PT82635B - Processo para a preparacao de uma composicao de libertacao controlada de uma droga macromolecular e respectivo metodo de tratamento com a referida composicao - Google Patents
Processo para a preparacao de uma composicao de libertacao controlada de uma droga macromolecular e respectivo metodo de tratamento com a referida composicaoInfo
- Publication number
- PT82635B PT82635B PT82635A PT8263586A PT82635B PT 82635 B PT82635 B PT 82635B PT 82635 A PT82635 A PT 82635A PT 8263586 A PT8263586 A PT 8263586A PT 82635 B PT82635 B PT 82635B
- Authority
- PT
- Portugal
- Prior art keywords
- composition
- preparation
- treatment
- macromolecular drug
- controlled liberation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/07—Microporous membranes
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Extrusion Moulding Of Plastics Or The Like (AREA)
- Fluid-Pressure Circuits (AREA)
- Developing Agents For Electrophotography (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/737,629 US4666704A (en) | 1985-05-24 | 1985-05-24 | Controlled release delivery system for macromolecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT82635A PT82635A (en) | 1986-06-01 |
| PT82635B true PT82635B (pt) | 1988-07-29 |
Family
ID=24964638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT82635A PT82635B (pt) | 1985-05-24 | 1986-05-23 | Processo para a preparacao de uma composicao de libertacao controlada de uma droga macromolecular e respectivo metodo de tratamento com a referida composicao |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4666704A (pt) |
| EP (1) | EP0204476B1 (pt) |
| JP (1) | JP2755298B2 (pt) |
| KR (1) | KR940000001B1 (pt) |
| CN (1) | CN1020851C (pt) |
| AT (1) | ATE78155T1 (pt) |
| AU (1) | AU590565B2 (pt) |
| CA (1) | CA1277237C (pt) |
| DE (1) | DE3685992T2 (pt) |
| DK (1) | DK171758B1 (pt) |
| ES (1) | ES8707666A1 (pt) |
| IE (1) | IE59684B1 (pt) |
| IL (1) | IL78895A (pt) |
| PT (1) | PT82635B (pt) |
| ZA (1) | ZA863867B (pt) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4786501A (en) * | 1985-07-15 | 1988-11-22 | International Minerals & Chemical Corp. | Cylindrical implants for the controlled release of growth hormones |
| GB8521494D0 (en) * | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
| IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
| AU601443B2 (en) * | 1986-05-16 | 1990-09-13 | Monash Medical Centre | Biocompatible implants |
| US5342622A (en) * | 1986-05-16 | 1994-08-30 | The State Of Victoria | Subdermal biocompatible implants |
| WO1987006828A1 (en) * | 1986-05-16 | 1987-11-19 | The State Of Victoria | Biocompatible implants |
| US4761289A (en) * | 1986-10-10 | 1988-08-02 | International Minerals & Chemical Corp. | Sustained release implant and method for preparing same |
| US4863736A (en) * | 1987-03-16 | 1989-09-05 | Monsanto Company | Somatotropin prolonged release |
| GB2209937B (en) * | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
| US5073381A (en) * | 1988-08-15 | 1991-12-17 | University Of Akron | Amphiphilic networks |
| SE8803822D0 (sv) * | 1988-10-26 | 1988-10-26 | Novel dosage form | |
| US5108756A (en) * | 1989-01-12 | 1992-04-28 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| US5030452A (en) * | 1989-01-12 | 1991-07-09 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| US5141748A (en) * | 1989-02-17 | 1992-08-25 | Hoffmann-La Roche, Inc. | Implant drug delivery device |
| ES2042292T3 (es) * | 1989-03-17 | 1993-12-01 | Pitman-Moore, Inc. | Dispositivo de administracion de proteinas macromoleculares por liberacion controlada. |
| US5225205A (en) * | 1989-07-28 | 1993-07-06 | Debiopharm S.A. | Pharmaceutical composition in the form of microparticles |
| US5439688A (en) * | 1989-07-28 | 1995-08-08 | Debio Recherche Pharmaceutique S.A. | Process for preparing a pharmaceutical composition |
