PT762896E - Composicoes de tocoferol para administracao de agentes biologicamente activos - Google Patents
Composicoes de tocoferol para administracao de agentes biologicamente activosInfo
- Publication number
- PT762896E PT762896E PT95921750T PT95921750T PT762896E PT 762896 E PT762896 E PT 762896E PT 95921750 T PT95921750 T PT 95921750T PT 95921750 T PT95921750 T PT 95921750T PT 762896 E PT762896 E PT 762896E
- Authority
- PT
- Portugal
- Prior art keywords
- compositions
- administration
- biologically active
- active agents
- tocoferol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Fodder In General (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9409778A GB9409778D0 (en) | 1994-05-16 | 1994-05-16 | Compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
PT762896E true PT762896E (pt) | 2003-01-31 |
Family
ID=10755206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95921750T PT762896E (pt) | 1994-05-16 | 1995-05-15 | Composicoes de tocoferol para administracao de agentes biologicamente activos |
Country Status (13)
Country | Link |
---|---|
US (1) | US6193985B1 (pt) |
EP (1) | EP0762896B1 (pt) |
AT (1) | ATE223232T1 (pt) |
CA (1) | CA2189328C (pt) |
DE (1) | DE69528057T2 (pt) |
DK (1) | DK0762896T3 (pt) |
ES (1) | ES2178674T3 (pt) |
FI (1) | FI119175B (pt) |
GB (1) | GB9409778D0 (pt) |
NO (1) | NO314569B1 (pt) |
NZ (1) | NZ287857A (pt) |
PT (1) | PT762896E (pt) |
WO (1) | WO1995031217A1 (pt) |
Families Citing this family (115)
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CN1129400A (zh) * | 1994-05-06 | 1996-08-21 | 阿尔康实验室公司 | 维生素e生育酚衍生物在眼科组合物中的应用 |
GB2317562B (en) * | 1995-07-20 | 1999-08-18 | Danbiosyst Uk | Lipid vehicle drug delivery composition containing vitamin E |
GB9514878D0 (en) * | 1995-07-20 | 1995-09-20 | Danbiosyst Uk | Vitamin E as a solubilizer for drugs contained in lipid vehicles |
US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
ES2118033B1 (es) * | 1996-02-16 | 1999-07-01 | Bial Ind Farmaceutica S A | Formulacion farmaceutica antiinflamatoria. |
AP1150A (en) * | 1996-03-22 | 2003-03-14 | Glaxo Group Ltd | Compositions comprising an HIV protease inhibitor such as Vx 478 and a water soluble vitamin E compound such as vitamin E-TPGS. |
US6730679B1 (en) | 1996-03-22 | 2004-05-04 | Smithkline Beecham Corporation | Pharmaceutical formulations |
KR100472581B1 (ko) * | 1996-03-22 | 2005-06-16 | 글락소 그룹 리미티드 | Vx478과같은hiv프로테아제억제제및비타민e-tpgs와같은수용성비타민e화합물을포함하는조성물 |
MY126358A (en) * | 1996-03-22 | 2006-09-29 | Glaxo Group Ltd | Compositions comprising vx478 and a water soluble tocopherol derivative such as vitamin e-tpgs |
US6284794B1 (en) * | 1996-11-05 | 2001-09-04 | Head Explorer Aps | Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase |
US6458373B1 (en) | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
US6727280B2 (en) | 1997-01-07 | 2004-04-27 | Sonus Pharmaceuticals, Inc. | Method for treating colorectal carcinoma using a taxane/tocopherol formulation |
CA2286052A1 (en) * | 1997-04-17 | 1998-10-29 | Lise Sylvest Nielsen | A novel bioadhesive drug delivery system based on liquid crystals |
US20040141923A1 (en) * | 1997-10-01 | 2004-07-22 | Dugger Harry A. | Buccal, polar and non-polar spray containing alprazolam |
