PT66728B - Process for preparing 2-lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acids - Google Patents

Process for preparing 2-lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acids

Info

Publication number
PT66728B
PT66728B PT66728A PT6672877A PT66728B PT 66728 B PT66728 B PT 66728B PT 66728 A PT66728 A PT 66728A PT 6672877 A PT6672877 A PT 6672877A PT 66728 B PT66728 B PT 66728B
Authority
PT
Portugal
Prior art keywords
cephem
substituted
preparing
lower alkyl
carboxylic acids
Prior art date
Application number
PT66728A
Other languages
English (en)
Portuguese (pt)
Other versions
PT66728A (en
Inventor
Takashi Kamiya
Tsutomu Teraji
Masashi Hashimoto
Osamu Nakaguti
Teruo Oku
Takao Takaya
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26740/76A external-priority patent/GB1580189A/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of PT66728A publication Critical patent/PT66728A/pt
Publication of PT66728B publication Critical patent/PT66728B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PT66728A 1976-06-28 1977-06-27 Process for preparing 2-lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acids PT66728B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26740/76A GB1580189A (en) 1976-06-28 1976-06-28 Cephalosporin derivatives and the preparation thereof
GB26277 1977-01-05

Publications (2)

Publication Number Publication Date
PT66728A PT66728A (en) 1977-07-01
PT66728B true PT66728B (en) 1978-11-22

Family

ID=26235798

Family Applications (1)

Application Number Title Priority Date Filing Date
PT66728A PT66728B (en) 1976-06-28 1977-06-27 Process for preparing 2-lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acids

Country Status (23)

Country Link
US (1) US4225707A (el)
JP (1) JPS5932475B2 (el)
AR (2) AR218254A1 (el)
AT (1) AT353963B (el)
AU (1) AU512804B2 (el)
CA (2) CA1102307A (el)
CH (3) CH634074A5 (el)
CS (1) CS196371B2 (el)
DE (1) DE2728766A1 (el)
DK (1) DK284977A (el)
ES (5) ES460083A1 (el)
FI (1) FI771866A (el)
FR (1) FR2356654A1 (el)
GR (1) GR68939B (el)
HU (1) HU179181B (el)
IE (1) IE45222B1 (el)
NL (1) NL7707150A (el)
NO (1) NO772257L (el)
NZ (1) NZ184493A (el)
OA (1) OA05688A (el)
PT (1) PT66728B (el)
SE (1) SE438337B (el)
SU (1) SU856387A3 (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
EP0009671B1 (en) * 1978-09-12 1984-06-13 Fujisawa Pharmaceutical Co., Ltd. Starting compounds for preparing cephem compounds and processes for their preparation
DE3064106D1 (en) * 1979-06-07 1983-08-18 Yamanouchi Pharma Co Ltd 7-(thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
JPS5946287A (ja) * 1982-07-23 1984-03-15 Meiji Seika Kaisha Ltd 新規１−オキサ−１−デチア−セフアロスポリン誘導体
JPS63107977A (ja) * 1986-05-21 1988-05-12 Takeda Chem Ind Ltd イソオキサゾロン誘導体
JPH09110877A (ja) * 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk セフェム化合物、その製造法及びそれを含有する抗菌剤

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH557381A (de) * 1967-04-15 1974-12-31 Fujisawa Pharmaceutical Co Verfahren zur herstellung von (delta)3-cephemverbindungen.
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3719672A (en) * 1968-12-11 1973-03-06 Ciba Geigy Corp 4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
GB1445979A (en) * 1972-10-25 1976-08-11 Glaxo Lab Ltd Cephalosporin derivatives
AR207341A1 (es) * 1973-03-15 1976-09-30 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2 o 3-cefem-4-carboxilico
JPS5932472B2 (ja) * 1973-03-15 1984-08-09 藤沢薬品工業株式会社 ２−アルキル−７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
JPS5512913B2 (el) * 1974-11-13 1980-04-04
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
JPS5652908B2 (el) * 1974-07-17 1981-12-15
JPS50111093A (el) * 1974-02-20 1975-09-01
JPS5932473B2 (ja) * 1974-02-20 1984-08-09 藤沢薬品工業株式会社 ７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
US3928333A (en) * 1974-05-20 1975-12-23 Lilly Co Eli Process for the preparation of 3 cephalosporin esters
FR2271828B1 (el) * 1974-05-24 1980-02-08 Bristol Myers Co
FR2286138A1 (fr) * 1974-09-27 1976-04-23 Rhone Poulenc Ind Nouveaux acides oxathiino- et dithiino-aminoacetiques et leur preparation
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5246093A (en) * 1975-10-03 1977-04-12 Fujisawa Pharmaceut Co Ltd 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof

Also Published As

Publication number Publication date
ATA449177A (de) 1979-05-15
AT353963B (de) 1979-12-10
ES470756A1 (es) 1979-09-01
HU179181B (en) 1982-09-28
NZ184493A (en) 1980-03-05
GR68939B (el) 1982-03-29
ES460083A1 (es) 1978-10-01
JPS5932475B2 (ja) 1984-08-09
NO772257L (no) 1977-12-29
CS196371B2 (en) 1980-03-31
AR221601A1 (es) 1981-02-27
AU2651977A (en) 1979-01-04
PT66728A (en) 1977-07-01
FR2356654A1 (fr) 1978-01-27
NL7707150A (nl) 1977-12-30
JPS535193A (en) 1978-01-18
CH640538A5 (de) 1984-01-13
CA1117104A (en) 1982-01-26
IE45222L (en) 1977-12-28
FI771866A (el) 1977-12-29
ES470755A1 (es) 1979-09-01
CA1102307A (en) 1981-06-02
DK284977A (da) 1977-12-29
DE2728766A1 (de) 1978-01-05
AR218254A1 (es) 1980-05-30
IE45222B1 (en) 1982-07-14
FR2356654B1 (el) 1981-06-19
ES470754A1 (es) 1979-09-01
AU512804B2 (en) 1980-10-30
CH634074A5 (de) 1983-01-14
US4225707A (en) 1980-09-30
SE438337B (sv) 1985-04-15
ES470757A1 (es) 1979-02-16
SU856387A3 (ru) 1981-08-15
SE7707407L (sv) 1977-12-29
CH640539A5 (de) 1984-01-13
OA05688A (fr) 1981-05-31

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