| CH679207A5 (pt) * | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
| GB8928250D0 (en) * | 1989-12-14 | 1990-02-21 | Erba Carlo Spa | Use of supercritical fluids to obtain porous sponges of biodegradable polymers |
| CA2050067C (en) * | 1990-08-30 | 2000-05-30 | Yasushi Morita | Controlled drug release composition |
| IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| CH683149A5 (fr) * | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
| US5516522A (en) * | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
| US5660848A (en) * | 1994-11-02 | 1997-08-26 | The Population Council, Center For Biomedical Research | Subdermally implantable device |
| GB2295316B (en) * | 1994-11-25 | 1997-09-10 | William Leslie Porter | Bolus for supplying biologically beneficial substances to ruminant animals |
| US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| US7550005B2 (en) * | 1995-06-07 | 2009-06-23 | Cook Incorporated | Coated implantable medical device |
| US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| US7896914B2 (en) * | 1995-06-07 | 2011-03-01 | Cook Incorporated | Coated implantable medical device |
| SE505146C2 (sv) * | 1995-10-19 | 1997-06-30 | Biogram Ab | Partiklar för fördröjd frisättning |
| US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
| US20060025726A1 (en) * | 1996-06-04 | 2006-02-02 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with pharmacologically active layer |
| US20060030826A1 (en) * | 1996-06-04 | 2006-02-09 | Vance Products Incorporated,d/b/a Cook Urological Incorporated | Implantable medical device with anti-neoplastic drug |
| US6022554A (en) * | 1997-12-15 | 2000-02-08 | American Home Products Corporation | Polymeric microporous film coated subcutaneous implant |
| KR20000022894A (ko) * | 1998-09-05 | 2000-04-25 | 이승진 | 생분해성 고분자 미립자형 제제 및 그 제조방법 |
| US6730349B2 (en) | 1999-04-19 | 2004-05-04 | Scimed Life Systems, Inc. | Mechanical and acoustical suspension coating of medical implants |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| AU2000255261A1 (en) * | 2000-05-26 | 2001-12-11 | C.T.P. Cable Technology Procurement Ag | Means for maintenance and/or correction of glucose concentration in blood |
| US7803149B2 (en) | 2002-07-12 | 2010-09-28 | Cook Incorporated | Coated medical device |
| WO2003000156A1 (en) * | 2001-06-22 | 2003-01-03 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
| US8750983B2 (en) | 2004-09-20 | 2014-06-10 | P Tech, Llc | Therapeutic system |
| PL1824460T3 (pl) * | 2004-11-10 | 2015-09-30 | Tolmar Therapeutics Inc | Stabilizowany polimerowy układ dostarczania |
| US8128952B2 (en) * | 2005-01-12 | 2012-03-06 | Clemson University Research Foundation | Ligand-mediated controlled drug delivery |
| US20070141106A1 (en) * | 2005-10-19 | 2007-06-21 | Bonutti Peter M | Drug eluting implant |
| US20070106271A1 (en) * | 2005-11-09 | 2007-05-10 | Searete Llc, A Limited Liability Corporation | Remote control of substance delivery system |
| US8475829B2 (en) * | 2006-04-06 | 2013-07-02 | Nupathe Inc. | Implants for the treatment of dopamine associated states |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| US20210007973A1 (en) * | 2016-10-05 | 2021-01-14 | Titan Pharmaceuticals, Inc. | Implantable devices for drug delivery with reduced burst release |
| AU2018345844B2 (en) | 2017-10-06 | 2024-03-07 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| US12364792B2 (en) | 2018-01-08 | 2025-07-22 | Foundry Therapeutics, Inc. | Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents |
| AU2019270779B2 (en) | 2018-05-12 | 2024-08-01 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| KR20210013088A (ko) * | 2018-05-24 | 2021-02-03 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| KR20210013089A (ko) * | 2018-05-24 | 2021-02-03 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2987445A (en) * | 1958-10-10 | 1961-06-06 | Rohm & Haas | Drug composition |
