PT71913B - Process for the preparation of derivatives of benzodiazepine with pharmaceutical compounds - Google Patents
Process for the preparation of derivatives of benzodiazepine with pharmaceutical compoundsInfo
- Publication number
- PT71913B PT71913B PT71913A PT7191380A PT71913B PT 71913 B PT71913 B PT 71913B PT 71913 A PT71913 A PT 71913A PT 7191380 A PT7191380 A PT 7191380A PT 71913 B PT71913 B PT 71913B
- Authority
- PT
- Portugal
- Prior art keywords
- benzodiazepine
- derivatives
- preparation
- pharmaceutical compounds
- pharmaceutical
- Prior art date
Links
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7935846 | 1979-10-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT71913A PT71913A (en) | 1980-11-01 |
| PT71913B true PT71913B (en) | 1981-08-31 |
Family
ID=10508540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT71913A PT71913B (en) | 1979-10-16 | 1980-10-14 | Process for the preparation of derivatives of benzodiazepine with pharmaceutical compounds |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US4404137A (en, 2012) |
| EP (1) | EP0027390B1 (en, 2012) |
| JP (1) | JPS5663987A (en, 2012) |
| KR (2) | KR850000471B1 (en, 2012) |
| AR (2) | AR228041A1 (en, 2012) |
| AT (1) | AT373889B (en, 2012) |
| AU (1) | AU538500B2 (en, 2012) |
| BE (1) | BE885729A (en, 2012) |
| BG (2) | BG35042A3 (en, 2012) |
| CA (1) | CA1159056A (en, 2012) |
| CH (1) | CH646700A5 (en, 2012) |
| CS (1) | CS244409B2 (en, 2012) |
| DD (1) | DD153692A5 (en, 2012) |
| DE (1) | DE3068706D1 (en, 2012) |
| DK (1) | DK437480A (en, 2012) |
| ES (1) | ES8106905A1 (en, 2012) |
| FI (1) | FI67550C (en, 2012) |
| FR (1) | FR2467851A1 (en, 2012) |
| GB (1) | GB8327127D0 (en, 2012) |
| GR (1) | GR70720B (en, 2012) |
| HU (1) | HU182213B (en, 2012) |
| IE (1) | IE50358B1 (en, 2012) |
| IL (1) | IL61264A (en, 2012) |
| IT (1) | IT1143047B (en, 2012) |
| LU (1) | LU82853A1 (en, 2012) |
| MX (1) | MX6233E (en, 2012) |
| NZ (1) | NZ195248A (en, 2012) |
| PH (2) | PH16288A (en, 2012) |
| PL (2) | PL126824B1 (en, 2012) |
| PT (1) | PT71913B (en, 2012) |
| RO (2) | RO81351B (en, 2012) |
| YU (1) | YU261580A (en, 2012) |
| ZA (1) | ZA806342B (en, 2012) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404137A (en) * | 1979-10-16 | 1983-09-13 | Lilly Industries Limited | Pyrazolo [3,4-b][1,5]benzodiazepine compounds |
| US4431589A (en) * | 1980-12-11 | 1984-02-14 | Lilly House | Benzodiazepine compounds and their use as pharmaceuticals |
| US4596799A (en) * | 1985-01-29 | 1986-06-24 | Ciba-Geigy Corporation | 9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines |
| TW219896B (en, 2012) * | 1988-07-07 | 1994-02-01 | Duphar Int Res | |
| GB8819059D0 (en) * | 1988-08-11 | 1988-09-14 | Lilly Industries Ltd | Benzodiazepine compounds & their use as pharmaceuticals |
| US5631250A (en) * | 1995-03-24 | 1997-05-20 | Eli Lilly And Company | Process and solvate of 2-methyl-thieno-benzodiazepine |
| US5637584A (en) * | 1995-03-24 | 1997-06-10 | Eli Lilly And Company | Solvate of olanzapine |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| AU2004206931A1 (en) * | 2003-01-23 | 2004-08-05 | Acadia Pharmaceuticals Inc. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| JP2007534656A (ja) * | 2003-12-22 | 2007-11-29 | アカディア ファーマシューティカルズ，インコーポレーテッド | ムスカリンアゴニストとしてのアミノ置換ジアリール［ａ，ｄ］シクロヘプテン類似体および精神神経疾患の治療方法 |
| KR20070007888A (ko) * | 2004-04-01 | 2007-01-16 | 아카디아 파마슈티칼스 인코포레이티드 | 결정질 ｎ-데스메틸클로자핀 |
| WO2007053618A1 (en) * | 2005-10-31 | 2007-05-10 | Acadia Pharmaceuticals Inc. | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| JP5438482B2 (ja) * | 2009-12-03 | 2014-03-12 | Ｊｕｋｉ株式会社 | ミシン、ミシンの縫製データ編集装置及びミシンの縫製データ編集プログラム |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3450694A (en) * | 1966-02-23 | 1969-06-17 | Abbott Lab | Substituted benzoxazepines and benzothiazepines |
| US3758479A (en) * | 1967-03-22 | 1973-09-11 | Sandoz Ag | Nitro and sulphamoyl substituted dibenzodiazepines |
| DE1795183B1 (de) * | 1968-08-20 | 1972-07-20 | Thomae Gmbh Dr K | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel |
