PT920410E - Preparacao de derivados de carboxilato de ciclo-hexeno - Google Patents

Preparacao de derivados de carboxilato de ciclo-hexeno

Info

Publication number
PT920410E
PT920410E PT97939508T PT97939508T PT920410E PT 920410 E PT920410 E PT 920410E PT 97939508 T PT97939508 T PT 97939508T PT 97939508 T PT97939508 T PT 97939508T PT 920410 E PT920410 E PT 920410E
Authority
PT
Portugal
Prior art keywords
preparation
carboxylate derivatives
cyclohexene carboxylate
useful
formulas
Prior art date
Application number
PT97939508T
Other languages
English (en)
Inventor
John C Rohloff
Choung U Kim
Matthew A Williams
Kenneth M Kent
Lawrence R Mcgee
John D Munger
Ernest J Prisbe
Michael J Postich
Daphne E Kelly
Lijun Zhang
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/701,942 external-priority patent/US5859284A/en
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of PT920410E publication Critical patent/PT920410E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/26Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT97939508T 1996-08-23 1997-08-22 Preparacao de derivados de carboxilato de ciclo-hexeno PT920410E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2412296P 1996-08-23 1996-08-23
US08/701,942 US5859284A (en) 1996-08-23 1996-08-23 Preparation of carbocyclic compounds

Publications (1)

Publication Number Publication Date
PT920410E true PT920410E (pt) 2002-07-31

Family

ID=26698076

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97939508T PT920410E (pt) 1996-08-23 1997-08-22 Preparacao de derivados de carboxilato de ciclo-hexeno

Country Status (12)

