PT2797601T - Composições farmacêuticas para reduzir complicações de esteroide ocular - Google Patents

Composições farmacêuticas para reduzir complicações de esteroide ocular

Info

Publication number
PT2797601T
PT2797601T PT137470217T PT13747021T PT2797601T PT 2797601 T PT2797601 T PT 2797601T PT 137470217 T PT137470217 T PT 137470217T PT 13747021 T PT13747021 T PT 13747021T PT 2797601 T PT2797601 T PT 2797601T
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
reduce complications
ocular steroid
steroid
ocular
Prior art date
Application number
PT137470217T
Other languages
English (en)
Portuguese (pt)
Inventor
Hong Keelung
S S Guo Luke
Tseng Yun-Long
Shih Sheue-Fang
Chang Po-Chun
Tsai Chih-Chiang
Lin Hong-Hui
Original Assignee
Taiwan Liposome Co Ltd
Tlc Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiwan Liposome Co Ltd, Tlc Biopharmaceuticals Inc filed Critical Taiwan Liposome Co Ltd
Publication of PT2797601T publication Critical patent/PT2797601T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT137470217T 2012-02-10 2013-02-08 Composições farmacêuticas para reduzir complicações de esteroide ocular PT2797601T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261597189P 2012-02-10 2012-02-10

Publications (1)

Publication Number Publication Date
PT2797601T true PT2797601T (pt) 2018-06-27

Family

ID=48948063

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137470217T PT2797601T (pt) 2012-02-10 2013-02-08 Composições farmacêuticas para reduzir complicações de esteroide ocular

Country Status (18)

Country Link
US (2) US10058616B2 (enExample)
EP (1) EP2797601B1 (enExample)
JP (1) JP6231995B2 (enExample)
KR (1) KR102060210B1 (enExample)
CN (2) CN104125830B (enExample)
AU (1) AU2013216861B2 (enExample)
BR (1) BR112014018393B1 (enExample)
CA (1) CA2862055C (enExample)
CY (1) CY1120323T1 (enExample)
DK (1) DK2797601T3 (enExample)
ES (1) ES2673330T3 (enExample)
IN (1) IN2014MN01571A (enExample)
NZ (1) NZ628124A (enExample)
PT (1) PT2797601T (enExample)
RU (1) RU2660585C2 (enExample)
TR (1) TR201808592T4 (enExample)
TW (1) TWI620578B (enExample)
WO (1) WO2013119988A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3445335A4 (en) * 2016-04-19 2020-03-04 Nanyang Technological University FORMULATIONS FORMING A SUB-CONJUNCTIVAL DEPOSIT FOR THE ADMINISTRATION OF MEDICATION AT THE EYE LEVEL
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease
KR102712798B1 (ko) * 2017-11-21 2024-10-04 씨에스 파마슈티컬스 리미티드 안구주위 분비선 또는 안구 표면에서의 이상 염증을 치료하기 위한 조성물 및 사용 방법
US11759472B2 (en) 2017-11-21 2023-09-19 Cs Pharmaceuticals Limited Compositions and methods of use for treating aberrant inflammation in peri-ocular secretory glands or at the ocular surface
EP3820479A1 (en) * 2018-07-09 2021-05-19 Taiwan Liposome Co., Ltd. Methods to reduce complications of intra-articular steroid
BR112021004880A2 (pt) 2018-09-16 2021-06-01 Tlc Biopharmaceuticals, Inc. composições farmacêuticas adequadas para entrega articular e uso das mesmas no tratamento de dor nas articulações
KR20210141448A (ko) 2018-12-27 2021-11-23 서피스 아프샐믹스 인코포레이티드 안구 표면 질환을 치료하기 위한 안과용 약학 조성물 및 방법
RU2716429C1 (ru) * 2019-05-29 2020-03-11 федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ лечения рецидивирующей эрозии роговицы различного генеза
CN111415822A (zh) * 2020-03-05 2020-07-14 沈阳农业大学 一种洋葱碳/二氧化锰阵列电极及其制备方法和应用
US12440510B2 (en) 2021-05-10 2025-10-14 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain
CN117979951A (zh) 2021-05-10 2024-05-03 瑟菲斯眼科股份有限公司 一种用于缓解眼部疼痛的硫酸软骨素的用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
SE9100342D0 (sv) 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
IL103907A0 (en) * 1992-11-27 1993-04-04 Pharmos Corp Ophthalmic compositions
CN100367932C (zh) * 2002-11-26 2008-02-13 吉里德科学公司 借助梯度的脂质体中药物装填的方法
CN100374165C (zh) 2003-02-04 2008-03-12 伯拉考国际股份公司 超声造影剂及其制备方法
EP1768657B1 (en) * 2004-06-23 2008-08-13 Sirion Therapeutics, Inc. Methods and compositions for treating ophthalmic conditions with retinyl derivates
US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
US20070280902A1 (en) * 2006-06-01 2007-12-06 Laura Rabinovich-Guilatt Method for treating eye disease or conditions affecting the posterior segment of the eye
KR20090029814A (ko) * 2006-06-22 2009-03-23 시리온 테라퓨틱스, 인크. 메갈린 활성의 조절을 통한 안질환의 치료 방법 및 조성물
US20080118500A1 (en) * 2006-11-16 2008-05-22 Taiwan Liposome Company Sustained releasing composition via local injection for treating eye diseases
US9114070B2 (en) 2008-02-29 2015-08-25 Nagoya Industrial Science Research Institute Liposome for delivery to posterior segment of eye and pharmaceutical composition for disease in posterior segment of eye
CN101502485A (zh) * 2009-03-20 2009-08-12 中国药科大学 地塞米松眼用纳米立方液晶制剂及其制备方法
CN101926769A (zh) * 2009-06-24 2010-12-29 天津金耀集团有限公司 地塞米松磷酸钠脂质体注射液
US8956600B2 (en) * 2009-08-10 2015-02-17 Taiwan Liposome Co. Ltd. Ophthalmic drug delivery system containing phospholipid and cholesterol
JP5686886B2 (ja) 2010-03-19 2015-03-18 マサチューセッツ インスチテュート オブ テクノロジーMassachusetts Institute Of Technology 脂質小胞組成物及び使用方法
US20130217657A1 (en) * 2011-12-21 2013-08-22 Insite Vision Incorporated Combination anti-inflammatory ophthalmic compositions

