HU174941B - Sposob poluchenija novykh slozhnykh ehfirov 17al'fa-gidroksy - gestagenov - Google Patents

Sposob poluchenija novykh slozhnykh ehfirov 17al'fa-gidroksy - gestagenov

Info

Publication number
HU174941B
HU174941B HU77LE799A HULE000799A HU174941B HU 174941 B HU174941 B HU 174941B HU 77LE799 A HU77LE799 A HU 77LE799A HU LE000799 A HULE000799 A HU LE000799A HU 174941 B HU174941 B HU 174941B
Authority
HU
Hungary
Prior art keywords
gestageneous
17alpha
hydroxy
esters
preparing new
Prior art date
Application number
HU77LE799A
Other languages
English (en)
Inventor
Hans J Fex
Bertil V Hansen
Krister A Holmberg
Knut B Hoegberg
Imre Koenyves
Original Assignee
Leo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Ab filed Critical Leo Ab
Publication of HU174941B publication Critical patent/HU174941B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU77LE799A 1976-01-22 1977-01-21 Sposob poluchenija novykh slozhnykh ehfirov 17al'fa-gidroksy - gestagenov HU174941B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2419/76A GB1558472A (en) 1976-01-22 1976-01-22 17-esters of 17- hydroxy gestogens

Publications (1)

Publication Number Publication Date
HU174941B true HU174941B (hu) 1980-04-28

Family

ID=9739239

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77LE799A HU174941B (hu) 1976-01-22 1977-01-21 Sposob poluchenija novykh slozhnykh ehfirov 17al'fa-gidroksy - gestagenov

Country Status (18)

Country Link
US (1) US4177269A (hu)
JP (1) JPS52111553A (hu)
AT (1) AT360183B (hu)
AU (1) AU2142677A (hu)
BE (1) BE850668A (hu)
CA (1) CA1087168A (hu)
DE (1) DE2702509A1 (hu)
DK (1) DK25277A (hu)
ES (1) ES455133A1 (hu)
FI (1) FI770191A (hu)
FR (1) FR2338951A1 (hu)
GB (1) GB1558472A (hu)
HU (1) HU174941B (hu)
LU (1) LU76629A1 (hu)
NL (1) NL7700637A (hu)
NO (1) NO770190L (hu)
SE (1) SE7614264L (hu)
SU (1) SU797585A3 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370321A (en) * 1976-09-01 1983-01-25 Mead Johnson And Company Progestational adjuvant therapy
US4260736A (en) * 1978-08-14 1981-04-07 Kureha Kagaku Kogyo Kabushiki Kaisha Steroid hormone-antitumor derivatives
US4261910A (en) * 1978-08-14 1981-04-14 Kureha Kagaku Kogyo Kabushiki Kaisha Process for the preparation of Chlorambucil derivatives
DE3210637A1 (de) * 1982-03-23 1983-09-29 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Steroidester von n-(2-halogenethyl)-n-nitroso-carbamoylaminosaeuren und deren peptiden, sowie verfahren zu deren herstellung
SE8303031D0 (sv) * 1983-05-30 1983-05-30 Leo Ab Improved steroid esters preparation
US4615835A (en) * 1983-11-17 1986-10-07 Stiftung Deutsches Krebsforschungs Zentrum Steroid esters of N-(2-halogenethyl)-N-nitroso-carbamoylamino and acids and peptides therefore, as well as method for preparing them
WO1986000311A1 (en) * 1984-06-27 1986-01-16 Vsesojuzny Onkologichesky Nauchny Tsentr Akademii Derivatives of steroids of androstane series
CH666044A5 (de) * 1984-07-31 1988-06-30 Onkologi N Ct Ak Med V Derivate von 11-desoxy-17 alpha-oxykortikosteron.
JPS61293993A (ja) * 1985-06-21 1986-12-24 Kureha Chem Ind Co Ltd 新規な螢光物質,その製造方法及び薬剤
JPH0621072B2 (ja) * 1986-11-12 1994-03-23 呉羽化学工業株式会社 エストラジオ−ル誘導体よりなる免疫調節剤
WO2024026102A2 (en) * 2022-07-28 2024-02-01 The Johns Hopkins Univeristy Prodrugs for delivery of testosterone to the central nervous system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753360A (en) * 1953-12-12 1956-07-03 Schering A G Fa Esters of 17alpha-hydroxyprogesterone
US4029778A (en) * 1969-01-23 1977-06-14 Aktiebolaget Leo Cortical steroid nitrogen mustard compositions and treatment therewith

Also Published As

Publication number Publication date
DK25277A (da) 1977-07-23
LU76629A1 (hu) 1978-09-13
AT360183B (de) 1980-12-29
CA1087168A (en) 1980-10-07
FI770191A (hu) 1977-07-23
FR2338951B1 (hu) 1979-08-24
SU797585A3 (ru) 1981-01-15
NO770190L (no) 1977-07-25
ATA37877A (de) 1980-05-15
JPS52111553A (en) 1977-09-19
BE850668A (fr) 1977-07-22
GB1558472A (en) 1980-01-03
FR2338951A1 (fr) 1977-08-19
ES455133A1 (es) 1978-05-01
SE7614264L (sv) 1977-07-23
US4177269A (en) 1979-12-04
DE2702509A1 (de) 1977-07-28
AU2142677A (en) 1978-07-27
NL7700637A (nl) 1977-07-26

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