PT2934145T - Inibidores de histona demetilase - Google Patents

Inibidores de histona demetilase

Info

Publication number
PT2934145T
PT2934145T PT138664651T PT13866465T PT2934145T PT 2934145 T PT2934145 T PT 2934145T PT 138664651 T PT138664651 T PT 138664651T PT 13866465 T PT13866465 T PT 13866465T PT 2934145 T PT2934145 T PT 2934145T
Authority
PT
Portugal
Prior art keywords
demetilase
histone
inhibitors
histone inhibitors
inhibitors demetilase
Prior art date
Application number
PT138664651T
Other languages
English (en)
Portuguese (pt)
Inventor
Alan Stafford Jeffrey
Marvin Veal James
Brennan Wallace Michael
Kanouni Toufike
Original Assignee
Celgene Quanticel Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Quanticel Res Inc filed Critical Celgene Quanticel Res Inc
Publication of PT2934145T publication Critical patent/PT2934145T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PT138664651T 2012-12-19 2013-12-19 Inibidores de histona demetilase PT2934145T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261739521P 2012-12-19 2012-12-19
US201361792930P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
PT2934145T true PT2934145T (pt) 2018-02-13

Family

ID=50931614

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138664651T PT2934145T (pt) 2012-12-19 2013-12-19 Inibidores de histona demetilase

Country Status (17)

Country Link
US (4) US9617242B2 (cg-RX-API-DMAC10.html)
EP (1) EP2934145B1 (cg-RX-API-DMAC10.html)
JP (1) JP6256772B2 (cg-RX-API-DMAC10.html)
AU (1) AU2013361255B2 (cg-RX-API-DMAC10.html)
CA (1) CA2895355A1 (cg-RX-API-DMAC10.html)
CY (1) CY1119901T1 (cg-RX-API-DMAC10.html)
DK (1) DK2934145T3 (cg-RX-API-DMAC10.html)
ES (1) ES2658597T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20180067T1 (cg-RX-API-DMAC10.html)
HU (1) HUE037312T2 (cg-RX-API-DMAC10.html)
LT (1) LT2934145T (cg-RX-API-DMAC10.html)
PL (1) PL2934145T3 (cg-RX-API-DMAC10.html)
PT (1) PT2934145T (cg-RX-API-DMAC10.html)
RS (1) RS56821B1 (cg-RX-API-DMAC10.html)
SI (1) SI2934145T1 (cg-RX-API-DMAC10.html)
SM (1) SMT201800070T1 (cg-RX-API-DMAC10.html)
WO (1) WO2014100463A1 (cg-RX-API-DMAC10.html)

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Also Published As

Publication number Publication date
EP2934145A4 (en) 2016-06-29
US8969343B2 (en) 2015-03-03
PL2934145T3 (pl) 2018-04-30
SI2934145T1 (en) 2018-03-30
ES2658597T3 (es) 2018-03-12
SMT201800070T1 (it) 2018-03-08
CA2895355A1 (en) 2014-06-26
RS56821B1 (sr) 2018-04-30
HRP20180067T1 (hr) 2018-02-23
US10040779B2 (en) 2018-08-07
CY1119901T1 (el) 2018-06-27
US20180305336A1 (en) 2018-10-25
WO2014100463A1 (en) 2014-06-26
US20170174656A1 (en) 2017-06-22
US10336727B2 (en) 2019-07-02
DK2934145T3 (en) 2018-02-05
US20140171432A1 (en) 2014-06-19
US20160060247A1 (en) 2016-03-03
AU2013361255A1 (en) 2015-07-09
JP2016503799A (ja) 2016-02-08
JP6256772B2 (ja) 2018-01-10
LT2934145T (lt) 2018-02-26
US9617242B2 (en) 2017-04-11
HUE037312T2 (hu) 2018-08-28
EP2934145B1 (en) 2017-11-15
AU2013361255B2 (en) 2017-01-05
EP2934145A1 (en) 2015-10-28

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