LT2001293T - Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymui - Google Patents
Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymuiInfo
- Publication number
- LT2001293T LT2001293T LTEP07797196.8T LT07797196T LT2001293T LT 2001293 T LT2001293 T LT 2001293T LT 07797196 T LT07797196 T LT 07797196T LT 2001293 T LT2001293 T LT 2001293T
- Authority
- LT
- Lithuania
- Prior art keywords
- age
- treatment
- associated memory
- memory impairment
- ketogenic compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74414006P | 2006-04-03 | 2006-04-03 | |
PCT/US2007/065873 WO2007115282A2 (en) | 2006-04-03 | 2007-04-03 | Use of ketogenic compounds for treatment of age-associated memory impairment |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2001293T true LT2001293T (lt) | 2018-11-12 |
Family
ID=38564302
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP12160599.2T LT2500017T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas senatvinio atminties susilpnėjimo gydymui |
LTEP07797196.8T LT2001293T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymui |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP12160599.2T LT2500017T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas senatvinio atminties susilpnėjimo gydymui |
Country Status (11)
Country | Link |
---|---|
US (3) | US8124589B2 (lt) |
EP (2) | EP2001293B9 (lt) |
JP (4) | JP2009532496A (lt) |
KR (2) | KR20090003148A (lt) |
DK (2) | DK2001293T3 (lt) |
ES (2) | ES2697504T3 (lt) |
HU (2) | HUE035852T2 (lt) |
LT (2) | LT2500017T (lt) |
PT (2) | PT2500017T (lt) |
SI (1) | SI2001293T1 (lt) |
WO (1) | WO2007115282A2 (lt) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
DE60138019D1 (de) * | 2000-05-01 | 2009-04-30 | Accera Inc | Verwendung von triglyceriden mit mittellangen ketten zur behandlung und vorbeugung der alzheimerschen erkrankung |
US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
US20060280721A1 (en) | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
WO2007001883A2 (en) * | 2005-06-20 | 2007-01-04 | Accera, Inc. | Method to reduce oxidative damage and improve mitochondrial efficiency |
TR201807470T4 (tr) * | 2005-12-15 | 2018-06-21 | Nestec Sa | Beyin fonksiyonlarını korumak için bileşimler ve yöntemler. |
EP2001293B9 (en) | 2006-04-03 | 2019-04-17 | Accera, Inc. | Use of ketogenic compounds for treatment of age-associated memory impairment |
EP1929995A1 (en) | 2006-12-04 | 2008-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anaplerotic therapy of Huntington disease and other polyglutamine diseases |
EP2150265A4 (en) * | 2007-05-14 | 2010-06-09 | Neuera Pharmaceuticals Inc | INHIBITORS OF ACETYL-COA-CARBOXYLASE FOR THE TREATMENT OF NEURONAL HYPOMETABOLISM |
EP2650381B1 (en) | 2007-07-31 | 2016-09-21 | Accera, Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
CN106038532B (zh) | 2008-01-04 | 2019-05-14 | 牛津大学科技创新有限公司 | 用作降低血脂药剂的酮体和酮体酯 |
CN105267969A (zh) * | 2008-01-04 | 2016-01-27 | 雀巢产品技术援助有限公司 | 包含不饱和脂肪酸和一氧化氮释放化合物的组合物及其用于增强认知和相关功能的用途 |
US8105809B2 (en) * | 2008-07-03 | 2012-01-31 | Accera, Inc. | Enzymatic synthesis of acetoacetate esters and derivatives |
CN102105071A (zh) | 2008-07-03 | 2011-06-22 | 艾克塞拉公司 | 用于治疗神经性障碍的乙酰乙酸的单甘油酯及其衍生物 |
BRPI0916228A2 (pt) * | 2008-07-18 | 2015-11-03 | Dart Neuroscience Llc | métodos e sistemas para avaliação de agentes de memória |
US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
ES2544589T3 (es) | 2008-11-06 | 2015-09-01 | The Nisshin Oillio Group, Ltd. | Alimento líquido concentrado |
EP2519234B1 (en) | 2009-12-30 | 2017-06-28 | Baylor Research Institute | Anaplerotic therapy for alzheimer's disease |
GB201002983D0 (en) * | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
RU2012145109A (ru) * | 2010-03-24 | 2014-04-27 | Нестек С.А. | Способ повышения вкусовой привлекательности съедобных композиций |
