SG11201400668SA - Wnt compositions and therapeutic uses of such compositions - Google Patents

Wnt compositions and therapeutic uses of such compositions

Info

Publication number
SG11201400668SA
SG11201400668SA SG11201400668SA SG11201400668SA SG11201400668SA SG 11201400668S A SG11201400668S A SG 11201400668SA SG 11201400668S A SG11201400668S A SG 11201400668SA SG 11201400668S A SG11201400668S A SG 11201400668SA SG 11201400668S A SG11201400668S A SG 11201400668SA
Authority
SG
Singapore
Prior art keywords
compositions
wnt
therapeutic uses
therapeutic
wnt compositions
Prior art date
Application number
SG11201400668SA
Inventor
Tom Tong Lee
Michael J Fitch
Kevin Lai
Monica Bennett
Peter Flynn
Original Assignee
Fate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47883976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201400668S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fate Therapeutics Inc filed Critical Fate Therapeutics Inc
Publication of SG11201400668SA publication Critical patent/SG11201400668SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201400668SA 2011-09-16 2012-09-14 Wnt compositions and therapeutic uses of such compositions SG11201400668SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161535913P 2011-09-16 2011-09-16
PCT/US2012/055336 WO2013040309A2 (en) 2011-09-16 2012-09-14 Wnt compositions and therapeutic uses of such compositions

Publications (1)

Publication Number Publication Date
SG11201400668SA true SG11201400668SA (en) 2014-04-28

Family

ID=47883976

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400668SA SG11201400668SA (en) 2011-09-16 2012-09-14 Wnt compositions and therapeutic uses of such compositions

Country Status (10)

Country Link
US (1) US9873722B2 (en)
EP (1) EP2748190A4 (en)
JP (1) JP2014527818A (en)
KR (1) KR20140062139A (en)
CN (1) CN103998462A (en)
AU (2) AU2012308476B2 (en)
BR (1) BR112014006321A2 (en)
CA (1) CA2848841A1 (en)
SG (1) SG11201400668SA (en)
WO (1) WO2013040309A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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CA3065736A1 (en) 2009-04-27 2010-11-04 Ottawa Hospital Research Institute Compositions and methods for modulating stem cells and uses thereof
EP2663576B1 (en) * 2011-01-11 2017-11-01 Fate Therapeutics, Inc. Novel wnt compositions and therapeutic uses of such compositions
SG11201400668SA (en) 2011-09-16 2014-04-28 Fate Therapeutics Inc Wnt compositions and therapeutic uses of such compositions
ES2690305T3 (en) 2011-09-16 2018-11-20 Ottawa Hospital Research Institute Wnt7a compositions and methods of use thereof
WO2013149337A1 (en) 2012-04-02 2013-10-10 Hydrogenics Corporation Fuel cell start up method
EP3052121B1 (en) 2013-10-02 2023-02-22 The Board of Trustees of the Leland Stanford Junior University Wnt compositions and methods for purification
WO2015148923A1 (en) * 2014-03-28 2015-10-01 Ottawa Hospital Research Institute Wnt induced motility and enhanced engraftment of cells
EP2975047A1 (en) 2014-07-18 2016-01-20 Université de Lausanne Wnt7a polypeptides and their use
EP3197465A4 (en) * 2014-09-22 2018-04-25 Rush University Medical Center Compositions and methods for treating a viral infection
US10550364B2 (en) 2014-12-24 2020-02-04 Osaka University Method for producing Wnt protein and method for storing Wnt protein
CA2988306A1 (en) 2015-06-05 2016-12-08 Vertex Pharmaceuticals Incorporated Triazoles for the treatment of demyelinating diseases
US20180360025A1 (en) * 2015-07-22 2018-12-20 Ramot At Tel-Aviv University Ltd. Article of manufacture and methods for increasing survival of red blood cells
WO2017132494A1 (en) * 2016-01-28 2017-08-03 The Board Of Trustees Of The Leland Stanford Junior University Wnt compositions and methods for serum-free synthesis
WO2018106643A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Heterocyclic azoles for the treatment of demyelinating diseases
WO2018106641A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Pyrazoles for the treatment of demyelinating diseases
WO2018106646A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Aminotriazoles for the treatment of demyelinating diseases
CN108623692B (en) * 2017-03-20 2020-11-17 徐寒梅 Fusion protein, preparation method and application thereof
CA3071638A1 (en) * 2017-08-01 2019-02-07 Ankasa Regenerative Therapeutics, Inc. Wnt compositions and methods of process from serum-free culturing conditions
AU2018368440B2 (en) * 2017-11-16 2022-03-03 Aivita Biomedical, Inc. Use of cell membrane-bound signaling factors
US11773171B2 (en) * 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
EP3728323A4 (en) 2017-12-19 2022-01-26 Surrozen Operating, Inc. Anti-frizzled antibodies and methods of use
CN113282524B (en) * 2021-05-08 2022-08-16 重庆大学 Configuration method and device of cache fragments and storage medium

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US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
AU660629B2 (en) 1990-10-01 1995-07-06 University Of Connecticut, The Targeting viruses and cells for selective internalization by cells
CA2103371C (en) 1991-06-05 2003-09-16 George Y. Wu Targeted delivery of genes encoding secretory proteins
WO1993014188A1 (en) 1992-01-17 1993-07-22 The Regents Of The University Of Michigan Targeted virus
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US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
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WO2010014948A1 (en) 2008-08-01 2010-02-04 The University Of Utah Research Foundation Methods of treatment using wnt inhibitors
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SG11201400668SA (en) 2011-09-16 2014-04-28 Fate Therapeutics Inc Wnt compositions and therapeutic uses of such compositions
ES2690305T3 (en) 2011-09-16 2018-11-20 Ottawa Hospital Research Institute Wnt7a compositions and methods of use thereof

Also Published As

Publication number Publication date
AU2016201547A1 (en) 2016-03-31
CA2848841A1 (en) 2013-03-21
CN103998462A (en) 2014-08-20
EP2748190A4 (en) 2015-01-21
EP2748190A2 (en) 2014-07-02
US9873722B2 (en) 2018-01-23
KR20140062139A (en) 2014-05-22
WO2013040309A2 (en) 2013-03-21
BR112014006321A2 (en) 2017-04-11
JP2014527818A (en) 2014-10-23
AU2012308476A1 (en) 2013-04-18
WO2013040309A3 (en) 2013-05-10
US20150099708A1 (en) 2015-04-09
AU2012308476B2 (en) 2016-04-14

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