PT2500017T - Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade - Google Patents
Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idadeInfo
- Publication number
- PT2500017T PT2500017T PT121605992T PT12160599T PT2500017T PT 2500017 T PT2500017 T PT 2500017T PT 121605992 T PT121605992 T PT 121605992T PT 12160599 T PT12160599 T PT 12160599T PT 2500017 T PT2500017 T PT 2500017T
- Authority
- PT
- Portugal
- Prior art keywords
- age
- treatment
- associated memory
- memory impairment
- ketogenic compounds
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74414006P | 2006-04-03 | 2006-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2500017T true PT2500017T (pt) | 2017-11-14 |
Family
ID=38564302
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT121605992T PT2500017T (pt) | 2006-04-03 | 2007-04-03 | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade |
PT07797196T PT2001293T (pt) | 2006-04-03 | 2007-04-03 | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT07797196T PT2001293T (pt) | 2006-04-03 | 2007-04-03 | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade |
Country Status (11)
Country | Link |
---|---|
US (3) | US8124589B2 (pt) |
EP (2) | EP2500017B1 (pt) |
JP (4) | JP2009532496A (pt) |
KR (2) | KR101634083B1 (pt) |
DK (2) | DK2500017T3 (pt) |
ES (2) | ES2645816T3 (pt) |
HU (2) | HUE040002T2 (pt) |
LT (2) | LT2500017T (pt) |
PT (2) | PT2500017T (pt) |
SI (1) | SI2001293T1 (pt) |
WO (1) | WO2007115282A2 (pt) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
WO2001082928A1 (en) | 2000-05-01 | 2001-11-08 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
ES2670413T3 (es) | 2003-06-03 | 2018-05-30 | The United States Government As Represented By The Department Of Health And Human Services | Suplementos nutricionales y composiciones terapéuticas que comprenden derivados de (R)-3-hidroxibutirato |
US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
EP1915144A4 (en) * | 2005-06-20 | 2009-08-19 | Accera Inc | METHOD FOR REDUCING OXIDATIVE DAMAGE AND IMPROVING MITOCHONDRIA EFFICIENCY |
HUE037129T2 (hu) * | 2005-12-15 | 2018-08-28 | Nestec Sa | Kompozíciók és eljárások agyi funkció megõrzésére |
ES2645816T3 (es) | 2006-04-03 | 2017-12-07 | Accera, Inc. | Uso de compuestos cetogénicos para el tratamiento de la alteración de la memoria asociada a la edad |
EP1929995A1 (en) | 2006-12-04 | 2008-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anaplerotic therapy of Huntington disease and other polyglutamine diseases |
CA2685380A1 (en) * | 2007-05-14 | 2008-11-20 | Neuera Pharmaceuticals, Inc. | Inhibitors of acetyl-coa carboxylase for treatment of neuronal hypometabolism |
PT2650382E (pt) | 2007-07-31 | 2016-01-14 | Accera Inc | Utilização de testagem genómica e compostos cetogénicos para o tratamento de função cognitiva reduzida |
ES2773928T5 (es) * | 2008-01-04 | 2023-06-28 | Nestle Sa | Composiciones que comprenden ácidos grasos insaturados y compuestos de liberación de óxido nítrico y uso de las mismas para la intensificación de las funciones cognitivas y relacionadas |
CN106038532B (zh) | 2008-01-04 | 2019-05-14 | 牛津大学科技创新有限公司 | 用作降低血脂药剂的酮体和酮体酯 |
US8105809B2 (en) * | 2008-07-03 | 2012-01-31 | Accera, Inc. | Enzymatic synthesis of acetoacetate esters and derivatives |
KR101734152B1 (ko) | 2008-07-03 | 2017-05-11 | 액세라인크 | 신경계 장애의 치료를 위한 아세토아세테이트의 모노글리세리드 및 유도체 |
SG195572A1 (en) * | 2008-07-18 | 2013-12-30 | Dart Neuroscience Cayman Ltd | Methods and systems for evaluating memory agents |
US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