EP3659595A1 (en) | 2012-11-05 | 2020-06-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Ketone bodies to protect tissues from damage by ionizing radiation |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
ES2728727T3 (es) | 2012-12-13 | 2019-10-28 | Baylor Res Institute At Dallas | Triheptanoína para el tratamiento de la deficiencia del transportador de glucosa 1 |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
WO2014140308A1 (en) | 2013-03-14 | 2014-09-18 | Isis Innovation Ltd | Process for producing (r)-3-hydroxybutyl (r)-3-hydroxybutyrate |
KR102499654B1 (ko) | 2013-03-19 | 2023-02-13 | 유니버시티 오브 사우스 플로리다 | 상승되고 지속되는 케톤증을 생성하기 위한 조성물 및 방법 |
ES2774321T3 (es) | 2013-11-14 | 2020-07-20 | Univ Queensland | Trastornos neurodegenerativos y métodos de tratamiento y diagnóstico de los mismos |
AU2015290597B2 (en) * | 2014-07-17 | 2017-07-20 | The Nisshin Oillio Group, Ltd. | Baked confectionery that substantially includes no flour |
TWI722992B (zh) * | 2014-07-23 | 2021-04-01 | 一般財團法人糧食研究會 | 腦功能改善劑、及認知功能障礙的預防或治療劑 |
ES2761826T3 (es) | 2014-12-08 | 2020-05-21 | Nestle Sa | Composiciones que contienen triglicéridos de cadena media para su uso en el tratamiento de la epilepsia |
US10668041B2 (en) | 2014-12-08 | 2020-06-02 | Societe Des Produits Nestle Sa | Compositions and methods comprising medium chain triglycerides for treatment of epilepsy |
JP6446265B2 (ja) * | 2014-12-26 | 2018-12-26 | 花王株式会社 | 固形状組成物 |
US10786476B2 (en) | 2016-02-23 | 2020-09-29 | Imbria Pharmaceuticals, Inc. | Combination therapy |
US11185518B2 (en) | 2017-12-19 | 2021-11-30 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer |
US10245242B1 (en) | 2017-11-22 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10596130B2 (en) | 2017-12-19 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US10973792B2 (en) | 2019-02-13 | 2021-04-13 | Axcess Global Sciences, Llc | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use |
US11241403B2 (en) | 2016-03-11 | 2022-02-08 | Axcess Global Sciences, Llc | Beta-hydroxybutyrate mixed salt compositions and methods of use |
US11103470B2 (en) | 2017-11-22 | 2021-08-31 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10245243B1 (en) | 2017-12-19 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US10596129B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10596131B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10973786B2 (en) | 2016-03-11 | 2021-04-13 | Axcess Global Sciences, Llc | R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions |
US10736861B2 (en) | 2016-03-11 | 2020-08-11 | Axcess Global Sciences, Llc | Mixed salt compositions for producing elevated and sustained ketosis |
US10292952B2 (en) | 2016-03-11 | 2019-05-21 | Axcess Global Sciences, Llc | Mixed salt compositions for maintaining or restoring electrolyte balance while producing elevated and sustained ketosis |
CN109069534B (zh) * | 2016-04-15 | 2021-04-20 | 广川庆裕 | 认知功能改善剂 |
JP6935994B2 (ja) | 2016-08-19 | 2021-09-15 | 株式会社明治 | ケトン体生成促進用組成物 |
AU2017347778A1 (en) * | 2016-10-24 | 2019-05-16 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
US20180177753A1 (en) | 2016-12-23 | 2018-06-28 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for migraine symptom management |
US9925164B1 (en) | 2017-01-12 | 2018-03-27 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for traumatic brain injury |
US10376528B2 (en) | 2017-03-10 | 2019-08-13 | Tecton Group, Llc | Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor |
JP6895144B2 (ja) * | 2017-04-05 | 2021-06-30 | 北海道公立大学法人 札幌医科大学 | 診断支援システム、診断支援システムの作動方法、及びプログラム |
US10957290B2 (en) * | 2017-08-31 | 2021-03-23 | Spotify Ab | Lyrics analyzer |
US11202769B2 (en) | 2017-11-22 | 2021-12-21 | Axcess Global Sciences, Llc | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function |
