PT2346874E - Processo para preparação de clorinas e seus usos farmaceuticos - Google Patents
Processo para preparação de clorinas e seus usos farmaceuticos Download PDFInfo
- Publication number
- PT2346874E PT2346874E PT97682553T PT09768255T PT2346874E PT 2346874 E PT2346874 E PT 2346874E PT 97682553 T PT97682553 T PT 97682553T PT 09768255 T PT09768255 T PT 09768255T PT 2346874 E PT2346874 E PT 2346874E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical uses
- chlorins
- preparing
- preparing chlorins
- pharmaceutical
- Prior art date
Links
- 150000004035 chlorins Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0819594.3A GB0819594D0 (en) | 2008-10-24 | 2008-10-24 | Process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2346874E true PT2346874E (pt) | 2014-03-06 |
Family
ID=40133817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97682553T PT2346874E (pt) | 2008-10-24 | 2009-10-22 | Processo para preparação de clorinas e seus usos farmaceuticos |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9670217B2 (OSRAM) |
| EP (1) | EP2346874B1 (OSRAM) |
| JP (1) | JP5567024B2 (OSRAM) |
| CN (1) | CN102227432B (OSRAM) |
| AU (1) | AU2009307106B2 (OSRAM) |
| BR (1) | BRPI0919868B8 (OSRAM) |
| CA (1) | CA2741429C (OSRAM) |
| DK (1) | DK2346874T3 (OSRAM) |
| ES (1) | ES2450136T3 (OSRAM) |
| GB (1) | GB0819594D0 (OSRAM) |
| PL (1) | PL2346874T3 (OSRAM) |
| PT (1) | PT2346874E (OSRAM) |
| RU (1) | RU2513483C2 (OSRAM) |
| WO (1) | WO2010047611A1 (OSRAM) |
| ZA (1) | ZA201102760B (OSRAM) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8524239B2 (en) | 2010-07-09 | 2013-09-03 | The United States of America as represented by the Secrectary, Department of Health and Human Services | Photosensitizing antibody-fluorophore conjugates |
| JP6127045B2 (ja) * | 2011-07-11 | 2017-05-10 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 光増感抗体−蛍光団コンジュゲート |
| US9371555B2 (en) | 2012-06-01 | 2016-06-21 | Concordia Laboratories Inc. | Lighting systems and methods of using lighting systems for in vitro potency assay for photofrin |
| CN103721257B (zh) * | 2012-10-16 | 2016-12-21 | 无锡兆真辐射技术有限公司 | 光敏素催化分解过氧化氢系列药物 |
| GB201221125D0 (en) | 2012-11-23 | 2013-01-09 | Morex Dev Partners Llp | Pharmaceutial formulations |
| WO2014110149A2 (en) * | 2013-01-08 | 2014-07-17 | Stoneburner Jon F | Method of testing or treating the presence of live viruses |
| CN111388672A (zh) | 2014-08-08 | 2020-07-10 | 美国政府(由卫生和人类服务部的部长所代表) | 在体内和在体外的靶标的光控移除 |
| CN107427580B (zh) * | 2015-03-20 | 2020-11-17 | 卢西蒂恩股份有限公司 | 卤代四苯基细菌卟吩和二氢卟吩的阻转异构体及它们在光动力学疗法中的应用 |
| HK1245254A1 (zh) * | 2015-05-07 | 2018-08-24 | 卢西蒂恩股份有限公司 | 甲酰胺卤化的卟啉的低分子量衍生物、即二氢卟酚和菌绿素及其应用 |
| WO2017027247A1 (en) | 2015-08-07 | 2017-02-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Near infrared photoimmunotherapy (nir-pit) of suppressor cells to treat cancer |
| CN119564879A (zh) | 2015-08-18 | 2025-03-07 | 乐天医药生技股份有限公司 | 用于光免疫疗法的组合物、联用及相关方法 |
| AU2016308286B2 (en) | 2015-08-18 | 2022-04-07 | Rakuten Medical, Inc. | Phthalocyanine dye conjugates and their storage |
| WO2017051435A1 (en) * | 2015-09-22 | 2017-03-30 | Council Of Scientific And Industrial Research | Chlorin based compounds, a process for preparation thereof and use as photodynamic therapeutic agents and fluorescent probes |
