PT2370575T - Integração dirigida no locus zp15 - Google Patents
Integração dirigida no locus zp15Info
- Publication number
- PT2370575T PT2370575T PT98365067T PT09836506T PT2370575T PT 2370575 T PT2370575 T PT 2370575T PT 98365067 T PT98365067 T PT 98365067T PT 09836506 T PT09836506 T PT 09836506T PT 2370575 T PT2370575 T PT 2370575T
- Authority
- PT
- Portugal
- Prior art keywords
- locus
- targeted integration
- targeted
- integration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20194608P | 2008-12-17 | 2008-12-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2370575T true PT2370575T (pt) | 2017-12-11 |
Family
ID=42310058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98365067T PT2370575T (pt) | 2008-12-17 | 2009-12-17 | Integração dirigida no locus zp15 |
Country Status (18)
Country | Link |
---|---|
US (1) | US8329986B2 (pt) |
EP (1) | EP2370575B1 (pt) |
JP (2) | JP2012511926A (pt) |
KR (1) | KR101683928B1 (pt) |
CN (1) | CN102333868B (pt) |
AR (1) | AR074783A1 (pt) |
AU (1) | AU2009333863B2 (pt) |
BR (1) | BRPI0922641B1 (pt) |
CA (1) | CA2747124C (pt) |
DK (1) | DK2370575T3 (pt) |
ES (1) | ES2654923T3 (pt) |
HR (1) | HRP20180074T1 (pt) |
HU (1) | HUE037911T2 (pt) |
IL (1) | IL213557A (pt) |
PT (1) | PT2370575T (pt) |
SI (1) | SI2370575T1 (pt) |
WO (1) | WO2010077319A1 (pt) |
ZA (1) | ZA201104014B (pt) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2755192C (en) | 2009-03-20 | 2018-09-11 | Sangamo Biosciences, Inc. | Modification of cxcr4 using engineered zinc finger proteins |
CA3038144C (en) | 2009-08-19 | 2023-03-14 | Yunxing Cory Cui | Aad-1 event das-40278-9, related transgenic corn lines, and event-specific identification thereof |
AU2011207769B2 (en) | 2010-01-22 | 2015-05-28 | Corteva Agriscience Llc | Targeted genomic alteration |
MX2013010911A (es) * | 2011-03-23 | 2015-03-03 | Pioneer Hi Bred Int | Metodos para producir un locus de rasgo transgenico complejo. |
EP2771457B1 (en) | 2011-10-27 | 2017-11-22 | Sangamo Therapeutics, Inc. | Methods and compositions for modification of the hprt locus |
AP2014007886A0 (en) * | 2012-02-01 | 2014-08-31 | Dow Agrosciences Llc | Synthetic chloroplast transit peptides |
US11518997B2 (en) | 2012-04-23 | 2022-12-06 | BASF Agricultural Solutions Seed US LLC | Targeted genome engineering in plants |
MX344903B (es) | 2012-05-02 | 2017-01-11 | Dow Agrosciences Llc | Modificación dirigida de deshidrogenasa de malato. |
WO2013169802A1 (en) | 2012-05-07 | 2013-11-14 | Sangamo Biosciences, Inc. | Methods and compositions for nuclease-mediated targeted integration of transgenes |
US10648001B2 (en) | 2012-07-11 | 2020-05-12 | Sangamo Therapeutics, Inc. | Method of treating mucopolysaccharidosis type I or II |
BR112015004995B1 (pt) | 2012-09-07 | 2023-05-02 | Sangamo Biosciences, Inc. | Método para modificação do genoma de uma célula, uso de uma célula, semente ou planta obtida pelo referido método e nuclease de dedo de zinco sítio específica |
UA118090C2 (uk) | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
KR20150085846A (ko) * | 2012-11-20 | 2015-07-24 | 제이.알.심프롯캄패니 | Tal-매개 전이 DNA 삽입방법 |
CA2895117A1 (en) * | 2012-12-13 | 2014-06-19 | James W. Bing | Precision gene targeting to a particular locus in maize |
RU2723130C2 (ru) | 2013-04-05 | 2020-06-08 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы и композиции для встраивания экзогенной последовательности в геном растений |
CA2910427C (en) | 2013-05-10 | 2024-02-20 | Sangamo Biosciences, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering |
WO2014186585A2 (en) * | 2013-05-15 | 2014-11-20 | Sangamo Biosciences, Inc. | Methods and compositions for treatment of a genetic condition |
CN105829536A (zh) | 2013-08-22 | 2016-08-03 | 纳幕尔杜邦公司 | 用于在不掺入选择性转基因标记的情况下,在植物基因组中产生基因修饰的方法,以及用于这种方法的组合物 |
JP6588438B2 (ja) | 2013-08-28 | 2019-10-09 | サンガモ セラピューティクス, インコーポレイテッド | Dna結合ドメインと切断ドメインとを連結するための組成物 |
KR20150026336A (ko) * | 2013-09-02 | 2015-03-11 | 엘지전자 주식회사 | 웨어러블 디바이스 및 그 컨텐트 출력 방법 |
CA2922823C (en) | 2013-09-04 | 2023-01-17 | Dow Agrosciences Llc | Rapid targeting analysis in crops for determining donor insertion |
US10117899B2 (en) | 2013-10-17 | 2018-11-06 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells |
US9957526B2 (en) | 2013-10-17 | 2018-05-01 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering |
US10273493B2 (en) | 2013-11-04 | 2019-04-30 | Dow Agrosciences Llc | Optimal maize loci |
US10077449B2 (en) * | 2013-11-04 | 2018-09-18 | Dow Agrosciences Llc | Universal donor system for gene targeting |
NZ719494A (en) | 2013-11-04 | 2017-09-29 | Dow Agrosciences Llc | Optimal maize loci |
RU2016120636A (ru) | 2013-11-04 | 2017-12-06 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Оптимальные локусы сои |
BR102014027436B1 (pt) | 2013-11-04 | 2022-06-28 | Dow Agrosciences Llc | Molécula de ácido nucleico recombinante, e método para a produção de uma célula vegetal transgênica |
US10774338B2 (en) | 2014-01-16 | 2020-09-15 | The Regents Of The University Of California | Generation of heritable chimeric plant traits |
WO2015116969A2 (en) | 2014-01-30 | 2015-08-06 | The Board Of Trustees Of The University Of Arkansas | Method, vectors, cells, seeds and kits for stacking genes into a single genomic site |
WO2015164748A1 (en) | 2014-04-24 | 2015-10-29 | Sangamo Biosciences, Inc. | Engineered transcription activator like effector (tale) proteins |
WO2015188065A1 (en) | 2014-06-05 | 2015-12-10 | Sangamo Biosciences, Inc. | Methods and compositions for nuclease design |
AU2015288157A1 (en) | 2014-07-11 | 2017-01-19 | E. I. Du Pont De Nemours And Company | Compositions and methods for producing plants resistant to glyphosate herbicide |
WO2016014794A1 (en) | 2014-07-25 | 2016-01-28 | Sangamo Biosciences, Inc. | Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells |
WO2016014837A1 (en) | 2014-07-25 | 2016-01-28 | Sangamo Biosciences, Inc. | Gene editing for hiv gene therapy |
US9616090B2 (en) | 2014-07-30 | 2017-04-11 | Sangamo Biosciences, Inc. | Gene correction of SCID-related genes in hematopoietic stem and progenitor cells |
EP3191595B1 (en) * | 2014-09-12 | 2019-12-25 | E. I. du Pont de Nemours and Company | Generation of site-specific-integration sites for complex trait loci in corn and soybean, and methods of use |
LT3194570T (lt) | 2014-09-16 | 2021-09-27 | Sangamo Therapeutics, Inc. | Būdai ir kompozicijos, skirti kraujodaros kamieninių ląstelių genomo inžinerijai ir korekcijai, kuriai tarpininkauja nukleazė |
CA2969151A1 (en) | 2014-12-23 | 2016-06-30 | Syngenta Participations Ag | Methods and compositions for identifying and enriching for cells comprising site specific genomic modifications |
BR112017017260A2 (pt) | 2015-03-27 | 2018-04-17 | Du Pont | construções de dna, vetor, célula, plantas, semente, método de expressão de rna e método de modificação de local alvo |
AU2016291778B2 (en) | 2015-07-13 | 2021-05-06 | Sangamo Therapeutics, Inc. | Delivery methods and compositions for nuclease-mediated genome engineering |