US10925843B2 (en) | 2018-04-18 | 2021-02-23 | Axcess Global Sciences, Llc | Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate |
US11944598B2 (en) | 2017-12-19 | 2024-04-02 | Axcess Global Sciences, Llc | Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer |
US11241401B2 (en) | 2020-02-06 | 2022-02-08 | Axcess Global Sciences, Llc | Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions |
US11806324B2 (en) | 2018-04-18 | 2023-11-07 | Axcess Global Sciences, Llc | Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies |
US10980772B2 (en) | 2018-08-27 | 2021-04-20 | Axcess Global Sciences, Llc | Compositions and methods for delivering tetrahydrocannabinol and ketone bodies |
US11129802B2 (en) | 2018-08-27 | 2021-09-28 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
US10512615B1 (en) | 2018-08-27 | 2019-12-24 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
US11419836B2 (en) | 2019-02-13 | 2022-08-23 | Axcess Global Sciences, Llc | Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions |
EP3810119A2 (en) * | 2018-06-21 | 2021-04-28 | Société des Produits Nestlé S.A. | <sup2/>? <sub2/>?+? ?compositions and methods using a nicotinamide adenine dinucleotide (nad) precursor and at least one ketone or ketone precursor |
AU2020221569A1 (en) * | 2019-02-11 | 2021-09-02 | Axcess Global Sciences, Llc | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use |
AU2020221916A1 (en) * | 2019-02-11 | 2021-09-02 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer |
WO2020180980A1 (en) * | 2019-03-04 | 2020-09-10 | Cerecin Inc. | Medium chain triglyceride formulations with improved bioavailiblity and methods related thereto |
JP7458620B2 (ja) * | 2019-06-21 | 2024-04-01 | 株式会社大塚製薬工場 | 栄養組成物 |
US11950616B2 (en) | 2019-06-21 | 2024-04-09 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
US11033553B2 (en) | 2019-06-21 | 2021-06-15 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
JP7010509B2 (ja) * | 2020-01-15 | 2022-01-26 | 一般社団法人 Unical | 新規配合スポーツ飲料およびその調製のための顆粒剤 |
WO2021178547A1 (en) | 2020-03-05 | 2021-09-10 | Devon Price | COMPOSITION OF (D)-β-HYDROXYBUTYRIC ACID, (D)-β-HYDROXYVALERIC ACID, AND (D)-1,3 BUTANEDIOL AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT |
WO2023167989A2 (en) * | 2022-03-04 | 2023-09-07 | Guardian Biosciences, LLC | Compositions and methods to promote brain health |
WO2023183545A1 (en) * | 2022-03-24 | 2023-09-28 | Cerecin Inc. | Systems, methods, and devices for predicting pharmacokinetic influences on ketogenesis following administration of tricaprilin |
US11969430B1 (en) | 2023-03-10 | 2024-04-30 | Axcess Global Sciences, Llc | Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance |
Family Cites Families (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2766145A (en) * | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US2766146A (en) * | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US3053677A (en) * | 1959-11-12 | 1962-09-11 | Eastman Kodak Co | Petroleum wax for paper coatings |
US4346107A (en) * | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
FR2490631A1 (fr) * | 1980-09-24 | 1982-03-26 | Roussel Uclaf | Nouvelle composition lipidique utilisable en dietetique, reanimation et therapeutique |
US4528197A (en) * | 1983-01-26 | 1985-07-09 | Kabivitrum Ab | Controlled triglyceride nutrition for hypercatabolic mammals |
US4551523A (en) * | 1983-04-14 | 1985-11-05 | Eastman Kodak Company | Preparation of saccharide acetoacetates |
US4847296A (en) * | 1984-09-13 | 1989-07-11 | Babayan Vigen K | Triglyceride preparations for the prevention of catabolism |
US5126373A (en) | 1987-11-19 | 1992-06-30 | Henri Brunengraber | Composition for parenteral and oral nutrition |
SE8803141L (sv) * | 1988-09-07 | 1990-03-08 | Kabivitrum Ab | Naeringsmedel foer maenniskor och djur |
US5650148A (en) * | 1988-12-15 | 1997-07-22 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system |