Country Link
EP (1) EP0920410B1 (pt)
JP (3) JP3622983B2 (pt)
AT (1) ATE215062T1 (pt)
AU (1) AU738577C (pt)
DE (1) DE69711395T2 (pt)
DK (1) DK0920410T3 (pt)
ES (1) ES2173480T3 (pt)
HK (1) HK1021815A1 (pt)
MX (1) MXPA99001697A (pt)
NZ (2) NZ507106A (pt)
PT (1) PT920410E (pt)
WO (1) WO1998007685A1 (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69607704T2 (de) 1995-02-27 2000-12-28 Gilead Sciences Inc Neue selektive inhibitoren viraler oder bakterieller neuraminidasen
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5859284A (en) 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US5994377A (en) 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
NZ502988A (en) * 1997-09-17 2002-08-28 Gilead Sciences Inc 5-Acetamido-4-amino-2-propionyloxy-6-isopropoxy-1-cyclohexene useful for treating influenza
US6455571B1 (en) 1998-04-23 2002-09-24 Abbott Laboratories Inhibitors of neuraminidases
US6518305B1 (en) 1998-04-23 2003-02-11 Abbott Laboratories Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
ATE209621T1 (de) * 1998-05-13 2001-12-15 Hoffmann La Roche Verfahren zur herstellung von shikiminsäure und deren derivate
EP1059283B1 (en) * 1999-06-11 2003-05-28 F. Hoffmann-La Roche Ag Process for preparing neuraminidase inhibitor ro-64-0796
US6593314B1 (en) 1999-10-19 2003-07-15 Abbott Laboratories Neuraminidase inhibitors
AU2039301A (en) * 1999-10-19 2001-04-30 Abbott Laboratories Neuraminidase inhibitors
JP2001131144A (ja) 1999-11-02 2001-05-15 Sagami Chem Res Center 7−アザビシクロ[4.1.0]ヘプト−3−エン−3−カルボン酸エステル類の製造方法
US6462226B1 (en) 1999-12-03 2002-10-08 Hoffmann-La Roche Inc. Process for the preparation of 4,5-diamino shikimic acid derivatives
US6797832B1 (en) 1999-12-27 2004-09-28 Sagami Chemical Research Center Process for the production of 5-oxy-7-oxabicyclo [4.1.0] hept-3-ene-3-carboxylic acid esters
US6403824B2 (en) 2000-02-22 2002-06-11 Hoffmann-La Roche Inc. Process for the preparation for 4,5-diamino shikimic acid derivatives
US6518048B2 (en) 2000-04-10 2003-02-11 Hoffmann-La Roche Inc. Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
US7122684B2 (en) 2003-03-13 2006-10-17 Roche Colorado Corporation Process for preparing 1,2-diamino compounds
RS51073B (sr) 2003-12-23 2010-10-31 Tibotec Pharmaceuticals Ltd. Proces za pripremanje (3r,3as,6ar)-heksahidrofuro│2,3-b│ furan-3-il (1s,2r)-3-││(4-aminofenil) sulfonil│(izobutil) amino │-1-benzil-2-hidroksipropilkarbamata
MX2007002316A (es) 2004-09-02 2007-04-17 Hoffmann La Roche Proceso para preparacion de acido 4,5-diamino shikimico.
PL1951654T3 (pl) * 2005-11-25 2011-11-30 Hetero Drugs Ltd Ulepszony sposób wytwarzania fosforanu oseltamiwiru
EP2178819A2 (en) 2005-12-28 2010-04-28 F.Hoffmann-La Roche Ag Epoxide intermediate in the tamiflu synthesis
US7732632B2 (en) 2006-01-02 2010-06-08 Hetero Drugs Limited Process for obtaining pure oseltamivir
EP1987825B1 (en) 2006-02-20 2018-09-05 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition comprising oseltamivir phosphate
JP2008050336A (ja) * 2006-07-28 2008-03-06 Univ Of Tokyo イソキヌクリジン誘導体およびこれを利用した1−シクロヘキセン−1−カルボン酸誘導体の製法
WO2009037137A2 (en) 2007-09-18 2009-03-26 F. Hoffmann-La Roche Ag Process from shikimic acid to oseltamivir phosphate
US8334319B2 (en) * 2008-01-04 2012-12-18 Roche Palo Alto Llc Polymorphic forms of oseltamivir phosphate
TWI482775B (zh) 2008-09-01 2015-05-01 Tibotec Pharm Ltd 用於製備(3r,3as,6ar)-六氫呋喃并〔2,3-b〕呋喃-3-基(1s,2r)-3-〔〔(4-胺基苯基)磺醯基〕(異丁基)胺基〕-1-苯甲基-2-羥基丙基胺基甲酸酯之方法
JP5698128B2 (ja) 2009-06-09 2015-04-08 国立大学法人 岡山大学 ジヒドロキシヘキセン酸エステル及びその製造方法
JP4496351B1 (ja) * 2009-09-01 2010-07-07 国立大学法人 岡山大学 1,3−ジオキソラン化合物及びその製造方法
SK288218B6 (sk) 2010-05-05 2014-08-05 Synkola, S.R.O. Spôsob prípravy 1-nitro-4-oxobutanylamidov a ich opačných enantiomérov
JP5039236B1 (ja) 2011-04-27 2012-10-03 学校法人東邦大学 抗不整脈剤及び心房細動抑制剤
WO2014208753A1 (ja) * 2013-06-28 2014-12-31 富士フイルム株式会社 シキミ酸誘導体の製造法および中間体
TWI481600B (zh) * 2013-07-24 2015-04-21 Nat Applied Res Laboratories 一種奎尼酸衍生物、其製程及其用途
CN105439884A (zh) * 2015-10-27 2016-03-30 沈阳药科大学 一种奥司他韦的制备方法
CN110272381A (zh) * 2019-06-19 2019-09-24 五邑大学 含吡啶片段的奥司他韦类似物及其应用
JP7475578B2 (ja) 2020-07-01 2024-04-30 信越化学工業株式会社 1,3-ジヒドロキシ-1,1,3,3-テトラ-tert-ブトキシジシロキサンの製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69607704T2 (de) * 1995-02-27 2000-12-28 Gilead Sciences Inc Neue selektive inhibitoren viraler oder bakterieller neuraminidasen

Also Published As

Publication number Publication date
NZ507106A (en) 2003-01-31
HK1021815A1 (en) 2000-10-05
JP2003002888A (ja) 2003-01-08
WO1998007685A1 (en) 1998-02-26
DE69711395D1 (de) 2002-05-02
AU4157997A (en) 1998-03-06
DK0920410T3 (da) 2002-06-10
MXPA99001697A (es) 2004-04-05
EP0920410B1 (en) 2002-03-27
JP2000517306A (ja) 2000-12-26
ES2173480T3 (es) 2002-10-16
NZ522535A (en) 2004-07-30
ATE215062T1 (de) 2002-04-15
JP2009167210A (ja) 2009-07-30
JP3622983B2 (ja) 2005-02-23
AU738577B2 (en) 2001-09-20
AU738577C (en) 2002-04-11
EP0920410A1 (en) 1999-06-09
DE69711395T2 (de) 2002-11-07

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