HU179181B - Process for preparing 2-/lower alkyl/-7-substituted-cephem-4-carboxylic acid derivatives - Google Patents

Process for preparing 2-/lower alkyl/-7-substituted-cephem-4-carboxylic acid derivatives

Info

Publication number
HU179181B
HU179181B HU77FU355A HUFU000355A HU179181B HU 179181 B HU179181 B HU 179181B HU 77FU355 A HU77FU355 A HU 77FU355A HU FU000355 A HUFU000355 A HU FU000355A HU 179181 B HU179181 B HU 179181B
Authority
HU
Hungary
Prior art keywords
cephem
substituted
preparing
carboxylic acid
lower alkyl
Prior art date
Application number
HU77FU355A
Other languages
English (en)
Inventor
Takahashi Kamiya
Takeo Takaya
Tautomu Teraji
Masashi Hashimoto
Osamu Nakaguti
Teruo Oku
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26740/76A external-priority patent/GB1580189A/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of HU179181B publication Critical patent/HU179181B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HU77FU355A 1976-06-28 1977-06-28 Process for preparing 2-/lower alkyl/-7-substituted-cephem-4-carboxylic acid derivatives HU179181B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26740/76A GB1580189A (en) 1976-06-28 1976-06-28 Cephalosporin derivatives and the preparation thereof
GB26277 1977-01-05

Publications (1)

Publication Number Publication Date
HU179181B true HU179181B (en) 1982-09-28

Family

ID=26235798

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77FU355A HU179181B (en) 1976-06-28 1977-06-28 Process for preparing 2-/lower alkyl/-7-substituted-cephem-4-carboxylic acid derivatives

Country Status (23)

Country Link
US (1) US4225707A (hu)
JP (1) JPS5932475B2 (hu)
AR (2) AR218254A1 (hu)
AT (1) AT353963B (hu)
AU (1) AU512804B2 (hu)
CA (2) CA1117104A (hu)
CH (3) CH634074A5 (hu)
CS (1) CS196371B2 (hu)
DE (1) DE2728766A1 (hu)
DK (1) DK284977A (hu)
ES (5) ES460083A1 (hu)
FI (1) FI771866A (hu)
FR (1) FR2356654A1 (hu)
GR (1) GR68939B (hu)
HU (1) HU179181B (hu)
IE (1) IE45222B1 (hu)
NL (1) NL7707150A (hu)
NO (1) NO772257L (hu)
NZ (1) NZ184493A (hu)
OA (1) OA05688A (hu)
PT (1) PT66728B (hu)
SE (1) SE438337B (hu)
SU (1) SU856387A3 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
DE2967053D1 (en) * 1978-09-12 1984-07-19 Fujisawa Pharmaceutical Co Starting compounds for preparing cephem compounds and processes for their preparation
EP0021688B1 (en) * 1979-06-07 1983-07-13 Yamanouchi Pharmaceutical Co., Ltd. 7-(thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
JPS5946287A (ja) * 1982-07-23 1984-03-15 Meiji Seika Kaisha Ltd 新規１−オキサ−１−デチア−セフアロスポリン誘導体
JPS63107977A (ja) * 1986-05-21 1988-05-12 Takeda Chem Ind Ltd イソオキサゾロン誘導体
JPH09110877A (ja) * 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk セフェム化合物、その製造法及びそれを含有する抗菌剤

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3719672A (en) * 1968-12-11 1973-03-06 Ciba Geigy Corp 4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
GB1445979A (en) * 1972-10-25 1976-08-11 Glaxo Lab Ltd Cephalosporin derivatives
JPS5932472B2 (ja) * 1973-03-15 1984-08-09 藤沢薬品工業株式会社 ２−アルキル−７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
AR207341A1 (es) * 1973-03-15 1976-09-30 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2 o 3-cefem-4-carboxilico
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
JPS5512913B2 (hu) * 1974-11-13 1980-04-04
JPS50111093A (hu) * 1974-02-20 1975-09-01
JPS5652908B2 (hu) * 1974-07-17 1981-12-15
JPS5932473B2 (ja) * 1974-02-20 1984-08-09 藤沢薬品工業株式会社 ７−アシルアミノ−２（または３）−セフエム−４−カルボン酸類の製造法
US3928333A (en) * 1974-05-20 1975-12-23 Lilly Co Eli Process for the preparation of 3 cephalosporin esters
GB1480027A (en) * 1974-05-24 1977-07-20 Bristol Myers Co Cephalosporin derivatives
FR2286138A1 (fr) * 1974-09-27 1976-04-23 Rhone Poulenc Ind Nouveaux acides oxathiino- et dithiino-aminoacetiques et leur preparation
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5246093A (en) * 1975-10-03 1977-04-12 Fujisawa Pharmaceut Co Ltd 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof

Also Published As

Publication number Publication date
CS196371B2 (en) 1980-03-31
ES470756A1 (es) 1979-09-01
DK284977A (da) 1977-12-29
CH640538A5 (de) 1984-01-13
IE45222L (en) 1977-12-28
ES460083A1 (es) 1978-10-01
NO772257L (no) 1977-12-29
DE2728766A1 (de) 1978-01-05
NZ184493A (en) 1980-03-05
ES470754A1 (es) 1979-09-01
AT353963B (de) 1979-12-10
CH634074A5 (de) 1983-01-14
ATA449177A (de) 1979-05-15
IE45222B1 (en) 1982-07-14
AR218254A1 (es) 1980-05-30
SU856387A3 (ru) 1981-08-15
AU512804B2 (en) 1980-10-30
ES470757A1 (es) 1979-02-16
US4225707A (en) 1980-09-30
OA05688A (fr) 1981-05-31
JPS5932475B2 (ja) 1984-08-09
FI771866A (hu) 1977-12-29
FR2356654A1 (fr) 1978-01-27
SE438337B (sv) 1985-04-15
GR68939B (hu) 1982-03-29
CA1102307A (en) 1981-06-02
NL7707150A (nl) 1977-12-30
PT66728A (en) 1977-07-01
JPS535193A (en) 1978-01-18
ES470755A1 (es) 1979-09-01
AR221601A1 (es) 1981-02-27
FR2356654B1 (hu) 1981-06-19
CA1117104A (en) 1982-01-26
AU2651977A (en) 1979-01-04
CH640539A5 (de) 1984-01-13
SE7707407L (sv) 1977-12-29
PT66728B (en) 1978-11-22

Similar Documents

Publication Publication Date Title
YU42807B (en) Process for preparing phthalazine-4-yl-acetic acid derivatives
PT66854A (en) Process for preparing new hydroxyaminohydrocarbonphosphonic acid derivatives
HU172711B (hu) Sposob poluchenija proizvodnykh piperidil-indola
PT66713B (en) Process for preparing 4-hydroxyphenylalkanolamine derivatives
HU178040B (en) Process for preparing 8-aza-prostaglandin derivatives
HU179181B (en) Process for preparing 2-/lower alkyl/-7-substituted-cephem-4-carboxylic acid derivatives
HU179484B (en) Process for preparing 3-amino-thiophene-4-carboxylic acid derivatives
HU173606B (hu) Sposob poluchenija proizvodnykh benzo-sul'fo-karbamida
HU178806B (en) Process for preparing benzyl-cyano-acetal derivatives
HU174982B (hu) Sposob poluchenija proizvodnykh 17al'fa-gidroksi-pregnan-20-ona
PT67783A (en) Process for preparing oleanoic acid derivatives
HU179449B (en) Process for preparing substituted 2-vinyl-chromon derivatives
HU179596B (en) Process for preparing 7-acetamido-3-methyl-cef-3-eme-4-carboxylic acid derivatives
JPS52148100A (en) Process for preparing novel liphamycine derivatives
JPS5323948A (en) Novel process for preparing streptamine derivatives
YU123177A (en) Process for obtaining indolyl-acetic acid derivatives
HU174071B (hu) Sposob poluchenija proizvodnykh oksazolino-azetidinil-pentenovoj kisloty
HU177936B (en) Process for preparing 1-dialkylamino-2-alkin-4-ol derivatives
HU176954B (hu) Sposob poluchenija proizvodnykh cis-geksagidro-dibenzopiranona
ZA777627B (en) Process for preparing pyrrolo-benzoic acid derivatives
YU32578A (en) Process for preparing 3-carboyphenyl-acetic acid derivatives
HU183632B (en) Process for preparing 4-thioxy-2-azetidinone derivatives
YU70177A (en) Process for preparing sandwicin derivatives
CS193538B2 (en) Process for preparing derivatives n-aminoalkyl-n-phenyl--2-aminoindane
PT67456B (en) Process for preparing omega-aryl-13-prostynoic acid derivatives