DE3843238C1 (lt) * | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
IT1240775B (it) | 1990-02-23 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma. |
DK0531306T3 (da) | 1990-04-26 | 1995-05-29 | Procter & Gamble | Shorteningsammensætninger indeholdende polyolfedtsyrepolyestere |
US5385915A (en) * | 1990-05-16 | 1995-01-31 | The Rockefeller University | Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation |
US5538983A (en) * | 1990-05-16 | 1996-07-23 | The Rockefeller University | Method of treating amyloidosis by modulation of calcium |
US5614560A (en) * | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
GB9113484D0 (en) | 1991-06-21 | 1991-08-07 | Unilever Plc | Cosmetic composition |
US5276059A (en) * | 1992-07-10 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of diseases associated with amyloid formation |
US5308832A (en) * | 1992-07-27 | 1994-05-03 | Abbott Laboratories | Nutritional product for persons having a neurological injury |
ATE262592T1 (de) * | 1992-10-13 | 2004-04-15 | Univ Duke | Verfahren zum nachweis der alzheimer krankheit |
JP3486778B2 (ja) | 1993-04-02 | 2004-01-13 | 三菱ウェルファーマ株式会社 | アルツハイマー病予防治療剤 |
IL110309A0 (en) * | 1993-07-15 | 1994-10-21 | Univ Kentucky Res Found | A method of protecting against neuron loss |
WO1995009145A1 (en) * | 1993-09-30 | 1995-04-06 | Eastman Chemical Company | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES |
US5420335A (en) | 1993-09-30 | 1995-05-30 | Birkhahn; Ronald H. | Parenteral nutrients based on watersoluble glycerol bisacetoacetates |
US5438042B1 (en) * | 1993-10-08 | 1997-08-26 | Sandoz Nutrition Ltd | Enteral nutritional composition having amino acid profile |
JP3645580B2 (ja) | 1993-10-22 | 2005-05-11 | 株式会社フジモト・ブラザーズ | グルコースエステル誘導体を含有する脳代謝改善剤 |
US5691325A (en) * | 1994-01-14 | 1997-11-25 | Sandyk; Reuven | Method for ameliorating age-related disease conditions |
US7049078B2 (en) * | 1994-04-27 | 2006-05-23 | Judés Poirier | Apolipoprotein E polymorphism and treatment of alzheimer's disease |
GB9408465D0 (en) * | 1994-04-27 | 1994-06-22 | Univ Mcgill | Apolipoprotein e polymorphism & treatment of alzheimer's disease |
US5607967A (en) | 1994-10-27 | 1997-03-04 | Merck & Co., Inc. | Treatment of alzheimer's disease with 5-(tetradecyloxy)-2-furan carboxylic acid |
EP2327404A1 (en) | 1994-11-08 | 2011-06-01 | Avicena Group, Inc. | Use of creatine or creatine analogs for the treatment of diseases of the nervous system |
US5854215A (en) * | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
EP0815134B1 (en) * | 1995-03-14 | 2002-06-05 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
US5817626A (en) * | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
US6022683A (en) * | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
JP4598203B2 (ja) * | 1995-12-01 | 2010-12-15 | ビーティージー・インターナショナル・リミテッド | 脳機能改善剤 |
US5936078A (en) * | 1995-12-12 | 1999-08-10 | Kyowa Hakko Kogyo Co., Ltd. | DNA and protein for the diagnosis and treatment of Alzheimer's disease |
DE19609476A1 (de) * | 1996-03-11 | 1997-09-18 | Basf Ag | Stabile zur parenteralen Verabreichung geeignete Carotinoid-Emulsionen |
IT1284650B1 (it) | 1996-05-24 | 1998-05-21 | Sigma Tau Ind Farmaceuti | Farmaco a base di un derivato della carnitina per il trattamento della demenza di alzheimer in pazienti ad insorgenza precoce della patologia |
KR980008239A (ko) * | 1996-07-26 | 1998-04-30 | 김충환 | 사이클로스포린-함유 약학적 조성물 |
EP1006794B1 (en) * | 1997-03-12 | 2007-11-28 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
AU749638B2 (en) * | 1997-03-17 | 2002-06-27 | Btg International Limited | Therapeutic compositions |
US6316038B1 (en) * | 1997-03-17 | 2001-11-13 | Btg International Limited | Therapeutic compositions |
US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
