PT2398498T - Moléculas de anticorpo tendo especificidade para ox40 humano - Google Patents

Moléculas de anticorpo tendo especificidade para ox40 humano

Info

Publication number
PT2398498T
PT2398498T PT10744211T PT10744211T PT2398498T PT 2398498 T PT2398498 T PT 2398498T PT 10744211 T PT10744211 T PT 10744211T PT 10744211 T PT10744211 T PT 10744211T PT 2398498 T PT2398498 T PT 2398498T
Authority
PT
Portugal
Prior art keywords
specificity
human
antibody molecules
antibody
molecules
Prior art date
Application number
PT10744211T
Other languages
English (en)
Portuguese (pt)
Inventor
D G Lawson Alastair
Zhang Yi
George Popplewell Andrew
Malcolm Nesbitt Andrew
Graham Shaw Stephen
Shpektor Diana
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42634416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2398498(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of PT2398498T publication Critical patent/PT2398498T/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
PT10744211T 2009-02-17 2010-02-17 Moléculas de anticorpo tendo especificidade para ox40 humano PT2398498T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15303809P 2009-02-17 2009-02-17

Publications (1)

Publication Number Publication Date
PT2398498T true PT2398498T (pt) 2018-12-03

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ID=42634416

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10744211T PT2398498T (pt) 2009-02-17 2010-02-17 Moléculas de anticorpo tendo especificidade para ox40 humano

Country Status (35)

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US (3) US8614295B2 (he)
EP (1) EP2398498B1 (he)
JP (2) JP5782385B2 (he)
KR (1) KR101761929B1 (he)
CN (1) CN102741287B (he)
AR (1) AR075504A1 (he)
AU (1) AU2010216152B2 (he)
BR (1) BRPI1008692B8 (he)
CA (1) CA2751477C (he)
CL (1) CL2011001994A1 (he)
CO (1) CO6410312A2 (he)
CY (1) CY1121431T1 (he)
DK (1) DK2398498T3 (he)
EA (1) EA037792B1 (he)
ES (1) ES2699716T3 (he)
HK (1) HK1177470A1 (he)
HR (1) HRP20181932T1 (he)
HU (1) HUE042114T2 (he)
IL (1) IL214282A (he)
LT (1) LT2398498T (he)
MA (1) MA33122B1 (he)
MX (1) MX2011008697A (he)
MY (1) MY157473A (he)
NZ (1) NZ594315A (he)
PE (1) PE20120211A1 (he)
PL (1) PL2398498T3 (he)
PT (1) PT2398498T (he)
SG (3) SG2014014708A (he)
SI (1) SI2398498T1 (he)
TN (1) TN2011000374A1 (he)
TW (1) TWI476281B (he)
UA (1) UA107341C2 (he)
UY (1) UY32451A (he)
WO (1) WO2010096418A2 (he)
ZA (1) ZA201105500B (he)

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UY32451A (es) * 2009-02-17 2010-09-30 Ucb Pharma Sa Moléculas de anticuerpo con especifidad por el ox40 humano
GB0920127D0 (en) 2009-11-17 2009-12-30 Ucb Pharma Sa Antibodies
MX339964B (es) 2010-08-23 2016-06-17 Board Of Regents The Univ Of Texas System * Anticuerpos anti-ox40 y metodos para usarlos.
WO2013028231A1 (en) * 2011-08-23 2013-02-28 Board Of Regents, The University Of Texas System Anti-ox40 antibodies and methods of using the same
EP2655409A4 (en) 2010-12-22 2015-07-01 Univ Leland Stanford Junior SUPERAGONISTS AND ANTAGONISTS OF INTERLEUKIN-2
EA036047B1 (ru) * 2011-07-11 2020-09-18 Икнос Сайенсиз Са Антитела, которые связываются с ox40, и их применение
GB201116092D0 (en) 2011-09-16 2011-11-02 Bioceros B V Antibodies and uses thereof
UA112203C2 (uk) * 2011-11-11 2016-08-10 Юсб Фарма С.А. Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини
US9803004B2 (en) 2011-11-11 2017-10-31 Ucb Biopharma Sprl Albumin binding antibodies and binding fragments thereof
WO2013086419A1 (en) * 2011-12-09 2013-06-13 California Institute Of Technology Polymer scaffolds and their use in the treatment of vision loss
EP3508215A3 (en) 2012-12-03 2019-10-02 Bristol-Myers Squibb Company Enhancing anti-cancer activity of immunomodulatory fc fusion proteins
DK2976361T3 (en) * 2013-03-18 2018-10-01 Biocerox Prod Bv HUMANIZED ANTI-CD134- (0X40) ANTIBODIES AND APPLICATIONS THEREOF
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