JP6113310B2 (ja) * | 2016-01-15 | 2017-04-12 | ダウ アグロサイエンシィズ エルエルシー | Aad−1イベントdas−40278−9、関連するトランスジェニックトウモロコシ系統およびそのイベント特異的同定 |
JP7012650B2 (ja) | 2016-02-02 | 2022-01-28 | サンガモ セラピューティクス, インコーポレイテッド | Dna結合ドメインと切断ドメインとを連結するための組成物 |
CA3041668A1 (en) | 2016-10-31 | 2018-05-03 | Sangamo Therapeutics, Inc. | Gene correction of scid-related genes in hematopoietic stem and progenitor cells |
CA3059793A1 (en) | 2017-05-03 | 2018-11-08 | Sangamo Therapeutics, Inc. | Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (cftr) gene |
BR112020008568A2 (pt) | 2017-11-09 | 2020-10-06 | Sangamo Therapeutics, Inc. | modificação genética de gene de proteína contendo sh2 indutível por citoquina (cish) |
JP7332622B2 (ja) | 2018-04-18 | 2023-08-23 | サンガモ セラピューティクス, インコーポレイテッド | ハンチンチン(htt)の調節のためのジンクフィンガータンパク質組成物 |
US11690921B2 (en) | 2018-05-18 | 2023-07-04 | Sangamo Therapeutics, Inc. | Delivery of target specific nucleases |
CN113166744A (zh) | 2018-12-14 | 2021-07-23 | 先锋国际良种公司 | 用于基因组编辑的新颖crispr-cas系统 |
AR125199A1 (es) | 2021-03-23 | 2023-06-21 | Iovance Biotherapeutics Inc | Edición génica cish de linfocitos infiltrantes de tumores y usos de los mismos en inmunoterapia |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5422251A (en) | 1986-11-26 | 1995-06-06 | Princeton University | Triple-stranded nucleic acids |
US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
US5633434A (en) | 1990-02-02 | 1997-05-27 | Hoechst Aktiengesellschaft | Transgenic plants displaying virus and phosphinothricin resistance |
US5420032A (en) * | 1991-12-23 | 1995-05-30 | Universitge Laval | Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence |
US5487994A (en) * | 1992-04-03 | 1996-01-30 | The Johns Hopkins University | Insertion and deletion mutants of FokI restriction endonuclease |
US5356802A (en) | 1992-04-03 | 1994-10-18 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease |
US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
US5792632A (en) * | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
WO1994000977A1 (en) | 1992-07-07 | 1994-01-20 | Japan Tobacco Inc. | Method of transforming monocotyledon |
US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
US6242568B1 (en) * | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
WO1995019431A1 (en) | 1994-01-18 | 1995-07-20 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
US5585245A (en) | 1994-04-22 | 1996-12-17 | California Institute Of Technology | Ubiquitin-based split protein sensor |
JP4118327B2 (ja) | 1994-08-20 | 2008-07-16 | ゲンダック・リミテッド | Dna認識のための結合タンパク質におけるまたはそれに関連する改良 |
GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
US5789538A (en) * | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
US5925523A (en) * | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
GB2338237B (en) | 1997-02-18 | 2001-02-28 | Actinova Ltd | In vitro peptide or protein expression library |
GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
US6342345B1 (en) | 1997-04-02 | 2002-01-29 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of molecular interactions by reporter subunit complementation |
GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AR014491A1 (es) | 1998-01-29 | 2001-02-28 | Dow Agrosciences Llc | Metodo para obtener plantas transgenicas fertiles de gossypium hirsutum. |
US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
DE69942334D1 (de) | 1998-03-02 | 2010-06-17 | Massachusetts Inst Technology | Poly-zinkfinger-proteine mit verbesserten linkern |
US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
US6453242B1 (en) * | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