JP5059947B2 (ja) | 2008-11-06 | 2012-10-31 | 日清オイリオグループ株式会社 | 濃厚流動食 |
ES2640777T3 (es) | 2009-12-30 | 2017-11-06 | Baylor Research Institute | Terapia anaplerótica para la enfermedad de Alzheimer |
GB201002983D0 (en) * | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
BR112012024214A2 (pt) * | 2010-03-24 | 2019-09-24 | Nestec Sa | método para melhorar a palatabilidade de composições comestíveis. |
WO2014071389A1 (en) | 2012-11-05 | 2014-05-08 | Veech Richard L | Ketone bodies to protect tissues from damage by ionizing radiation |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
CA2894456C (en) | 2012-12-13 | 2022-06-28 | Baylor Research Institute | Triheptanoin for the treatment of glucose transporter 1 deficiency |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
SG11201507685UA (en) | 2013-03-14 | 2015-10-29 | Isis Innovation | Process for producing (r)-3-hydroxybutyl (r)-3-hydroxybutyrate |
BR112015024186B1 (pt) | 2013-03-19 | 2023-05-09 | University Of South Florida | Composições e métodos para produção de cetose de elevação e manutenção |
US9833430B2 (en) | 2013-11-14 | 2017-12-05 | The University Of Queensland | Neurodegenerative disorders and methods of treatment and diagnosis thereof |
US20170202239A1 (en) * | 2014-07-17 | 2017-07-20 | The Nisshin Oillio Group, Ltd. | Baked confectionery that substantially includes no flour |
CA2955915A1 (en) * | 2014-07-23 | 2016-01-28 | The Food Science Institute Foundation | Agent for improving brain function and agent for preventing or treating cognitive impairment |
ES2761826T3 (es) | 2014-12-08 | 2020-05-21 | Nestle Sa | Composiciones que contienen triglicéridos de cadena media para su uso en el tratamiento de la epilepsia |
US10668041B2 (en) | 2014-12-08 | 2020-06-02 | Societe Des Produits Nestle Sa | Compositions and methods comprising medium chain triglycerides for treatment of epilepsy |
JP6446265B2 (ja) * | 2014-12-26 | 2018-12-26 | 花王株式会社 | 固形状組成物 |
EP3419959A4 (en) * | 2016-02-23 | 2019-10-23 | Carnot, LLC | COMBINATION THERAPY |
US10736861B2 (en) | 2016-03-11 | 2020-08-11 | Axcess Global Sciences, Llc | Mixed salt compositions for producing elevated and sustained ketosis |
US10245242B1 (en) | 2017-11-22 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US11185518B2 (en) | 2017-12-19 | 2021-11-30 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer |
US10245243B1 (en) | 2017-12-19 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US10596129B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10973792B2 (en) | 2019-02-13 | 2021-04-13 | Axcess Global Sciences, Llc | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use |
US10292952B2 (en) | 2016-03-11 | 2019-05-21 | Axcess Global Sciences, Llc | Mixed salt compositions for maintaining or restoring electrolyte balance while producing elevated and sustained ketosis |
US10596130B2 (en) | 2017-12-19 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US10596131B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US11241403B2 (en) | 2016-03-11 | 2022-02-08 | Axcess Global Sciences, Llc | Beta-hydroxybutyrate mixed salt compositions and methods of use |
US10973786B2 (en) | 2016-03-11 | 2021-04-13 | Axcess Global Sciences, Llc | R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions |
US11103470B2 (en) | 2017-11-22 | 2021-08-31 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
JP6923940B2 (ja) * | 2016-04-15 | 2021-08-25 | 慶裕 広川 | 認知機能改善剤 |
JP6935994B2 (ja) | 2016-08-19 | 2021-09-15 | 株式会社明治 | ケトン体生成促進用組成物 |
US10945975B2 (en) * | 2016-10-24 | 2021-03-16 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
