PT86660A - Process for preparing adenosine 5:-carboxamide derivatives - Google Patents

Process for preparing adenosine 5:-carboxamide derivatives

Info

Publication number
PT86660A
PT86660A PT86660A PT8666088A PT86660A PT 86660 A PT86660 A PT 86660A PT 86660 A PT86660 A PT 86660A PT 8666088 A PT8666088 A PT 8666088A PT 86660 A PT86660 A PT 86660A
Authority
PT
Portugal
Prior art keywords
carboxamide derivatives
preparing adenosine
adenosine
preparing
carboxamide
Prior art date
Application number
PT86660A
Other languages
English (en)
Other versions
PT86660B (pt
Inventor
Alan J Hutchison
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT86660A publication Critical patent/PT86660A/pt
Publication of PT86660B publication Critical patent/PT86660B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT86660A 1987-02-04 1988-01-29 Processo para a preparacao de derivados de adenosina-5'-carboxamida PT86660B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1116987A 1987-02-04 1987-02-04

Publications (2)

Publication Number Publication Date
PT86660A true PT86660A (pt) 1988-02-01
PT86660B PT86660B (pt) 1992-02-28

Family

ID=21749163

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86660A PT86660B (pt) 1987-02-04 1988-01-29 Processo para a preparacao de derivados de adenosina-5'-carboxamida

Country Status (13)

Country Link
EP (1) EP0277917A3 (pt)
JP (1) JPS63201196A (pt)
KR (1) KR880009984A (pt)
AU (1) AU1123388A (pt)
DD (1) DD284679A5 (pt)
DK (1) DK54488A (pt)
FI (1) FI880405A (pt)
HU (1) HU199155B (pt)
IE (1) IE880293L (pt)
NO (1) NO880469L (pt)
PT (1) PT86660B (pt)
YU (1) YU20288A (pt)
ZA (1) ZA88755B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
GR1000138B (el) * 1987-04-06 1991-09-27 Sandoz Ag Νεα παραγωγα ριβοφουρανουρονικου οξεος, μεθοδος δια την παρασευη αυτων και η χρησιμοποιησις αυτων.
LU87181A1 (fr) * 1987-04-06 1988-11-17 Sandoz Sa Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments
US5034381A (en) * 1988-01-07 1991-07-23 Ciba-Geigy Corporation 2-(substituted amino) adenosines as antihypertensives
US4977144A (en) * 1988-08-02 1990-12-11 Ciba-Geigy Corporation Imidazo[4,5-b]pyridine derivatives as cardiovascular agents
AU3820989A (en) * 1988-08-02 1990-02-08 Ciba-Geigy Ag 7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
US5312961A (en) * 1989-02-14 1994-05-17 Elf Sanofi 2-amino-7-hydroxytetralin carboxylalkyl ethers
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
EP0550631B1 (en) * 1990-09-25 1997-01-02 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
US5189027A (en) 1990-11-30 1993-02-23 Yamasa Shoyu Kabushiki Kaisha 2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases
EP0499755A1 (fr) * 1991-02-18 1992-08-26 MIDY S.p.A. Nouvelles phényléthanolaminotétralines, procédé pour leur préparation, intermédiaires dans ce procédé et compositions pharmaceutiques les contenant
GB9111580D0 (en) * 1991-05-30 1991-07-24 Wellcome Found Nucleoside derivative
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
GB9414193D0 (en) * 1994-07-14 1994-08-31 Glaxo Group Ltd Compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
HUP0103025A3 (en) 1998-06-23 2002-04-29 Glaxo Group Ltd A2a agonist 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives, medicaments containing the same, process for producing them and the useful intermediates
US7414036B2 (en) 2002-01-25 2008-08-19 Muscagen Limited Compounds useful as A3 adenosine receptor agonists
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
JP5011112B2 (ja) * 2004-09-20 2012-08-29 イノテック ファーマシューティカルズ コーポレイション プリン誘導体を含有する炎症性疾患の治療用医薬
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1019727A (en) * 1971-03-18 1977-10-25 Abbott Laboratories Adenosine-5'-carboxylic acid amides
US4501735A (en) * 1983-12-05 1985-02-26 Warner-Lambert Company N6-(1- and 2-benzocycloalkyl) adenosines
LU87181A1 (fr) * 1987-04-06 1988-11-17 Sandoz Sa Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments

Also Published As

Publication number Publication date
NO880469D0 (no) 1988-02-03
DD284679A5 (de) 1990-11-21
ZA88755B (en) 1989-10-25
KR880009984A (ko) 1988-10-06
FI880405A0 (fi) 1988-01-29
AU1123388A (en) 1988-08-18
HUT46334A (en) 1988-10-28
NO880469L (no) 1988-08-05
DK54488D0 (da) 1988-02-03
JPS63201196A (ja) 1988-08-19
IE880293L (en) 1988-08-04
HU199155B (en) 1990-01-29
YU20288A (en) 1990-04-30
PT86660B (pt) 1992-02-28
FI880405A (fi) 1988-08-05
EP0277917A3 (en) 1990-03-28
EP0277917A2 (en) 1988-08-10
DK54488A (da) 1988-08-05

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19910808

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930228