PT88448A - Process for preparing antiprotozoal pharmaceutical compositionscontaining azithromycin or a derivative thereof - Google Patents

Process for preparing antiprotozoal pharmaceutical compositionscontaining azithromycin or a derivative thereof

Info

Publication number
PT88448A
PT88448A PT88448A PT8844888A PT88448A PT 88448 A PT88448 A PT 88448A PT 88448 A PT88448 A PT 88448A PT 8844888 A PT8844888 A PT 8844888A PT 88448 A PT88448 A PT 88448A
Authority
PT
Portugal
Prior art keywords
azithromycin
derivative
preparing
antiprotozoal
sec
Prior art date
Application number
PT88448A
Other languages
English (en)
Other versions
PT88448B (pt
Inventor
Jack Samuel Remington
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT88448A publication Critical patent/PT88448A/pt
Publication of PT88448B publication Critical patent/PT88448B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT88448A 1987-09-10 1988-09-07 Processo para a preparacao de composicoes farmaceuticas antiprotozoarias contendo azitromicina ou um seu derivado PT88448B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002317 WO1989002271A1 (en) 1987-09-10 1987-09-10 Azithromycin and derivatives as antiprotozoal agents

Publications (2)

Publication Number Publication Date
PT88448A true PT88448A (pt) 1989-07-31
PT88448B PT88448B (pt) 1992-10-30

Family

ID=22202554

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88448A PT88448B (pt) 1987-09-10 1988-09-07 Processo para a preparacao de composicoes farmaceuticas antiprotozoarias contendo azitromicina ou um seu derivado

Country Status (18)