Also Published As

Publication number Publication date
EP2797601A1 (en) 2014-11-05
BR112014018393B1 (pt) 2020-09-15
US10058616B2 (en) 2018-08-28
CN104125830B (zh) 2018-01-16
TWI620578B (zh) 2018-04-11
AU2013216861B2 (en) 2017-05-18
US10350294B2 (en) 2019-07-16
BR112014018393A8 (pt) 2017-07-11
CY1120323T1 (el) 2019-07-10
CN107260679B (zh) 2020-07-31
KR102060210B1 (ko) 2019-12-27
BR112014018393A2 (enExample) 2017-06-20
TW201338806A (zh) 2013-10-01
JP2015506983A (ja) 2015-03-05
US20180193461A1 (en) 2018-07-12
AU2013216861A1 (en) 2014-08-07
RU2014132553A (ru) 2016-02-27
CA2862055A1 (en) 2013-08-15
CA2862055C (en) 2020-03-10
JP6231995B2 (ja) 2017-11-15
KR20150008844A (ko) 2015-01-23
EP2797601B1 (en) 2018-03-21
ES2673330T3 (es) 2018-06-21
DK2797601T3 (en) 2018-06-14
CN107260679A (zh) 2017-10-20
IN2014MN01571A (enExample) 2015-05-15
TR201808592T4 (tr) 2018-07-23
RU2660585C2 (ru) 2018-07-06
US20150011520A1 (en) 2015-01-08
NZ628124A (en) 2016-06-24
WO2013119988A1 (en) 2013-08-15
CN104125830A (zh) 2014-10-29
EP2797601A4 (en) 2015-06-03
HK1201723A1 (en) 2015-09-11

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