US7632517B2 (en) | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
US20040136914A1 (en) | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
AU735084B2 (en) * | 1998-02-09 | 2001-06-28 | Joel Bolonick | Treatment of chronic inflammatory disorders of the gastrointestinal tract |
US7030155B2 (en) | 1998-06-05 | 2006-04-18 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
US8466134B1 (en) * | 1998-06-26 | 2013-06-18 | Athena Neurosciences, Inc. | Aqueous compositions containing corticosteroids for nasal and pulmonary delivery |
US5869704A (en) * | 1998-08-24 | 1999-02-09 | Eastman Chemical Company | Water-dispersible or water-soluble D-tocotrienol compounds and methods for making therefor |
KR20010073232A (ko) * | 1998-11-20 | 2001-07-31 | 추후제출 | 분산성 인지질로 안정화된 마이크로입자 |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
BR0014320A (pt) | 1999-09-27 | 2002-05-28 | Sonus Pharma Inc | Composições de substâncias terapêuticas solúveis em tocol |
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US6610271B2 (en) * | 2000-05-10 | 2003-08-26 | University Of Kentucky Research Foundation | System and method for intranasal administration of lorazepam |
US20040115133A1 (en) * | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
US20060083691A1 (en) * | 2000-05-10 | 2006-04-20 | Wermeling Daniel P | Intranasal opioid compositions, delivery devices and methods of using same |
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NL7711916A (nl) | 1977-10-29 | 1979-05-02 | Akzo Nv | Werkwijze ter bereiding van sterk geconcen- treerde farmaceutische preparaten van steroiden. |
US4439432A (en) | 1982-03-22 | 1984-03-27 | Peat Raymond F | Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols |
DE3405240A1 (de) | 1984-02-15 | 1985-08-22 | Roshdy Dipl.-Chem. Dr. 5000 Köln Ismail | Rheuma- und venenmittel |
GB8501015D0 (en) | 1985-01-16 | 1985-02-20 | Riker Laboratories Inc | Drug |
US4628052A (en) * | 1985-05-28 | 1986-12-09 | Peat Raymond F | Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities |
ATE60226T1 (de) | 1986-03-10 | 1991-02-15 | Kurt Burghart | Pharmazeutikum sowie verfahren zu seiner herstellung. |
AU620048B2 (en) | 1987-09-03 | 1992-02-13 | University Of Georgia Research Foundation, Inc., The | Ocular cyclosporin composition |
DE3883246T2 (de) * | 1987-10-19 | 1993-12-02 | Liposome Co Inc | Auf tocopherol basierte arzneimittelsysteme. |
MX9203804A (es) * | 1987-10-19 | 1992-07-01 | Liposome Co Inc | Sistemas farmaceuticos a base de tocoferol. |
US4847072A (en) * | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising tocopherol sorbate |
US4960814A (en) | 1988-06-13 | 1990-10-02 | Eastman Kodak Company | Water-dispersible polymeric compositions |
US4950664A (en) | 1988-09-16 | 1990-08-21 | Rugby-Darby Group Companies, Inc. | Nasal administration of benzodiazepine hypnotics |
DE3908047A1 (de) | 1989-03-13 | 1990-09-20 | Desitin Arzneimittel Gmbh | Hochdisperse pharmazeutische zusammensetzung |
AU653325B2 (en) | 1990-02-12 | 1994-09-29 | Lucky Limited | A composition durably releasing bioactive polypeptides |
DE69029909T2 (de) | 1990-03-28 | 1997-09-11 | Noven Pharma | Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut |
WO1991016929A1 (en) | 1990-05-10 | 1991-11-14 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