US7030215B2 (en) * | 1999-03-24 | 2006-04-18 | Sangamo Biosciences, Inc. | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
JP2003512025A (ja) * | 1999-08-05 | 2003-04-02 | アイコン・ジェネティクス,インコーポレイテッド | 植物人工染色体の生産方法 |
WO2001053480A1 (en) | 2000-01-24 | 2001-07-26 | Sangamo Biosciences, Inc. | Nucleic acid binding polypeptides characterized by flexible linkers connected nucleic acid binding modules |
US20020061512A1 (en) | 2000-02-18 | 2002-05-23 | Kim Jin-Soo | Zinc finger domains and methods of identifying same |
US20030044787A1 (en) | 2000-05-16 | 2003-03-06 | Joung J. Keith | Methods and compositions for interaction trap assays |
JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
AU2002241946B2 (en) | 2001-01-22 | 2007-04-26 | Sangamo Therapeutics, Inc. | Modified zinc finger binding proteins |
GB0108491D0 (en) | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
EP1421177A4 (en) | 2001-08-20 | 2006-06-07 | Scripps Research Inst | ZINC FINGER FASTENING DOMAINS FOR CNN |
CA2474486C (en) * | 2002-01-23 | 2013-05-14 | The University Of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
EP2368982A3 (en) * | 2002-03-21 | 2011-10-12 | Sangamo BioSciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
US7179902B2 (en) | 2002-06-27 | 2007-02-20 | Dow Agrosciences Llc | Use of regulatory sequences in transgenic plants |
EP2806025B1 (en) | 2002-09-05 | 2019-04-03 | California Institute of Technology | Use of zinc finger nucleases to stimulate gene targeting |
US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
US20070134796A1 (en) | 2005-07-26 | 2007-06-14 | Sangamo Biosciences, Inc. | Targeted integration and expression of exogenous nucleic acid sequences |
WO2005014791A2 (en) | 2003-08-08 | 2005-02-17 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
US8729341B2 (en) * | 2004-02-23 | 2014-05-20 | University Of Chicago | Plants modified with mini-chromosomes |
EP2298901B2 (en) * | 2004-04-30 | 2017-04-26 | Dow AgroSciences LLC | Novel herbicide resistance genes |
US20080131962A1 (en) | 2006-05-25 | 2008-06-05 | Sangamo Biosciences, Inc. | Engineered cleavage half-domains |
EP2003205B1 (en) * | 2004-12-28 | 2013-05-01 | Pioneer Hi-Bred International, Inc. | Improved grain quality through altered expression of seed proteins |
ES2347684T3 (es) | 2005-03-15 | 2010-11-03 | Cellectis | Variantes de la meganucleasa i-crei con especificidad modifica, metodo de preparacion y usos de las mismas. |
EP2650365B1 (en) * | 2005-10-18 | 2016-09-14 | Precision Biosciences | Rationally designed meganucleases with altered sequence specificity and DNA-binding affinity |
KR100740694B1 (ko) * | 2006-02-09 | 2007-07-18 | 한국생명공학연구원 | 색소체 게놈 내에 삽입된 외래유전자의 이차 재조합을방지하기 위한 벡터개발 |
NZ597995A (en) * | 2006-12-14 | 2013-05-31 | Dow Agrosciences Llc | Optimized non-canonical zinc finger proteins |
WO2008133938A2 (en) * | 2007-04-26 | 2008-11-06 | Sangamo Biosciences, Inc. | Targeted integration into the ppp1r12c locus |
US8278505B2 (en) | 2007-05-09 | 2012-10-02 | Dow Agrosciences, Llc. | Herbicide resistance genes for resistance to aryloxyalkanoate herbicides |
JP2009047247A (ja) | 2007-08-20 | 2009-03-05 | Yamaha Motor Co Ltd | エアクリーナ、無段変速機のケース、エンジンユニット及び鞍乗型車両 |
SI2205749T1 (sl) * | 2007-09-27 | 2016-09-30 | Dow Agrosciences, Llc | Konstruirani proteini s cinkovim prstom, usmerjeni v 5-enolpiruvil-šikimat-3-fosfat-sintazne gene |
CA2700231C (en) | 2007-09-27 | 2018-09-18 | Sangamo Biosciences, Inc. | Rapid in vivo identification of biologically active nucleases |
