PT3954225T - Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5' - Google Patents

Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5'

Info

Publication number
PT3954225T
PT3954225T PT211731427T PT21173142T PT3954225T PT 3954225 T PT3954225 T PT 3954225T PT 211731427 T PT211731427 T PT 211731427T PT 21173142 T PT21173142 T PT 21173142T PT 3954225 T PT3954225 T PT 3954225T
Authority
PT
Portugal
Prior art keywords
synthesizing
compositions
methods
capped rnas
rnas
Prior art date
Application number
PT211731427T
Other languages
English (en)
Original Assignee
Trilink Biotechnologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58387109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3954225(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trilink Biotechnologies Llc filed Critical Trilink Biotechnologies Llc
Publication of PT3954225T publication Critical patent/PT3954225T/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13Nucleic acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/712Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/353Nature of the modification linked to the nucleic acid via an atom other than carbon
    • C12N2310/3533Halogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
PT211731427T 2015-09-21 2016-09-20 Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5' PT3954225T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562221248P 2015-09-21 2015-09-21

Publications (1)

Publication Number Publication Date
PT3954225T true PT3954225T (pt) 2024-01-02

Family

ID=58387109

Family Applications (5)

Application Number Title Priority Date Filing Date
PT211732789T PT3906789T (pt) 2015-09-21 2016-09-20 Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5'
PT221753775T PT4104687T (pt) 2015-09-21 2016-09-20 Composições e métodos para a sintetização de arn capeados em 5'
PT168494235T PT3352584T (pt) 2015-09-21 2016-09-20 Composições e métodos para a sintetização de arn capeados em 5¿
PT211731427T PT3954225T (pt) 2015-09-21 2016-09-20 Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5'
PT221904261T PT4140491T (pt) 2015-09-21 2016-09-20 Métolo para a sintetização de arn capeados em 5

Family Applications Before (3)

Application Number Title Priority Date Filing Date
PT211732789T PT3906789T (pt) 2015-09-21 2016-09-20 Iniciadores de oligonucleótidos de iniciação para a sintetização de arn capeados em 5'
PT221753775T PT4104687T (pt) 2015-09-21 2016-09-20 Composições e métodos para a sintetização de arn capeados em 5'
PT168494235T PT3352584T (pt) 2015-09-21 2016-09-20 Composições e métodos para a sintetização de arn capeados em 5¿

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT221904261T PT4140491T (pt) 2015-09-21 2016-09-20 Métolo para a sintetização de arn capeados em 5

Country Status (20)

Country Link
US (7) US10913768B2 (pt)
EP (7) EP3954224A1 (pt)
JP (3) JP6814997B2 (pt)
KR (2) KR20230026535A (pt)
CN (5) CN116590285A (pt)
AU (4) AU2016328645C1 (pt)
CA (2) CA2999274C (pt)
CY (1) CY1124306T1 (pt)
DK (5) DK4140491T3 (pt)
ES (2) ES2879686T3 (pt)
FI (4) FI3954225T3 (pt)
HK (1) HK1255236A1 (pt)
HR (1) HRP20211091T1 (pt)
HU (2) HUE055458T2 (pt)
LT (5) LT4140491T (pt)
PL (2) PL3352584T3 (pt)
PT (5) PT3906789T (pt)
RS (1) RS62129B1 (pt)
SI (5) SI4140491T1 (pt)
WO (1) WO2017053297A1 (pt)

Families Citing this family (135)

* Cited by examiner, † Cited by third party
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