US5179122A (en) * | 1991-02-11 | 1993-01-12 | Eastman Kodak Company | Nutritional supplement containing vitamin e |
US5223268A (en) | 1991-05-16 | 1993-06-29 | Sterling Drug, Inc. | Low solubility drug-coated bead compositions |
EP0636618A1 (de) | 1991-06-04 | 1995-02-01 | Marigen S.A. | Spontan dispergierbare Konzentrate und Mikroemulsionen mit Vitamin-E-Verbindungen zur Herstellung von Arzneimitteln mit Antitumoraler Wirksamkeit |
WO1993003720A2 (en) | 1991-08-16 | 1993-03-04 | Trevithick John R | Methods and compositions for treating sunburns |
AU658681B2 (en) | 1991-10-23 | 1995-04-27 | Block Drug Company Inc., The | Penetration enhancement of topically applied formulations |
IL101387A (en) | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
EP0648113A4 (en) | 1992-04-23 | 1996-12-04 | Berlex Lab | BIOADHAESIVE FIXED MINERAL OIL EMULSION. |
JP2811036B2 (ja) | 1992-05-26 | 1998-10-15 | 参天製薬株式会社 | ビタミンe点眼剤 |
CN1118575A (zh) * | 1993-03-03 | 1996-03-13 | 藤泽药品工业株式会社 | 旋光异构化抑制剂 |
DE4322826A1 (de) | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
WO1995011039A1 (de) * | 1993-10-22 | 1995-04-27 | Hexal Pharma Gmbh | Pharmazeutische zusammensetzung mit cyclosporin a und alpha-tocopherol |
KR970701535A (ko) | 1994-03-14 | 1997-04-12 | 지울리아노 페트렐리 | 비타민 E를 함유하는 에어로졸 약물 제형(Aerosol drug formulations containing vitamin'E) |
US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
CN1129400A (zh) | 1994-05-06 | 1996-08-21 | 阿尔康实验室公司 | 维生素e生育酚衍生物在眼科组合物中的应用 |
-
1994
- 1994-05-16 GB GB9409778A patent/GB9409778D0/en active Pending
-
1995
- 1995-05-15 NZ NZ287857A patent/NZ287857A/xx not_active IP Right Cessation
- 1995-05-15 ES ES95921750T patent/ES2178674T3/es not_active Expired - Lifetime
- 1995-05-15 WO PCT/EP1995/001835 patent/WO1995031217A1/en active IP Right Grant
- 1995-05-15 AT AT95921750T patent/ATE223232T1/de active
- 1995-05-15 DK DK95921750T patent/DK0762896T3/da active
- 1995-05-15 CA CA002189328A patent/CA2189328C/en not_active Expired - Fee Related
- 1995-05-15 DE DE69528057T patent/DE69528057T2/de not_active Expired - Lifetime
- 1995-05-15 PT PT95921750T patent/PT762896E/pt unknown
- 1995-05-15 EP EP95921750A patent/EP0762896B1/en not_active Expired - Lifetime
-
1996
- 1996-11-14 NO NO19964832A patent/NO314569B1/no not_active IP Right Cessation
- 1996-11-15 FI FI964583A patent/FI119175B/fi not_active IP Right Cessation
-
1997
- 1997-05-14 US US08/856,054 patent/US6193985B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69528057T2 (de) | 2003-11-06 |
DE69528057D1 (de) | 2002-10-10 |
AU697540B2 (en) | 1998-10-08 |
US6193985B1 (en) | 2001-02-27 |
FI964583A0 (fi) | 1996-11-15 |
AU2670595A (en) | 1995-12-05 |
EP0762896A1 (en) | 1997-03-19 |
WO1995031217A1 (en) | 1995-11-23 |
EP0762896B1 (en) | 2002-09-04 |
ATE223232T1 (de) | 2002-09-15 |
NO314569B1 (no) | 2003-04-14 |
NZ287857A (en) | 1998-09-24 |
FI119175B (fi) | 2008-08-29 |
DK0762896T3 (da) | 2003-01-06 |
FI964583A (fi) | 1996-11-15 |
GB9409778D0 (en) | 1994-07-06 |
CA2189328C (en) | 2003-07-22 |
CA2189328A1 (en) | 1995-11-23 |
ES2178674T3 (es) | 2003-01-01 |
NO964832D0 (no) | 1996-11-14 |
NO964832L (no) | 1997-01-13 |
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