HK1245254A1 - 甲酰胺鹵化的卟啉的低分子量衍生物、即二氫卟酚和菌綠素及其應用 - Google Patents

甲酰胺鹵化的卟啉的低分子量衍生物、即二氫卟酚和菌綠素及其應用

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Publication number
HK1245254A1
HK1245254A1 HK18104533.6A HK18104533A HK1245254A1 HK 1245254 A1 HK1245254 A1 HK 1245254A1 HK 18104533 A HK18104533 A HK 18104533A HK 1245254 A1 HK1245254 A1 HK 1245254A1
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HK
Hong Kong
Prior art keywords
bacteriochlorins
chlorins
namely
applications
molecular weight
Prior art date
Application number
HK18104533.6A
Other languages
English (en)
Inventor
‧佩雷拉 納西門托 科斯塔 G
貢薩爾維斯 N‧P‧佩雷拉
蒙泰羅 C‧J‧佩雷拉
德 阿布雷烏 A‧C‧雷斯
卡多佐 蘇亞雷斯 H‧T‧費拉斯
羅沙 L‧G‧博爾熱斯
F‧A‧沙伯勒
佩雷拉 M‧米根斯
席爾瓦 阿爾瑙特 莫雷拉 L‧G‧達
Original Assignee
盧西蒂恩股份有限公司
科英布拉大學
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 盧西蒂恩股份有限公司, 科英布拉大學 filed Critical 盧西蒂恩股份有限公司
Publication of HK1245254A1 publication Critical patent/HK1245254A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
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    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
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    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
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    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Dermatology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18104533.6A 2015-05-07 2018-04-06 甲酰胺鹵化的卟啉的低分子量衍生物、即二氫卟酚和菌綠素及其應用 HK1245254A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT10844715 2015-05-07
PCT/IB2016/052606 WO2016178191A1 (en) 2015-05-07 2016-05-06 Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof

Publications (1)

Publication Number Publication Date
HK1245254A1 true HK1245254A1 (zh) 2018-08-24

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ID=56084187

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HK18104533.6A HK1245254A1 (zh) 2015-05-07 2018-04-06 甲酰胺鹵化的卟啉的低分子量衍生物、即二氫卟酚和菌綠素及其應用

Country Status (11)

Country Link
US (1) US10450322B2 (zh)
EP (1) EP3292129B1 (zh)
JP (1) JP6730319B2 (zh)
CN (1) CN107624114B (zh)
AU (1) AU2016259188B2 (zh)
BR (1) BR112017023948A2 (zh)
CA (1) CA2985187C (zh)
HK (1) HK1245254A1 (zh)
RU (1) RU2718923C2 (zh)
WO (1) WO2016178191A1 (zh)
ZA (1) ZA201707533B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11904026B2 (en) 2017-02-03 2024-02-20 Nirvana Sciences Inc. Metallohydroporphyrins for photoacoustic imaging
US20200009272A1 (en) * 2017-02-03 2020-01-09 Nirvana Sciences Inc. Hydroporphyrins for photoacoustic imaging
CN109912607B (zh) * 2018-12-11 2021-01-22 南华大学 一类卟啉-白杨素复合物及其抗肿瘤活性
SG10201811547RA (en) * 2018-12-21 2020-07-29 Oreal Cosmetic use of a short chain fatty acid (scfa) for preventing and/or treating dry skin and/or aged skin
CN109651383B (zh) * 2019-01-25 2021-11-16 华东理工大学 用于光敏剂的化合物及其应用
CA3138406A1 (en) * 2019-05-20 2020-11-26 Christopher J. MACNEVIN Narrow emission dyes, compositions comprising same, and methods for making and using same
CN116354970A (zh) * 2023-03-28 2023-06-30 大连理工大学 一种卟啉类一氧化碳前药的制备方法及气体-声动力联合治疗应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
JP2013503895A (ja) * 2009-09-02 2013-02-04 ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド，ア ボディー コーポレート 金属ポルフィリン類を使用するミトコンドリア病の処置法
WO2011099602A1 (ja) 2010-02-12 2011-08-18 学校法人日本大学 ポルフィリン誘導体および放射線力学療法におけるその使用
CN102166182A (zh) * 2011-01-24 2011-08-31 上海交通大学 纳米探针及其在肿瘤诊断组合物和光动力疗法中的应用
WO2016051361A1 (en) 2014-09-30 2016-04-07 Biolitec Unternehmensbeteiligungs Ii Ag Specifically meso-substituted porphyrins and chlorins for photodynamic therapy

Also Published As

Publication number Publication date
BR112017023948A2 (pt) 2018-07-24
EP3292129A1 (en) 2018-03-14
US20180282344A1 (en) 2018-10-04
CN107624114A (zh) 2018-01-23
JP6730319B2 (ja) 2020-07-29
RU2017138871A3 (zh) 2019-06-11
AU2016259188A1 (en) 2017-11-30
RU2718923C2 (ru) 2020-04-15
EP3292129B1 (en) 2019-03-27
CN107624114B (zh) 2021-03-23
CA2985187C (en) 2024-01-02
AU2016259188B2 (en) 2019-10-31
WO2016178191A1 (en) 2016-11-10
CA2985187A1 (en) 2016-11-10
JP2018515498A (ja) 2018-06-14
US10450322B2 (en) 2019-10-22
RU2017138871A (ru) 2019-06-10
ZA201707533B (en) 2019-04-24

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