US20180177753A1 (en) | 2016-12-23 | 2018-06-28 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for migraine symptom management |
US9925164B1 (en) | 2017-01-12 | 2018-03-27 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for traumatic brain injury |
US10376528B2 (en) | 2017-03-10 | 2019-08-13 | Tecton Group, Llc | Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor |
JP6895144B2 (ja) * | 2017-04-05 | 2021-06-30 | 北海道公立大学法人 札幌医科大学 | 診断支援システム、診断支援システムの作動方法、及びプログラム |
US10957290B2 (en) * | 2017-08-31 | 2021-03-23 | Spotify Ab | Lyrics analyzer |
US11202769B2 (en) | 2017-11-22 | 2021-12-21 | Axcess Global Sciences, Llc | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function |
US10925843B2 (en) | 2018-04-18 | 2021-02-23 | Axcess Global Sciences, Llc | Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate |
US12090129B2 (en) | 2017-11-22 | 2024-09-17 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US11944598B2 (en) | 2017-12-19 | 2024-04-02 | Axcess Global Sciences, Llc | Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer |
US11129802B2 (en) | 2018-08-27 | 2021-09-28 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
US11241401B2 (en) | 2020-02-06 | 2022-02-08 | Axcess Global Sciences, Llc | Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions |
US10980772B2 (en) | 2018-08-27 | 2021-04-20 | Axcess Global Sciences, Llc | Compositions and methods for delivering tetrahydrocannabinol and ketone bodies |
US11806324B2 (en) | 2018-04-18 | 2023-11-07 | Axcess Global Sciences, Llc | Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies |
US11419836B2 (en) | 2019-02-13 | 2022-08-23 | Axcess Global Sciences, Llc | Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions |
US10512615B1 (en) | 2018-08-27 | 2019-12-24 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
JP7410055B2 (ja) * | 2018-06-21 | 2024-01-09 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | ニコチンアミドアデニンジヌクレオチド(nad+)前駆体及び少なくとも1種のケトン又はケトン前駆体を使用する組成物及び方法 |
CA3129751A1 (en) * | 2019-02-11 | 2020-08-20 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with s-enantiomer |
CN113747890A (zh) * | 2019-02-11 | 2021-12-03 | 阿克塞斯全球科学有限责任公司 | 外消旋β-羟基丁酸盐混合盐-酸组合物和使用方法 |
SG11202109268XA (en) * | 2019-03-04 | 2021-09-29 | Cerecin Inc | Medium chain triglyceride formulations with improved bioavailiblity and methods related thereto |
JP7458620B2 (ja) * | 2019-06-21 | 2024-04-01 | 株式会社大塚製薬工場 | 栄養組成物 |
US11033553B2 (en) | 2019-06-21 | 2021-06-15 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
US11950616B2 (en) | 2019-06-21 | 2024-04-09 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
JP7010509B2 (ja) * | 2020-01-15 | 2022-01-26 | 一般社団法人 Unical | 新規配合スポーツ飲料およびその調製のための顆粒剤 |
CA3170624A1 (en) | 2020-03-05 | 2021-09-10 | VitaNav, Inc. | Composition of (d)-.beta.-hydroxybutyric acid, (d)-.beta.-hydroxyvalericacid, and (d)-1,3 butanediol as a nutritional supplement and therapeuticagent |
WO2023167989A2 (en) * | 2022-03-04 | 2023-09-07 | Guardian Biosciences, LLC | Compositions and methods to promote brain health |
WO2023183545A1 (en) * | 2022-03-24 | 2023-09-28 | Cerecin Inc. | Systems, methods, and devices for predicting pharmacokinetic influences on ketogenesis following administration of tricaprilin |
US11969430B1 (en) | 2023-03-10 | 2024-04-30 | Axcess Global Sciences, Llc | Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance |
