіб лікування захворювань (варіанти)
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
JP5746334B2 (ja) * 2010-06-16 2015-07-08 シマベイ セラピューティクス， インコーポレーテッド Ｇｐｒ１２０受容体作動薬及びその使用
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
MX395591B (es) * 2017-11-10 2025-03-25 Jiangsu Hengrui Medicine Co Metodo para preparar derivado de benzofurano

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1046939C (zh) * 1993-07-02 1999-12-01 比克·古尔顿·劳姆贝尔格化学公司 氟烷氧基取代的苯甲酰胺类及其制备方法和应用
KR100381584B1 (ko) * 1994-07-22 2003-08-21 알타나 파마 아게 디히드로벤조푸란
PT771794E (pt) * 1995-05-19 2006-09-29 Kyowa Hakko Kogyo Kk Compostos heterociclicos contendo oxigenio
DE69620458T2 (de) * 1995-12-05 2002-10-02 Darwin Discovery Ltd., Cambridge Benzofuran-carboxamide und -sulfonamide
CN1219171A (zh) * 1996-05-20 1999-06-09 达尔文发现有限公司 苯并呋喃甲酰胺及其治疗用途

Also Published As

Publication number Publication date
JP4309475B2 (ja) 2009-08-05
JP2000516932A (ja) 2000-12-19
CY2458B1 (en) 2005-06-03
EP0923568B9 (en) 2003-08-13
EP0923568A1 (en) 1999-06-23
DE69717827D1 (de) 2003-01-23
ES2188983T3 (es) 2003-07-01
WO1998007715A9 (en) 1999-04-29
EP0923568B1 (en) 2002-12-11
WO1998007715A1 (en) 1998-02-26
ATE229516T1 (de) 2002-12-15
DK0923568T3 (da) 2003-04-07
DE69717827T2 (de) 2003-09-04
DK0923568T5 (da) 2003-11-03
US6211203B1 (en) 2001-04-03
ES2188983T4 (es) 2004-06-01
AU4454597A (en) 1998-03-06

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