Country Link
US (1) US4963531A (pt)
EP (1) EP0307128B1 (pt)
JP (1) JPH0667847B2 (pt)
KR (1) KR930011996B1 (pt)
AT (1) ATE74508T1 (pt)
AU (1) AU596029B2 (pt)
CA (1) CA1334574C (pt)
DE (1) DE3869880D1 (pt)
DK (1) DK175544B1 (pt)
HU (1) HUT47553A (pt)
IE (1) IE61507B1 (pt)
IL (1) IL87698A (pt)
MY (1) MY103388A (pt)
NZ (1) NZ226112A (pt)
PH (1) PH26229A (pt)
PT (1) PT88448B (pt)
WO (1) WO1989002271A1 (pt)
ZA (1) ZA886727B (pt)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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UA27040C2 (uk) 1987-07-09 2000-02-28 Пфайзер Інк. Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
TW271400B (pt) * 1992-07-30 1996-03-01 Pfizer
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US5529994A (en) * 1993-05-05 1996-06-25 Palo Alto Medical Foundation Treatment for toxoplasmosis
WO1994025038A1 (en) * 1993-05-05 1994-11-10 Palo Alto Medical Foundation Use of rifamycin derivatives for the manufacture of a medicament for the treatment of toxoplasmosis
US5795871A (en) * 1994-04-26 1998-08-18 Nobuhiro Narita Pharmaceutical composition for treatment of non-small cell lung cancer
AU744318B2 (en) * 1994-04-29 2002-02-21 Pfizer Inc. Method of administering azithromycin
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
RO114740B1 (ro) * 1994-05-06 1999-07-30 Pfizer Compozitie cu eliberare controlata, procedeu de obtinere a acesteia si metoda de tratament
US20030212123A1 (en) * 1997-05-05 2003-11-13 Pfizer Inc. COX-2 selective carprofen for treating pain and inflammation in dogs
US6407074B1 (en) * 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
JP2003512290A (ja) * 1997-09-10 2003-04-02 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての８ａ−アザライド
PT1437359E (pt) * 1997-10-16 2007-04-30 Glaxosmithkline Zagreb Novos 3,6-hemicetais da classe dos 9a-azalidos
CN1273142C (zh) * 1998-11-30 2006-09-06 特瓦制药工业有限公司 阿齐霉素的乙醇化物,制备方法以及医药组合物
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
IT1313610B1 (it) 1999-08-09 2002-09-09 S I F I Societa Ind Farmaceuti Processo per la preparazione di formulazioni acquose per uso oftalmico
US6608033B1 (en) 1999-08-27 2003-08-19 Pfizer Inc. Treatment or prevention of coccidiosis
PT1246831E (pt) 2000-01-04 2008-03-28 Teva Pharma Método de preparação de di-hidrato de azitromicina
WO2002007736A1 (en) * 2000-07-24 2002-01-31 Cadila Pharmaceuticals Limited The process for manufacturing of clear liquid pharmaceutical composition of azithromycin
ATE320441T1 (de) 2000-07-25 2006-04-15 Silanes Sa De Cv Lab Einstufiges verfahren zur herstellung von 7,16-
WO2002009640A2 (en) * 2000-08-01 2002-02-07 Shiva Prasad Singh Process for the preparation of anhydrous azithromycin
DE60114028T2 (de) 2000-08-23 2006-07-13 Wockhardt Ltd. Verfahren zur herstellung von wasserfreiem azithromycin
US6949519B2 (en) * 2000-11-27 2005-09-27 Sandoz Ag Macrolide solvates
KR100491183B1 (ko) * 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
NZ529118A (en) 2001-05-22 2005-10-28 Pfizer Prod Inc Crystal forms of azithromycin
US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
EP1671979B1 (en) 2001-05-22 2008-08-13 Pfizer Products Inc. New Cristal Form of Azithromycin
EA200400214A1 (ru) * 2001-08-21 2004-06-24 Пфайзер Продактс Инк. Азитромицин в виде разовой дозы
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
DE60232005D1 (de) * 2001-10-18 2009-05-28 Teva Pharma Stabilisierte azithromycin-zusammensetzungen
NZ532707A (en) * 2001-12-21 2006-07-28 Pfizer Prod Inc Directly compressible formulations of azithromycin
IL161259A0 (en) * 2001-12-21 2004-09-27 Pfizer Prod Inc Methods for wet granulating azithromycin
NZ534234A (en) * 2002-02-01 2007-05-31 Pfizer Prod Inc Dry granulated formulations of non-dihydrate form of azithromycin
ES2220229B1 (es) * 2003-05-29 2005-10-16 Quimica Sintetica, S.A. Sales de adicion de azitromicina y acido citrico y procedimiento para su obtencion.
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
EP1689368B1 (en) 2003-12-04 2016-09-28 Bend Research, Inc Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions
CA2547597A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
CN1889931A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 利用挤压器制备优选含泊洛沙姆和甘油酯的多重粒子阿奇霉素组合物的喷雾－冻凝方法
CN1889932A (zh) 2003-12-04 2007-01-03 辉瑞产品公司 制备药用多颗粒的方法
MXPA06005913A (es) * 2003-12-04 2006-06-27 Pfizer Prod Inc Formas de dosificacion de multiparticulas de azitromicina por procedimientos basados en liquidos.
CN1295719C (zh) * 2003-12-30 2007-01-17 郑玉庆 远程智能型变压器
WO2006115494A1 (en) * 2005-04-26 2006-11-02 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
US20060198895A1 (en) * 2005-03-07 2006-09-07 Kotliar Eleonora M Azithromycin powder for oral suspension compositions
CN100427499C (zh) * 2005-12-20 2008-10-22 山东诚创医药技术开发有限公司 一种阿奇霉素的可溶性盐及其制备方法
WO2013088274A1 (en) 2011-12-14 2013-06-20 Wockhardt Limited Anhydrous amorphous azithromycin composition free of azithromycin dihydrate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
ZA835204B (en) * 1982-07-19 1985-02-27 Pfizer N-methyl 11-aza-10-deoxo-10-dihydroerythromycin a,intermediates therefor and processes for their preparation
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
AU8280087A (en) * 1987-09-10 1989-04-17 Pfizer Inc. Azithromycin and derivatives as antiprotozoal agents

Also Published As

Publication number Publication date
AU596029B2 (en) 1990-04-12
IE882762L (en) 1989-03-10
JPH0283326A (ja) 1990-03-23
EP0307128A3 (en) 1990-07-04
PT88448B (pt) 1992-10-30
JPH0667847B2 (ja) 1994-08-31
ZA886727B (en) 1990-04-25
NZ226112A (en) 1997-03-24
PH26229A (en) 1992-04-01
US4963531A (en) 1990-10-16
EP0307128B1 (en) 1992-04-08
DK502888A (da) 1989-03-13
CA1334574C (en) 1995-02-28
AU2206188A (en) 1989-05-11
KR890004709A (ko) 1989-05-09
IL87698A (en) 1992-12-01
DK502888D0 (da) 1988-09-09
IL87698A0 (en) 1989-02-28
DE3869880D1 (de) 1992-05-14
MY103388A (en) 1993-06-30
KR930011996B1 (ko) 1993-12-23
ATE74508T1 (de) 1992-04-15
IE61507B1 (en) 1994-11-02
EP0307128A2 (en) 1989-03-15
DK175544B1 (da) 2004-11-29
WO1989002271A1 (en) 1989-03-23
HUT47553A (en) 1989-03-28

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920407

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20080907