EP1065931A4 (en) | 1998-04-02 | 2006-10-11 | Avicena Group Inc | COMPOSITIONS CONTAINING CREATINE COMBINED WITH A SECOND AGENT |
ES2234276T3 (es) | 1998-07-22 | 2005-06-16 | Metabolix, Inc. | Utilizaciones nutricionales y terapeuticas de oligomeros de 3-hidroxialcanoato. |
US6395306B1 (en) * | 1998-09-14 | 2002-05-28 | Pan Pacific Pharmaceuticals, Inc. | Bee venom protein and gene encoding same |
EP1123094B1 (en) | 1998-09-15 | 2007-04-11 | Btg International Limited | Therapeutic compositions (ii) |
GB9908202D0 (en) | 1999-04-12 | 1999-06-02 | Unilever Plc | Cosmetic compositions |
US6835750B1 (en) * | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
US20070179197A1 (en) | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
DE60138019D1 (de) * | 2000-05-01 | 2009-04-30 | Accera Inc | Verwendung von triglyceriden mit mittellangen ketten zur behandlung und vorbeugung der alzheimerschen erkrankung |
DE20012857U1 (de) * | 2000-07-27 | 2000-11-09 | Sportmedizin Team Vertriebs Gm | Diätetisches Lebensmittel zum Fettabbau |
US6667397B2 (en) | 2000-08-25 | 2003-12-23 | Eastman Chemical Company | Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom |
GB2368011A (en) | 2000-10-17 | 2002-04-24 | Unilever Plc | Fatty acid esters of maltose and uses thereof |
US20020103139A1 (en) * | 2000-12-01 | 2002-08-01 | M. Weisspapir | Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control |
KR100479741B1 (ko) | 2000-12-30 | 2005-03-30 | 주식회사 엘지생활건강 | 글루코오스 아실화 유도체 또는 수크로오스 아실화유도체를 함유하는 피부미백제 |
US7087649B2 (en) | 2001-06-07 | 2006-08-08 | Eisai Co., Ltd. | Methods for preventing and treating diseases and conditions associated with cellular stress |
JP2003048831A (ja) * | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
WO2003028631A2 (en) * | 2001-09-21 | 2003-04-10 | Accera, Inc. | Drug targets for alzheimer's disease and other diseases associated with decreased neuronal metabolism |
AU2003268235A1 (en) * | 2002-09-09 | 2004-03-29 | Mitochroma Research, Inc. | Compositions and methods for treating niddm and other conditions and disorders associated with ampk regulation |
US6884454B2 (en) * | 2002-10-21 | 2005-04-26 | Julio Lionel Pimentel | Appetite suppressing diet bar |
JP3660997B2 (ja) * | 2002-11-26 | 2005-06-15 | 独立行政法人情報通信研究機構 | 3次元電界分布測定方法および3次元電界分布測定装置 |
US20050031651A1 (en) * | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
US20060189545A1 (en) | 2003-03-06 | 2006-08-24 | Henderson Samuel T | Novel chemical entities and methods for their use in treatment of metabolic disorders |
US20060280721A1 (en) * | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
US20050013884A1 (en) * | 2003-07-16 | 2005-01-20 | Rennels M. Scott | Compositions and methods for treating heart disease |
US7148192B2 (en) * | 2004-01-29 | 2006-12-12 | Ebwe Pharma Ges. M.H. Nfg.Kg | Neuroprotective dietary supplement |
US20060252775A1 (en) | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
US8227408B2 (en) | 2005-09-07 | 2012-07-24 | Neurotez, Inc. | Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology |
TR201807470T4 (tr) * | 2005-12-15 | 2018-06-21 | Nestec Sa | Beyin fonksiyonlarını korumak için bileşimler ve yöntemler. |
EP2001293B9 (en) | 2006-04-03 | 2019-04-17 | Accera, Inc. | Use of ketogenic compounds for treatment of age-associated memory impairment |
WO2008005818A1 (en) | 2006-06-30 | 2008-01-10 | Stepan Co | Glyceride esters for the treatment of diseases associated with reduced neuronal metabolism of glucose |
-
2007
- 2007-04-03 EP EP07797196.8A patent/EP2001293B9/en active Active
- 2007-04-03 LT LTEP12160599.2T patent/LT2500017T/lt unknown
- 2007-04-03 ES ES07797196T patent/ES2697504T3/es active Active
- 2007-04-03 DK DK07797196.8T patent/DK2001293T3/en active
- 2007-04-03 HU HUE12160599A patent/HUE035852T2/en unknown
- 2007-04-03 HU HUE07797196A patent/HUE040002T2/hu unknown
- 2007-04-03 DK DK12160599.2T patent/DK2500017T3/da active
