DK336688A - Nucleosider od fremgangsmaade til fremstilling deraf - Google Patents

Nucleosider od fremgangsmaade til fremstilling deraf

Info

Publication number
DK336688A
DK336688A DK336688A DK336688A DK336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A
Authority
DK
Denmark
Prior art keywords
nucleosides
preparing
procedure
infections
dideoxynucleosides
Prior art date
Application number
DK336688A
Other languages
English (en)
Other versions
DK336688D0 (da
Inventor
Samuel Broder
Hiroaki Mitsuya
Steve Tam
Manfred Weigele
Original Assignee
Hoffmann La Roche
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Us Health filed Critical Hoffmann La Roche
Publication of DK336688D0 publication Critical patent/DK336688D0/da
Publication of DK336688A publication Critical patent/DK336688A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK336688A 1987-06-22 1988-06-20 Nucleosider od fremgangsmaade til fremstilling deraf DK336688A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/064,631 US4837311A (en) 1987-06-22 1987-06-22 Anti-retroviral compounds

Publications (2)

Publication Number Publication Date
DK336688D0 DK336688D0 (da) 1988-06-20
DK336688A true DK336688A (da) 1988-12-23

Family

ID=22057259

Family Applications (1)

Application Number Title Priority Date Filing Date
DK336688A DK336688A (da) 1987-06-22 1988-06-20 Nucleosider od fremgangsmaade til fremstilling deraf

Country Status (6)

Country Link
US (1) US4837311A (da)
EP (1) EP0296573B1 (da)
JP (1) JPH02262587A (da)
AT (1) ATE100098T1 (da)
DE (1) DE3887014T2 (da)
DK (1) DK336688A (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187163A (en) * 1987-03-27 1993-02-16 Baker Norton Pharmaceuticals, Inc. Anti-viral compounds, dosage forms and methods
ZA886890B (en) * 1987-10-09 1989-05-30 Hoffmann La Roche Novel dideoxycytidine derivatives
FR2631964B1 (fr) * 1988-05-31 1990-09-07 Pasteur Institut Glucosyl phosphotriesters de derives de thymidine ayant une activite contre les retrovirus
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
US5824796A (en) * 1988-09-28 1998-10-20 Epoch Pharmaceuticals, Inc. Cross-linking oligonucleotides
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
USRE38416E1 (en) 1988-09-28 2004-02-03 Epoch Biosciences, Inc. Cross-linking oligonucleotides
GR1000618B (el) * 1989-03-17 1992-08-31 Oncogen Μεθοδος αναστολης hiv χρησιμοποιωντας συνεργιστικους συνδυασμους νουκλεοσιδικων παραγωγων.
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
WO1990014353A1 (en) * 1989-05-18 1990-11-29 Microprobe Corporation Crosslinking oligonucleotides
EP0537299A1 (en) * 1990-03-29 1993-04-21 Gilead Sciences, Inc. Oligonucleotide-transport agent disulfide conjugates
US5430138A (en) * 1990-07-27 1995-07-04 Chiron Corporation Hydroxyl-protecting groups attached to cytidine nucleotide compounds which are orthogonally removable
US5561225A (en) * 1990-09-19 1996-10-01 Southern Research Institute Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages
GB9104740D0 (en) * 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
EP0577725A4 (en) * 1991-03-29 1996-04-17 Univ Florida Targeted drug delivery via mixed phosphate derivatives
DE550714T1 (de) * 1991-06-21 1995-06-14 Acic Canada Inc Antiviralverbindungen und Ihrer Verfahren zur Herstellung.
US6136601A (en) * 1991-08-21 2000-10-24 Epoch Pharmaceuticals, Inc. Targeted mutagenesis in living cells using modified oligonucleotides
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
WO1999028308A1 (en) * 1997-11-29 1999-06-10 Truett William L Antibiotics and process for preparation
MXPA04007402A (es) 2002-02-01 2005-06-17 Ariad Gene Therapeutics Inc Compuestos que contienen fosforo y usos de los mismos.
IL149298A0 (en) * 2002-04-23 2002-11-10 Lycored Natural Prod Ind Ltd Tomato product and method for obtaining same
PL377287A1 (pl) * 2002-12-12 2006-01-23 Idenix (Cayman) Limited Sposób wytwarzania 2'-rozgałęzionych nukleozydów

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3650492T2 (de) * 1985-03-16 1996-10-31 The Wellcome Foundation Ltd., London Therapeutische Nukleoside
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
DE3689976T2 (de) * 1985-05-15 1995-03-16 Wellcome Found Therapeutische Nucleoside und deren Herstellung.
DK167377B1 (da) * 1985-09-17 1993-10-25 Wellcome Found 3'-azidopyrimidinnucleosider eller farmaceutisk acceptable salte eller estere deraf til anvendelse ved behandling af eller profylakse for en human retrovirusinfektion
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods

Also Published As

Publication number Publication date
EP0296573B1 (en) 1994-01-12
EP0296573A3 (en) 1990-07-04
EP0296573A2 (en) 1988-12-28
ATE100098T1 (de) 1994-01-15
DE3887014T2 (de) 1994-05-19
DK336688D0 (da) 1988-06-20
US4837311A (en) 1989-06-06
JPH02262587A (ja) 1990-10-25
DE3887014D1 (de) 1994-02-24

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment