SE438337B - Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar - Google Patents

Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar

Info

Publication number
SE438337B
SE438337B SE7707407A SE7707407A SE438337B SE 438337 B SE438337 B SE 438337B SE 7707407 A SE7707407 A SE 7707407A SE 7707407 A SE7707407 A SE 7707407A SE 438337 B SE438337 B SE 438337B
Authority
SE
Sweden
Prior art keywords
cefem
substituted
methyl
preparing
procedure
Prior art date
Application number
SE7707407A
Other languages
English (en)
Swedish (sv)
Other versions
SE7707407L (sv
Inventor
T Kamiya
T Takaya
T Teraji
M Hashimoto
O Nakaguti
T Oku
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26740/76A external-priority patent/GB1580189A/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of SE7707407L publication Critical patent/SE7707407L/xx
Publication of SE438337B publication Critical patent/SE438337B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
SE7707407A 1976-06-28 1977-06-27 Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar SE438337B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26740/76A GB1580189A (en) 1976-06-28 1976-06-28 Cephalosporin derivatives and the preparation thereof
GB26277 1977-01-05

Publications (2)

Publication Number Publication Date
SE7707407L SE7707407L (sv) 1977-12-29
SE438337B true SE438337B (sv) 1985-04-15

Family

ID=26235798

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7707407A SE438337B (sv) 1976-06-28 1977-06-27 Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar

Country Status (23)

Country Link
US (1) US4225707A (xx)
JP (1) JPS5932475B2 (xx)
AR (2) AR218254A1 (xx)
AT (1) AT353963B (xx)
AU (1) AU512804B2 (xx)
CA (2) CA1117104A (xx)
CH (3) CH634074A5 (xx)
CS (1) CS196371B2 (xx)
DE (1) DE2728766A1 (xx)
DK (1) DK284977A (xx)
ES (5) ES460083A1 (xx)
FI (1) FI771866A (xx)
FR (1) FR2356654A1 (xx)
GR (1) GR68939B (xx)
HU (1) HU179181B (xx)
IE (1) IE45222B1 (xx)
NL (1) NL7707150A (xx)
NO (1) NO772257L (xx)
NZ (1) NZ184493A (xx)
OA (1) OA05688A (xx)
PT (1) PT66728B (xx)
SE (1) SE438337B (xx)
SU (1) SU856387A3 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
DE2967053D1 (en) * 1978-09-12 1984-07-19 Fujisawa Pharmaceutical Co Starting compounds for preparing cephem compounds and processes for their preparation
EP0021688B1 (en) * 1979-06-07 1983-07-13 Yamanouchi Pharmaceutical Co., Ltd. 7-(thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
JPS5946287A (ja) * 1982-07-23 1984-03-15 Meiji Seika Kaisha Ltd 新規１−オキサ−１−デチア−セフアロスポリン誘導体
JPS63107977A (ja) * 1986-05-21 1988-05-12 Takeda Chem Ind Ltd イソオキサゾロン誘導体
JPH09110877A (ja) * 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk セフェム化合物、その製造法及びそれを含有する抗菌剤

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3719672A (en) * 1968-12-11 1973-03-06 Ciba Geigy Corp 4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
GB1445979A (en) * 1972-10-25 1976-08-11 Glaxo Lab Ltd Cephalosporin derivatives
JPS5932472B2 (ja) * 1973-03-15 1984-08-09 藤沢薬品工業株式会社 ２−アルキル−７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
AR207341A1 (es) * 1973-03-15 1976-09-30 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2 o 3-cefem-4-carboxilico
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
JPS5512913B2 (xx) * 1974-11-13 1980-04-04
JPS50111093A (xx) * 1974-02-20 1975-09-01
JPS5652908B2 (xx) * 1974-07-17 1981-12-15
JPS5932473B2 (ja) * 1974-02-20 1984-08-09 藤沢薬品工業株式会社 ７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
US3928333A (en) * 1974-05-20 1975-12-23 Lilly Co Eli Process for the preparation of 3 cephalosporin esters
GB1480027A (en) * 1974-05-24 1977-07-20 Bristol Myers Co Cephalosporin derivatives
FR2286138A1 (fr) * 1974-09-27 1976-04-23 Rhone Poulenc Ind Nouveaux acides oxathiino- et dithiino-aminoacetiques et leur preparation
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5246093A (en) * 1975-10-03 1977-04-12 Fujisawa Pharmaceut Co Ltd 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof

Also Published As

Publication number Publication date
CS196371B2 (en) 1980-03-31
ES470756A1 (es) 1979-09-01
DK284977A (da) 1977-12-29
CH640538A5 (de) 1984-01-13
IE45222L (en) 1977-12-28
ES460083A1 (es) 1978-10-01
NO772257L (no) 1977-12-29
DE2728766A1 (de) 1978-01-05
NZ184493A (en) 1980-03-05
ES470754A1 (es) 1979-09-01
AT353963B (de) 1979-12-10
HU179181B (en) 1982-09-28
CH634074A5 (de) 1983-01-14
ATA449177A (de) 1979-05-15
IE45222B1 (en) 1982-07-14
AR218254A1 (es) 1980-05-30
SU856387A3 (ru) 1981-08-15
AU512804B2 (en) 1980-10-30
ES470757A1 (es) 1979-02-16
US4225707A (en) 1980-09-30
OA05688A (fr) 1981-05-31
JPS5932475B2 (ja) 1984-08-09
FI771866A (xx) 1977-12-29
FR2356654A1 (fr) 1978-01-27
GR68939B (xx) 1982-03-29
CA1102307A (en) 1981-06-02
NL7707150A (nl) 1977-12-30
PT66728A (en) 1977-07-01
JPS535193A (en) 1978-01-18
ES470755A1 (es) 1979-09-01
AR221601A1 (es) 1981-02-27
FR2356654B1 (xx) 1981-06-19
CA1117104A (en) 1982-01-26
AU2651977A (en) 1979-01-04
CH640539A5 (de) 1984-01-13
SE7707407L (sv) 1977-12-29
PT66728B (en) 1978-11-22

Similar Documents

Publication Publication Date Title
DK425579A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK43279A (da) Fremgangsmaade til fremstilling af 2-penem-3-carboxylsyreforbindelser
DK156056C (da) Analogifremgangsmaade til fremstilling af 4-amino-3-quinolin-carboxylsyrederivater
AR230452A1 (es) Procedimiento para preparar compuestos de acidos 7-sustituido-3-cefem-4-carboxilicos
DK363179A (da) Fremgangsmaade til fremstilling af tetrazolylalkoxycarbostyrilderivater
DK457779A (da) Fremgangsmaade til fremstilling af 4-hydroxy-2-pyronderivater
RO76589A (ro) Procedeu pentru prepararea alchilaminelor heterociclice
MX5973E (es) Procedimiento para preparar compuestos cefem
ES490504A0 (es) Procedimiento para preparar nuevos compuestos de tiadiazoli-lo
DK502078A (da) Frefmgangsmaade til fremstilling af cephalosporansyrederivater
DK258078A (da) Fremgangsmaade til fremstilling af 7alfa-methoxy-7beta-(1,3-dithiethan-2-carboxamido) cephalosporansyre-derivater
ES492032A0 (es) Procedimiento para preparar compuestos de cefem
DK396880A (da) Fremgangsmaade til fremstilling af cyclohexancarboxylsyrederivater
DK291979A (da) Fremgangsmaade til opberedning af aluminiumsaltslagger
DK388079A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK455877A (da) Fremgangsmaade til fremstilling af phenyleddikesyrederivater
DK138879A (da) Fremgangsmaade til fremstilling af lysergolderivater
SE438337B (sv) Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar
SE433219B (sv) Forfarande for framstellning av 3-halogenmetylcefalosporinforeningar
DK153489C (da) Analogifremgangsmaade til fremstilling af 7-aminothiazolylacetamidocephalosporansyrederivater
IT1109398B (it) Procedimento per preparare composti di cefalosporina
DK150484C (da) Analogifremgangsmaade til fremstilling af 4-amino-3-thiophencarboxylsyrederivater
FI772629A (fi) Foerfarande foer framstaellning av blodtryckssaenkande 2-(aroylpiperazin-1-yl)-4-amino-6 7-dimetoxikinazoliner
DK394978A (da) Fremgangsmaade til fremstilling af bromerede cephalosporansyrederivater
IT1096154B (it) Procedimento per preparare composti 2-idrossieenzotiazolic