| US10744212B2 (en) | 2016-03-14 | 2020-08-18 | General Electric Company | Topical application of nerve labeling dyes for image-guided surgery |
| WO2018065384A1 (en) * | 2016-10-03 | 2018-04-12 | Galderma Research & Development | Expression profiles of abc and slc transporters in human and minipig skin, liver and kidney |
| WO2018216679A1 (ja) * | 2017-05-22 | 2018-11-29 | 国立大学法人京都大学 | テトラフェニルポルフィリン誘導体 |
| WO2019067523A1 (en) * | 2017-09-29 | 2019-04-04 | Duke University | FLUOROSUBSTITUTED PORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF PREPARATION AND USE THEREOF |
| AU2019276572B2 (en) | 2018-06-01 | 2024-11-21 | Rakuten Medical, Inc. | Phthalocyanine dye conjugate compositions |
| CN109912607B (zh) * | 2018-12-11 | 2021-01-22 | 南华大学 | 一类卟啉-白杨素复合物及其抗肿瘤活性 |
| CN109651383B (zh) * | 2019-01-25 | 2021-11-16 | 华东理工大学 | 用于光敏剂的化合物及其应用 |
| JP7754724B2 (ja) * | 2019-05-20 | 2025-10-15 | ニルバナ サイエンシーズ インク. | 発光波長の範囲が狭い発光染料、それを含む組成物及びそれを製造及び使用する方法 |
| RU2725876C1 (ru) * | 2019-07-15 | 2020-07-07 | Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) | Производные фторсодержащих хлоринов, проявляющие противоопухолевую активность |
| CN114504551B (zh) * | 2020-11-16 | 2024-01-02 | 北京厚燊维康科技有限责任公司 | 可用于光动力治疗或诊断的制剂 |
| RU2759743C2 (ru) * | 2021-04-14 | 2021-11-17 | Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения Российской Федерации (ФГБУ «НМИЦ радиологии» Минздрава России) | Способ комбинированного лечения локализованного t1-t2n0m0 рака гортани |
| JPWO2023022187A1 (OSRAM) * | 2021-08-18 | 2023-02-23 | ||
| MY208934A (en) * | 2021-10-06 | 2025-06-12 | Tunku Abdul Rahman Univ Of Management And Technology Tar Umt | Treating skin diseases using a photodynamic therapy (pdt) and a topical agent photosensitizer formulation |
| CN114813592A (zh) * | 2022-03-11 | 2022-07-29 | 华南理工大学 | 一种探究羟基氯喹在自然水体中降解机理的方法 |
| CN114870011B (zh) * | 2022-03-24 | 2023-06-06 | 深圳大学 | 一种增强实体瘤内原卟啉ix蓄积的微针贴片及其制备方法 |
| CN119751254B (zh) * | 2025-01-13 | 2025-11-28 | 浙江工业大学 | 一种光催化氧化甲烷制备三氟乙酸甲酯的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405616A (en) | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
| US3989816A (en) | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
| US4562075A (en) | 1982-05-20 | 1985-12-31 | Nelson Research & Development Co. | Penetration enhancers for transdermal drug delivery of systemic agents |
| US4218803A (en) | 1979-05-25 | 1980-08-26 | Clifford Jack R | Implement for cleaning tubular culverts |
| US5171741A (en) | 1989-04-21 | 1992-12-15 | Health Research, Inc. | Bacteriochlorophyll-a derivatives useful in photodynamic therapy |
| US5079262A (en) | 1989-07-28 | 1992-01-07 | Queen's University At Kingston | Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid |
| CA2138538A1 (en) | 1992-06-19 | 1994-01-06 | Dimitris Skalkos | Production and use of imines of porphyrins |
| US5591847A (en) | 1994-05-23 | 1997-01-07 | Health Research, Inc. | Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages |
| RU2071320C1 (ru) * | 1994-09-29 | 1997-01-10 | Акционерное общество закрытого типа Научно-производственное предприятие "Мелодит" | Сенсибилизатор для фотодинамического разрушения клеток злокачественных новообразований |
| US5648485A (en) | 1994-10-26 | 1997-07-15 | University Of British Columbia | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
| US5770730A (en) | 1996-03-08 | 1998-06-23 | Health Research, Inc. | Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer |
