PT2173730E - Novos compostos 951: um ácido bifeniloxipropanóico como modulador de crth2 e intermediários - Google Patents

Novos compostos 951: um ácido bifeniloxipropanóico como modulador de crth2 e intermediários Download PDF

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Publication number
PT2173730E
PT2173730E PT87761649T PT08776164T PT2173730E PT 2173730 E PT2173730 E PT 2173730E PT 87761649 T PT87761649 T PT 87761649T PT 08776164 T PT08776164 T PT 08776164T PT 2173730 E PT2173730 E PT 2173730E
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Prior art keywords
biphenyloxypropanoic
intermediates
acid
novel compounds
crth2
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PT87761649T
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English (en)
Inventor
Roger Victor Bonnert
Timothy Jon Luker
Anil Patel
Aaron Rigby
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Astrazeneca Ab
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Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT2173730E publication Critical patent/PT2173730E/pt

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
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    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
PT87761649T 2007-07-05 2008-07-01 Novos compostos 951: um ácido bifeniloxipropanóico como modulador de crth2 e intermediários PT2173730E (pt)

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US94801207P 2007-07-05 2007-07-05

Publications (1)

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PT2173730E true PT2173730E (pt) 2014-01-16

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ID=39942682

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PT87761649T PT2173730E (pt) 2007-07-05 2008-07-01 Novos compostos 951: um ácido bifeniloxipropanóico como modulador de crth2 e intermediários

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US (1) US8507544B2 (pt)
EP (1) EP2173730B1 (pt)
JP (1) JP5368438B2 (pt)
KR (1) KR20100039326A (pt)
CN (1) CN101796042B (pt)
AR (1) AR067461A1 (pt)
AU (1) AU2008272690B2 (pt)
BR (1) BRPI0813992A2 (pt)
CA (1) CA2691615A1 (pt)
CL (1) CL2008001982A1 (pt)
CO (1) CO6270211A2 (pt)
CY (1) CY1114804T1 (pt)
DK (1) DK2173730T3 (pt)
EC (1) ECSP109848A (pt)
ES (1) ES2442523T3 (pt)
HK (1) HK1143140A1 (pt)
HR (1) HRP20140004T1 (pt)
MY (1) MY153957A (pt)
NZ (1) NZ582192A (pt)
PE (2) PE20121515A1 (pt)
PL (1) PL2173730T3 (pt)
PT (1) PT2173730E (pt)
RS (1) RS53129B (pt)
SA (1) SA08290406B1 (pt)
SI (1) SI2173730T1 (pt)
TW (1) TWI453017B (pt)
UA (1) UA100983C2 (pt)
UY (1) UY31208A1 (pt)
WO (1) WO2009004379A1 (pt)
ZA (1) ZA200909226B (pt)

Families Citing this family (28)

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SE0301010D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0301009D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0415320D0 (en) * 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) * 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
ATE517085T1 (de) 2004-11-23 2011-08-15 Astrazeneca Ab Zur behandlung von atemwegserkrankungen geeignete phenoxyessigsäurederivate
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
WO2007039736A1 (en) 2005-10-06 2007-04-12 Astrazeneca Ab Novel compounds
US20080255150A1 (en) * 2005-11-05 2008-10-16 Astrazeneca Ab Novel Compounds
EP2305640A3 (en) * 2005-12-15 2011-07-20 AstraZeneca AB Substituted diphenyl-ethers, -amines, -sulfides and -methanes for the treatment of respiratory diseases
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
ES2566739T3 (es) 2008-02-01 2016-04-15 Brickell Biotech, Inc. Aminoalquilbifenilo N,N-disustituidos antagonistas de receptores de prostaglandina D2
EP2245022A4 (en) 2008-02-25 2012-02-22 Panmira Pharmaceuticals Llc ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS
GB2463788B (en) 2008-09-29 2010-12-15 Amira Pharmaceuticals Inc Heteroaryl antagonists of prostaglandin D2 receptors
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WO2010042652A2 (en) 2008-10-08 2010-04-15 Amira Pharmaceuticals, Inc. Heteroalkyl biphenyl antagonists of prostaglandin d2 receptors
GB2465062B (en) 2008-11-06 2011-04-13 Amira Pharmaceuticals Inc Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors
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RS53129B (en) 2014-06-30
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