- 2007-04-03 SI SI200732064T patent/SI2001293T1/sl unknown
- 2007-04-03 KR KR1020087010466A patent/KR20090003148A/ko active Application Filing
- 2007-04-03 PT PT121605992T patent/PT2500017T/pt unknown
- 2007-04-03 WO PCT/US2007/065873 patent/WO2007115282A2/en active Application Filing
- 2007-04-03 KR KR1020157002435A patent/KR101634083B1/ko active IP Right Grant
- 2007-04-03 LT LTEP07797196.8T patent/LT2001293T/lt unknown
- 2007-04-03 ES ES12160599.2T patent/ES2645816T3/es active Active
- 2007-04-03 EP EP12160599.2A patent/EP2500017B1/en active Active
- 2007-04-03 US US12/064,850 patent/US8124589B2/en not_active Expired - Fee Related
- 2007-04-03 JP JP2009504423A patent/JP2009532496A/ja active Pending
- 2007-04-03 PT PT07797196T patent/PT2001293T/pt unknown
-
2012
- 2012-01-25 US US13/358,257 patent/US8748400B2/en not_active Expired - Fee Related
- 2012-12-06 JP JP2012267035A patent/JP5847693B2/ja active Active
-
2014
- 2014-05-05 US US14/269,453 patent/US20140256808A1/en not_active Abandoned
-
2015
- 2015-11-25 JP JP2015229243A patent/JP2016121128A/ja not_active Withdrawn
-
2017
- 2017-12-18 JP JP2017241367A patent/JP2018080175A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20080287372A1 (en) | 2008-11-20 |
PT2001293T (pt) | 2018-11-28 |
WO2007115282A2 (en) | 2007-10-11 |
HUE040002T2 (hu) | 2019-02-28 |
KR101634083B1 (ko) | 2016-06-28 |
DK2500017T3 (da) | 2017-11-06 |
EP2500017A1 (en) | 2012-09-19 |
KR20090003148A (ko) | 2009-01-09 |
ES2697504T3 (es) | 2019-01-24 |
US20120122978A1 (en) | 2012-05-17 |
EP2001293B1 (en) | 2018-08-29 |
US20140256808A1 (en) | 2014-09-11 |
JP2013082716A (ja) | 2013-05-09 |
US8124589B2 (en) | 2012-02-28 |
PT2500017T (pt) | 2017-11-14 |
JP2009532496A (ja) | 2009-09-10 |
LT2500017T (lt) | 2017-12-11 |
EP2001293A4 (en) | 2009-09-23 |
JP2018080175A (ja) | 2018-05-24 |
ES2645816T3 (es) | 2017-12-07 |
WO2007115282A3 (en) | 2007-12-21 |
DK2001293T3 (en) | 2018-11-19 |
JP5847693B2 (ja) | 2016-01-27 |
KR20150018897A (ko) | 2015-02-24 |
JP2016121128A (ja) | 2016-07-07 |
US8748400B2 (en) | 2014-06-10 |
EP2001293B9 (en) | 2019-04-17 |
EP2500017B1 (en) | 2017-09-06 |
SI2001293T1 (sl) | 2018-12-31 |
HUE035852T2 (en) | 2018-05-28 |
EP2001293A2 (en) | 2008-12-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT2001293T (pt) | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade | |
IL248204A0 (en) | Combined treatment of tumors expressing 38cd | |
GB0610867D0 (en) | Treatment of pain | |
EP2066589A4 (en) | WATER TREATMENT SYSTEM | |
EP1982660A4 (en) | TREATMENT ENDOSCOPE | |
EP2022433A4 (en) | ENDOSCOPE TREATMENT SYSTEM | |
IL193748A0 (en) | Treatment of pain | |
EP2049139A4 (en) | TREATMENT OF TUMORS EXPRESSING RAS | |
HK1129600A1 (en) | Treatment of excessive neovascularization | |
ZA201001264B (en) | 1-amino-alkylcycohxane derivatives for the treatment of cochleat tinnitus | |
GB0909297D0 (en) | Composition for the treatment of skin conditions | |
GB0715790D0 (en) | Drug combination for the treatment of sialorrhoea | |
IL192933A0 (en) | Benzoisoindole derivatives for the treatment of pain | |
GB0610868D0 (en) | Treatment of pain | |
IL194066A0 (en) | Therapeutic composition for treatment of tinnitus | |
GB0723100D0 (en) | Treatment of HFnEF | |
EP2271328A4 (en) | ANTISEPTIC COMPOSITIONS FOR THE TREATMENT OF INFECTIONS | |
EP2023894A4 (en) | FIXED COMBINATION DOSAGE FOR TREATING MIGRAINE | |
GB0616450D0 (en) | Treatment of pain | |
GB0624439D0 (en) | Technique for treatment of gall-and kidney-stones | |
IL184620A0 (en) | Composition for the treatment of inflammation | |
PT1879609E (pt) | Utilização de histionas para fins terapêuticos | |
IL176303A0 (en) | Pharmaceutical composition for the treatment of otomycosis | |
GB0602857D0 (en) | The treatment of sialorrhoea | |
ZA200806180B (en) | Benzoisoindole derivatives for the treatment of pain |