| JP2000007693A (ja) * | 1998-06-26 | 2000-01-11 | Lederle Japan Ltd | クロリン誘導体 |
| CA2353554C (en) | 1998-12-09 | 2011-04-26 | Yeda Research And Development Co. Ltd. | Palladium-substituted bacteriochlorophyll derivatives and use thereof |
| US6376483B1 (en) | 1999-05-27 | 2002-04-23 | Miravant Pharmaceuticals, Inc. | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
| US6624187B1 (en) | 2000-06-12 | 2003-09-23 | Health Research, Inc. | Long wave length absorbing bacteriochlorin alkyl ether analogs |
| GB0121023D0 (en) * | 2001-08-30 | 2001-10-24 | Norwegian Radium Hospital Res | Compound |
| PT102721B (pt) * | 2002-02-01 | 2011-01-24 | Cipan Companhia Industr Prod De Antibioticos S A | Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação |
| CA2490692A1 (en) | 2002-06-27 | 2004-01-08 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
| FR2877943B1 (fr) * | 2004-11-16 | 2008-09-05 | Univ De Coimbra | Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique |
| US7534807B2 (en) | 2005-02-18 | 2009-05-19 | North Carolina State University | De novo synthesis of bacteriochlorins |
| EP2123664A1 (en) * | 2007-02-19 | 2009-11-25 | Rei Medical Co., Ltd. | Novel sugar-linked chlorin derivative and process for production thereof |
-
2008
- 2008-10-24 GB GBGB0819594.3A patent/GB0819594D0/en not_active Ceased
-
2009
- 2009-10-22 EP EP09768255.3A patent/EP2346874B1/en not_active Not-in-force
- 2009-10-22 CN CN200980147426.7A patent/CN102227432B/zh not_active Expired - Fee Related
- 2009-10-22 US US13/125,805 patent/US9670217B2/en not_active Expired - Fee Related
- 2009-10-22 WO PCT/PT2009/000057 patent/WO2010047611A1/en not_active Ceased
- 2009-10-22 DK DK09768255.3T patent/DK2346874T3/en active
- 2009-10-22 RU RU2011114878/04A patent/RU2513483C2/ru active
- 2009-10-22 PT PT97682553T patent/PT2346874E/pt unknown
- 2009-10-22 ES ES09768255.3T patent/ES2450136T3/es active Active
- 2009-10-22 JP JP2011533133A patent/JP5567024B2/ja not_active Expired - Fee Related
- 2009-10-22 CA CA2741429A patent/CA2741429C/en active Active
- 2009-10-22 BR BRPI0919868A patent/BRPI0919868B8/pt not_active IP Right Cessation
- 2009-10-22 AU AU2009307106A patent/AU2009307106B2/en not_active Ceased
- 2009-10-22 PL PL09768255T patent/PL2346874T3/pl unknown
-
2011
- 2011-04-13 ZA ZA2011/02760A patent/ZA201102760B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010047611A1 (en) | 2010-04-29 |
| EP2346874A1 (en) | 2011-07-27 |
| ZA201102760B (en) | 2012-07-25 |
| JP2012506425A (ja) | 2012-03-15 |
| RU2011114878A (ru) | 2012-11-27 |
| BRPI0919868B8 (pt) | 2021-05-25 |
| ES2450136T3 (es) | 2014-03-24 |
| AU2009307106A1 (en) | 2010-04-29 |
| CA2741429A1 (en) | 2011-04-29 |
| DK2346874T3 (en) | 2014-03-03 |
| GB0819594D0 (en) | 2008-12-03 |
| CA2741429C (en) | 2017-04-18 |
| JP5567024B2 (ja) | 2014-08-06 |
| BRPI0919868B1 (pt) | 2020-10-27 |
| RU2513483C2 (ru) | 2014-04-20 |
| BRPI0919868A2 (pt) | 2015-12-15 |
| AU2009307106B2 (en) | 2015-05-07 |
| PL2346874T3 (pl) | 2014-05-30 |
| WO2010047611A9 (en) | 2010-07-22 |
| CN102227432A (zh) | 2011-10-26 |
| EP2346874B1 (en) | 2013-12-04 |
| US20110250143A1 (en) | 2011-10-13 |
| CN102227432B (zh) | 2015-04-22 |
| US9670217B2 (en) | 2017-06-06 |
| HK1160848A1 (en) | 2012-08-17 |
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