Family Cites Families (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2766146A (en) | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US2766145A (en) | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US3053677A (en) | 1959-11-12 | 1962-09-11 | Eastman Kodak Co | Petroleum wax for paper coatings |
US4346107A (en) | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
FR2490631A1 (fr) | 1980-09-24 | 1982-03-26 | Roussel Uclaf | Nouvelle composition lipidique utilisable en dietetique, reanimation et therapeutique |
US4528197A (en) | 1983-01-26 | 1985-07-09 | Kabivitrum Ab | Controlled triglyceride nutrition for hypercatabolic mammals |
US4551523A (en) | 1983-04-14 | 1985-11-05 | Eastman Kodak Company | Preparation of saccharide acetoacetates |
US4847296A (en) | 1984-09-13 | 1989-07-11 | Babayan Vigen K | Triglyceride preparations for the prevention of catabolism |
US5126373A (en) | 1987-11-19 | 1992-06-30 | Henri Brunengraber | Composition for parenteral and oral nutrition |
SE8803141L (sv) * | 1988-09-07 | 1990-03-08 | Kabivitrum Ab | Naeringsmedel foer maenniskor och djur |
US5650148A (en) | 1988-12-15 | 1997-07-22 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system |
DE3843238C1 (pt) | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
IT1240775B (it) | 1990-02-23 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma. |
JP3226217B2 (ja) | 1990-04-26 | 2001-11-05 | ザ、プロクター、エンド、ギャンブル、カンパニー | ポリオール脂肪酸ポリエステルを含有したショートニング組成物 |
US5385915A (en) | 1990-05-16 | 1995-01-31 | The Rockefeller University | Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation |
US5538983A (en) | 1990-05-16 | 1996-07-23 | The Rockefeller University | Method of treating amyloidosis by modulation of calcium |
US5614560A (en) | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
GB9113484D0 (en) | 1991-06-21 | 1991-08-07 | Unilever Plc | Cosmetic composition |
US5276059A (en) | 1992-07-10 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of diseases associated with amyloid formation |
US5308832A (en) | 1992-07-27 | 1994-05-03 | Abbott Laboratories | Nutritional product for persons having a neurological injury |
DE69333461T2 (de) | 1992-10-13 | 2005-03-24 | Duke University | VERFAHREN ZUM nachweis der Alzheimer Krankheit |
JP3486778B2 (ja) | 1993-04-02 | 2004-01-13 | 三菱ウェルファーマ株式会社 | アルツハイマー病予防治療剤 |
IL110309A0 (en) * | 1993-07-15 | 1994-10-21 | Univ Kentucky Res Found | A method of protecting against neuron loss |
WO1995009145A1 (en) * | 1993-09-30 | 1995-04-06 | Eastman Chemical Company | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES |
US5420335A (en) | 1993-09-30 | 1995-05-30 | Birkhahn; Ronald H. | Parenteral nutrients based on watersoluble glycerol bisacetoacetates |
US5438042B1 (en) | 1993-10-08 | 1997-08-26 | Sandoz Nutrition Ltd | Enteral nutritional composition having amino acid profile |
JP3645580B2 (ja) | 1993-10-22 | 2005-05-11 | 株式会社フジモト・ブラザーズ | グルコースエステル誘導体を含有する脳代謝改善剤 |
US5691325A (en) * | 1994-01-14 | 1997-11-25 | Sandyk; Reuven | Method for ameliorating age-related disease conditions |
US7049078B2 (en) | 1994-04-27 | 2006-05-23 | Judés Poirier | Apolipoprotein E polymorphism and treatment of alzheimer's disease |
GB9408465D0 (en) | 1994-04-27 | 1994-06-22 | Univ Mcgill | Apolipoprotein e polymorphism & treatment of alzheimer's disease |
US5607967A (en) | 1994-10-27 | 1997-03-04 | Merck & Co., Inc. | Treatment of alzheimer's disease with 5-(tetradecyloxy)-2-furan carboxylic acid |
CA2235350C (en) | 1994-11-08 | 2009-01-06 | Avicena Group, Inc. | Use of creatine or creatine analogs for the treatment of diseases of the nervous system |
US5854215A (en) | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