| CA918659A (en) * | 1969-07-31 | 1973-01-09 | Yoshitomi Pharmaceutical Industries | 11-(4-substituted-1-piperazinyl)-dibenzo (b,f) (1,4) thiazepines |
| US4115568A (en) * | 1974-11-26 | 1978-09-19 | Lilly Industries Limited | Thieno[3,2-b]-[1,5]benzodiazepines |
| US4172831A (en) * | 1974-11-26 | 1979-10-30 | Lilly Industries Limited | Thieno-benzodiazepines |
| US3951981A (en) * | 1975-02-24 | 1976-04-20 | American Cyanamid Company | Substituted benzodiazepines and method of use |
| US3953430A (en) * | 1975-02-24 | 1976-04-27 | American Cyanamid Company | Substituted benzodiazepin-10-ones and method of use |
| DE2707269A1 (de) * | 1977-02-19 | 1978-08-24 | Hoechst Ag | Heterocyclische stickstoffverbindungen und verfahren zu ihrer herstellung |
| DE2707270A1 (de) * | 1977-02-19 | 1978-08-24 | Hoechst Ag | Pyrazolo-diazepine und verfahren zu ihrer herstellung |
| US4097597A (en) * | 1977-02-23 | 1978-06-27 | Abbott Laboratories | Dibenzo b,e! 1,4!diazepines |
| IT7851496A0 (it) * | 1977-10-31 | 1978-10-13 | Sandoz Ag | Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica |
| CH643263A5 (de) * | 1979-05-11 | 1984-05-30 | Sandoz Ag | Benzodiazepine, ihre herstellung und verwendung. |
| EP0023707B1 (de) * | 1979-08-03 | 1986-04-30 | Byk Gulden Lomberg Chemische Fabrik GmbH | Substituierte Tetraazatricyclen, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel |
| US4404137A (en) * | 1979-10-16 | 1983-09-13 | Lilly Industries Limited | Pyrazolo [3,4-b][1,5]benzodiazepine compounds |
-
1980
- 1980-10-02 US US06/193,200 patent/US4404137A/en not_active Expired - Lifetime
- 1980-10-11 GR GR63138A patent/GR70720B/el unknown
- 1980-10-13 YU YU02615/80A patent/YU261580A/xx unknown
- 1980-10-13 RO RO102349A patent/RO81351B/ro unknown
- 1980-10-13 IL IL61264A patent/IL61264A/xx unknown
- 1980-10-13 PH PH24717A patent/PH16288A/en unknown
- 1980-10-13 FR FR8021823A patent/FR2467851A1/fr active Granted
- 1980-10-13 CS CS806938A patent/CS244409B2/cs unknown
- 1980-10-13 RO RO108967A patent/RO85822B/ro unknown
- 1980-10-13 MX MX809093U patent/MX6233E/es unknown
- 1980-10-13 NZ NZ195248A patent/NZ195248A/xx unknown
- 1980-10-14 AT AT0510180A patent/AT373889B/de not_active IP Right Cessation
- 1980-10-14 IT IT49899/80A patent/IT1143047B/it active
- 1980-10-14 CA CA000362328A patent/CA1159056A/en not_active Expired
- 1980-10-14 AU AU63252/80A patent/AU538500B2/en not_active Ceased
- 1980-10-14 PT PT71913A patent/PT71913B/pt unknown
- 1980-10-14 CH CH763980A patent/CH646700A5/fr not_active IP Right Cessation
- 1980-10-15 ES ES495948A patent/ES8106905A1/es not_active Expired
- 1980-10-15 PL PL1980227306A patent/PL126824B1/pl unknown
- 1980-10-15 DE DE8080303649T patent/DE3068706D1/de not_active Expired
- 1980-10-15 DD DD80224618A patent/DD153692A5/de unknown
- 1980-10-15 IE IE2135/80A patent/IE50358B1/en unknown
- 1980-10-15 BG BG057344A patent/BG35042A3/xx unknown
- 1980-10-15 LU LU82853A patent/LU82853A1/fr unknown
- 1980-10-15 KR KR1019800003960A patent/KR850000471B1/ko not_active Expired
- 1980-10-15 JP JP14423180A patent/JPS5663987A/ja active Pending
- 1980-10-15 EP EP80303649A patent/EP0027390B1/en not_active Expired
- 1980-10-15 FI FI803253A patent/FI67550C/fi not_active IP Right Cessation
- 1980-10-15 HU HU802502A patent/HU182213B/hu not_active IP Right Cessation
- 1980-10-15 ZA ZA00806342A patent/ZA806342B/xx unknown
- 1980-10-15 BE BE6/47291A patent/BE885729A/fr not_active IP Right Cessation
- 1980-10-15 BG BG049366A patent/BG34907A3/xx unknown
- 1980-10-15 DK DK437480A patent/DK437480A/da not_active Application Discontinuation
- 1980-10-15 PL PL1980231270A patent/PL135044B1/pl unknown
- 1980-10-16 AR AR282893A patent/AR228041A1/es active
-
1982
- 1982-07-21 AR AR290034A patent/AR228101A1/es active
- 1982-07-28 PH PH27643A patent/PH17759A/en unknown
- 1982-09-29 US US06/426,580 patent/US4486591A/en not_active Expired - Fee Related
-
1983
- 1983-10-11 GB GB838327127A patent/GB8327127D0/en active Pending
-
1984
- 1984-07-24 KR KR1019840004388A patent/KR850000472B1/ko not_active Expired
- 1984-08-06 US US06/638,181 patent/US4542131A/en not_active Expired - Fee Related
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