| US3538214A (en) * | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
| DE2010416B2 (de) * | 1970-03-05 | 1979-03-29 | Hoechst Ag, 6000 Frankfurt | Oral anwendbare Arzneiform mit Retardwirkung |
| AR206692A1 (es) * | 1972-12-27 | 1976-08-13 | Alza Corp | Agente dispensador de liberacion sostenida de substancias activas |
| US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
| US3923939A (en) * | 1974-06-07 | 1975-12-02 | Alza Corp | Process for improving release kinetics of a monolithic drug delivery device |
| US4391797A (en) * | 1977-01-05 | 1983-07-05 | The Children's Hospital Medical Center | Systems for the controlled release of macromolecules |
| US4127127A (en) * | 1977-05-23 | 1978-11-28 | Alza Corporation | Therapeutic systems made from certain segmented copolyesters |
| US4148871A (en) * | 1977-10-11 | 1979-04-10 | Pitt Colin G | Sustained subdermal delivery ofdrugs using poly(ε-caprolactone) and its copolymers |
| IN152178B (pt) * | 1978-05-08 | 1983-11-05 | Pfizer | |
| DD146547A5 (de) * | 1978-07-15 | 1981-02-18 | Boehringer Sohn Ingelheim | Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen |
| EP0013131A3 (en) * | 1978-12-27 | 1981-01-07 | Mundipharma A.G. | Pharmaceutical composition in solid dosage form, and process for its production |
| JPS593962B2 (ja) * | 1980-06-24 | 1984-01-27 | 日東電工株式会社 | 徐放性酵素製剤 |
| JPS593963B2 (ja) * | 1980-06-24 | 1984-01-27 | 日東電工株式会社 | 徐放性酵素製剤 |
| PH19942A (en) * | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
| US4377568A (en) * | 1981-08-12 | 1983-03-22 | Merck Sharp & Dohme (I.A.) Corp. | Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same |
-
1985
- 1985-05-24 US US06/737,629 patent/US4666704A/en not_active Expired - Lifetime
-
1986
- 1986-05-20 AU AU57672/86A patent/AU590565B2/en not_active Ceased
- 1986-05-22 JP JP61116301A patent/JP2755298B2/ja not_active Expired - Lifetime
- 1986-05-23 DK DK243886A patent/DK171758B1/da not_active IP Right Cessation
- 1986-05-23 IL IL78895A patent/IL78895A/xx not_active IP Right Cessation
- 1986-05-23 ES ES555277A patent/ES8707666A1/es not_active Expired
- 1986-05-23 KR KR1019860004040A patent/KR940000001B1/ko not_active Expired - Fee Related
- 1986-05-23 CA CA000509864A patent/CA1277237C/en not_active Expired - Lifetime
- 1986-05-23 DE DE8686303949T patent/DE3685992T2/de not_active Expired - Lifetime
- 1986-05-23 IE IE137086A patent/IE59684B1/en not_active IP Right Cessation
- 1986-05-23 AT AT86303949T patent/ATE78155T1/de not_active IP Right Cessation
- 1986-05-23 EP EP86303949A patent/EP0204476B1/en not_active Expired - Lifetime
- 1986-05-23 ZA ZA863867A patent/ZA863867B/xx unknown
- 1986-05-23 PT PT82635A patent/PT82635B/pt not_active IP Right Cessation
- 1986-05-24 CN CN86104226A patent/CN1020851C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3685992D1 (de) | 1992-08-20 |
| DK243886A (da) | 1986-11-25 |
| DE3685992T2 (de) | 1992-12-24 |
| JP2755298B2 (ja) | 1998-05-20 |
| JPS61277629A (ja) | 1986-12-08 |
| AU590565B2 (en) | 1989-11-09 |
| US4666704A (en) | 1987-05-19 |
| AU5767286A (en) | 1986-11-27 |
| EP0204476A1 (en) | 1986-12-10 |
| PT82635A (en) | 1986-06-01 |
| ATE78155T1 (de) | 1992-08-15 |
| CN1020851C (zh) | 1993-05-26 |
| IL78895A0 (en) | 1986-09-30 |
| EP0204476B1 (en) | 1992-07-15 |
| KR940000001B1 (ko) | 1994-01-05 |
| CA1277237C (en) | 1990-12-04 |
| ES555277A0 (es) | 1987-08-16 |
| DK243886D0 (da) | 1986-05-23 |
| IE861370L (en) | 1986-11-24 |
| ES8707666A1 (es) | 1987-08-16 |
| KR860008776A (ko) | 1986-12-18 |
| IL78895A (en) | 1991-01-31 |
| ZA863867B (en) | 1987-01-28 |
| DK171758B1 (da) | 1997-05-12 |
| CN86104226A (zh) | 1987-02-25 |
| IE59684B1 (en) | 1994-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010731 |