RU2495935C2 (ru) * | 2007-10-05 | 2013-10-20 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы переноса молекулярных веществ в клетки растений |
EP2281050B1 (en) * | 2008-04-14 | 2014-04-02 | Sangamo BioSciences, Inc. | Linear donor constructs for targeted integration |
-
2009
- 2009-12-17 AU AU2009333863A patent/AU2009333863B2/en active Active
- 2009-12-17 PT PT98365067T patent/PT2370575T/pt unknown
- 2009-12-17 AR ARP090104955A patent/AR074783A1/es unknown
- 2009-12-17 EP EP09836506.7A patent/EP2370575B1/en active Active
- 2009-12-17 WO PCT/US2009/006606 patent/WO2010077319A1/en active Application Filing
- 2009-12-17 SI SI200931795T patent/SI2370575T1/en unknown
- 2009-12-17 CN CN200980156926.7A patent/CN102333868B/zh active Active
- 2009-12-17 BR BRPI0922641-9A patent/BRPI0922641B1/pt active IP Right Grant
- 2009-12-17 CA CA2747124A patent/CA2747124C/en active Active
- 2009-12-17 ES ES09836506.7T patent/ES2654923T3/es active Active
- 2009-12-17 DK DK09836506.7T patent/DK2370575T3/en active
- 2009-12-17 JP JP2011542133A patent/JP2012511926A/ja not_active Withdrawn
- 2009-12-17 US US12/653,735 patent/US8329986B2/en active Active
- 2009-12-17 HU HUE09836506A patent/HUE037911T2/hu unknown
- 2009-12-17 KR KR1020117016519A patent/KR101683928B1/ko active IP Right Grant
-
2011
- 2011-05-31 ZA ZA2011/04014A patent/ZA201104014B/en unknown
- 2011-06-14 IL IL213557A patent/IL213557A/en active IP Right Grant
-
2015
- 2015-07-02 JP JP2015133818A patent/JP6127297B2/ja active Active
-
2018
- 2018-01-16 HR HRP20180074TT patent/HRP20180074T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CA2747124C (en) | 2018-09-04 |
EP2370575A1 (en) | 2011-10-05 |
BRPI0922641A2 (pt) | 2020-10-20 |
SI2370575T1 (en) | 2018-07-31 |
JP6127297B2 (ja) | 2017-05-17 |
CN102333868A (zh) | 2012-01-25 |
CN102333868B (zh) | 2015-01-07 |
HRP20180074T1 (hr) | 2018-04-06 |
JP2012511926A (ja) | 2012-05-31 |
KR20110095420A (ko) | 2011-08-24 |
CA2747124A1 (en) | 2010-07-08 |
EP2370575B1 (en) | 2017-11-01 |
ZA201104014B (en) | 2013-05-29 |
ES2654923T3 (es) | 2018-02-15 |
AR074783A1 (es) | 2011-02-09 |
KR101683928B1 (ko) | 2016-12-07 |
HUE037911T2 (hu) | 2018-09-28 |
JP2015226537A (ja) | 2015-12-17 |
AU2009333863B2 (en) | 2015-02-05 |
US20100199389A1 (en) | 2010-08-05 |
AU2009333863A1 (en) | 2011-07-07 |
IL213557A0 (en) | 2011-07-31 |
IL213557A (en) | 2015-02-26 |
US8329986B2 (en) | 2012-12-11 |
BRPI0922641B1 (pt) | 2021-10-26 |
EP2370575A4 (en) | 2012-05-09 |
WO2010077319A1 (en) | 2010-07-08 |
DK2370575T3 (en) | 2018-02-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL213557A0 (en) | Targeted integration into the zp15 locus | |
GB0812320D0 (en) | Activation | |
GB0702228D0 (en) | The cosy-cushion | |
GB0707146D0 (en) | The bealyboard | |
GB0818787D0 (en) | The permenforce cruth | |
GB0701309D0 (en) | The easi-strutt | |
GB0800503D0 (en) | The cliffie | |
GB0819230D0 (en) | The smartsack-peg | |
GB0820570D0 (en) | The boatglider | |
GB0809244D0 (en) | The saviour | |
GB0808155D0 (en) | The lilolift | |
GB0808006D0 (en) | The bathmate | |
GB0807757D0 (en) | The wellie-checker | |
GB0806847D0 (en) | The karkip | |
GB0806717D0 (en) | The slugdefenda | |
GB0803937D0 (en) | The ouchcouch | |
GB0802514D0 (en) | The sqeasy | |
IL190048A0 (en) | The spoutch | |
GB0800600D0 (en) | the turbomax | |
GB0817587D0 (en) | The milkbox | |
GB0821263D0 (en) | The mini-room | |
GB0822208D0 (en) | The rigmaster | |
GB0823439D0 (en) | The twiddle - filtoid | |
GB0800715D0 (en) | The Smartsack | |
GB0818378D0 (en) | The yazee |