US5817626A (en) | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
US6022683A (en) | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
JP4598203B2 (ja) | 1995-12-01 | 2010-12-15 | ビーティージー・インターナショナル・リミテッド | 脳機能改善剤 |
US5936078A (en) | 1995-12-12 | 1999-08-10 | Kyowa Hakko Kogyo Co., Ltd. | DNA and protein for the diagnosis and treatment of Alzheimer's disease |
DE19609476A1 (de) | 1996-03-11 | 1997-09-18 | Basf Ag | Stabile zur parenteralen Verabreichung geeignete Carotinoid-Emulsionen |
IT1284650B1 (it) | 1996-05-24 | 1998-05-21 | Sigma Tau Ind Farmaceuti | Farmaco a base di un derivato della carnitina per il trattamento della demenza di alzheimer in pazienti ad insorgenza precoce della patologia |
KR980008239A (ko) | 1996-07-26 | 1998-04-30 | 김충환 | 사이클로스포린-함유 약학적 조성물 |
EP1006794B1 (en) | 1997-03-12 | 2007-11-28 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
US6323237B1 (en) | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
US6316038B1 (en) | 1997-03-17 | 2001-11-13 | Btg International Limited | Therapeutic compositions |
DK1017379T3 (en) | 1997-03-17 | 2015-02-16 | Btg Int Ltd | Therapeutic compositions comprising ketone compounds and precursors thereof |
US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
US20040058873A1 (en) | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
EP1065931A4 (en) | 1998-04-02 | 2006-10-11 | Avicena Group Inc | COMPOSITIONS CONTAINING CREATINE COMBINED WITH A SECOND AGENT |
US6380244B2 (en) | 1998-07-22 | 2002-04-30 | Metabolix, Inc. | Nutritional and therapeutic uses of 3-hydroxyalkanoate oligomers |
CN1313895A (zh) | 1998-09-14 | 2001-09-19 | 泛太平洋制药公司 | 蜂毒蛋白的有用特性和编码这种蜂毒蛋白的基因 |
DK1123094T3 (da) | 1998-09-15 | 2007-08-20 | Btg Int Ltd | Terapeutiske præparater (II) |
GB9908202D0 (en) | 1999-04-12 | 1999-06-02 | Unilever Plc | Cosmetic compositions |
WO2001082928A1 (en) | 2000-05-01 | 2001-11-08 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
US20070179197A1 (en) | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
DE20012857U1 (de) | 2000-07-27 | 2000-11-09 | Sportmedizin Team Vertriebs Gmbh, Berneck | Diätetisches Lebensmittel zum Fettabbau |
US6667397B2 (en) | 2000-08-25 | 2003-12-23 | Eastman Chemical Company | Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom |
GB2368011A (en) | 2000-10-17 | 2002-04-24 | Unilever Plc | Fatty acid esters of maltose and uses thereof |
US20020103139A1 (en) | 2000-12-01 | 2002-08-01 | M. Weisspapir | Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control |
KR100479741B1 (ko) | 2000-12-30 | 2005-03-30 | 주식회사 엘지생활건강 | 글루코오스 아실화 유도체 또는 수크로오스 아실화유도체를 함유하는 피부미백제 |
JP2004534050A (ja) | 2001-06-07 | 2004-11-11 | エーザイ株式会社 | 細胞ストレスに関連する疾病及び状態を予防及び治療する方法 |
JP2003048831A (ja) * | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
AU2002336759A1 (en) | 2001-09-21 | 2003-04-14 | Accera, Inc. | Drug targets for alzheimer's disease and other diseases associated with decreased neuronal metabolism |
AU2003268235A1 (en) | 2002-09-09 | 2004-03-29 | Mitochroma Research, Inc. | Compositions and methods for treating niddm and other conditions and disorders associated with ampk regulation |
US6884454B2 (en) | 2002-10-21 | 2005-04-26 | Julio Lionel Pimentel | Appetite suppressing diet bar |
JP3660997B2 (ja) * | 2002-11-26 | 2005-06-15 | 独立行政法人情報通信研究機構 | 3次元電界分布測定方法および3次元電界分布測定装置 |
US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
CN1756554A (zh) | 2003-03-06 | 2006-04-05 | 艾克塞拉公司 | 新的化学实体和它们用于治疗代谢障碍的方法 |
ES2670413T3 (es) | 2003-06-03 | 2018-05-30 | The United States Government As Represented By The Department Of Health And Human Services | Suplementos nutricionales y composiciones terapéuticas que comprenden derivados de (R)-3-hidroxibutirato |
US20050013884A1 (en) | 2003-07-16 | 2005-01-20 | Rennels M. Scott | Compositions and methods for treating heart disease |
US7148192B2 (en) * | 2004-01-29 | 2006-12-12 | Ebwe Pharma Ges. M.H. Nfg.Kg | Neuroprotective dietary supplement |
US20060252775A1 (en) | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
US8227408B2 (en) | 2005-09-07 | 2012-07-24 | Neurotez, Inc. | Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology |
HUE037129T2 (hu) * | 2005-12-15 | 2018-08-28 | Nestec Sa | Kompozíciók és eljárások agyi funkció megõrzésére |
ES2645816T3 (es) | 2006-04-03 | 2017-12-07 | Accera, Inc. | Uso de compuestos cetogénicos para el tratamiento de la alteración de la memoria asociada a la edad |
US7807718B2 (en) | 2006-06-30 | 2010-10-05 | Sami A. Hashim | Glyceride esters for the treatment of diseases associated with reduced neuronal metabolism of glucose |
-
2007
- 2007-04-03 ES ES12160599.2T patent/ES2645816T3/es active Active
- 2007-04-03 DK DK12160599.2T patent/DK2500017T3/da active
- 2007-04-03 DK DK07797196.8T patent/DK2001293T3/en active
- 2007-04-03 KR KR1020157002435A patent/KR101634083B1/ko active IP Right Grant
- 2007-04-03 ES ES07797196T patent/ES2697504T3/es active Active
- 2007-04-03 HU HUE07797196A patent/HUE040002T2/hu unknown
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- 2007-04-03 HU HUE12160599A patent/HUE035852T2/en unknown
- 2007-04-03 LT LTEP12160599.2T patent/LT2500017T/lt unknown
- 2007-04-03 LT LTEP07797196.8T patent/LT2001293T/lt unknown
- 2007-04-03 WO PCT/US2007/065873 patent/WO2007115282A2/en active Application Filing
- 2007-04-03 JP JP2009504423A patent/JP2009532496A/ja active Pending
- 2007-04-03 EP EP07797196.8A patent/EP2001293B9/en active Active
- 2007-04-03 PT PT121605992T patent/PT2500017T/pt unknown
- 2007-04-03 SI SI200732064T patent/SI2001293T1/sl unknown
- 2007-04-03 KR KR1020087010466A patent/KR20090003148A/ko active Application Filing
- 2007-04-03 US US12/064,850 patent/US8124589B2/en not_active Expired - Fee Related
- 2007-04-03 PT PT07797196T patent/PT2001293T/pt unknown
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2012
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- 2012-12-06 JP JP2012267035A patent/JP5847693B2/ja active Active
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Also Published As
Publication number | Publication date |
---|---|
PT2001293T (pt) | 2018-11-28 |
SI2001293T1 (sl) | 2018-12-31 |
ES2645816T3 (es) | 2017-12-07 |
JP2009532496A (ja) | 2009-09-10 |
JP2018080175A (ja) | 2018-05-24 |
KR101634083B1 (ko) | 2016-06-28 |
JP5847693B2 (ja) | 2016-01-27 |
WO2007115282A3 (en) | 2007-12-21 |
LT2500017T (lt) | 2017-12-11 |
US20120122978A1 (en) | 2012-05-17 |
JP2013082716A (ja) | 2013-05-09 |
HUE040002T2 (hu) | 2019-02-28 |
EP2001293B1 (en) | 2018-08-29 |
KR20090003148A (ko) | 2009-01-09 |
US8124589B2 (en) | 2012-02-28 |
DK2500017T3 (da) | 2017-11-06 |
DK2001293T3 (en) | 2018-11-19 |
US20140256808A1 (en) | 2014-09-11 |
LT2001293T (lt) | 2018-11-12 |
WO2007115282A2 (en) | 2007-10-11 |
ES2697504T3 (es) | 2019-01-24 |
EP2500017A1 (en) | 2012-09-19 |
EP2001293B9 (en) | 2019-04-17 |
HUE035852T2 (en) | 2018-05-28 |
EP2001293A2 (en) | 2008-12-17 |
EP2500017B1 (en) | 2017-09-06 |
US8748400B2 (en) | 2014-06-10 |
JP2016121128A (ja) | 2016-07-07 |
US20080287372A1 (en) | 2008-11-20 |
KR20150018897A (ko) | 2015-02-24 |
EP2001293A4 (en) | 2009-09-23 |
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