PT1853241E - Utilização de 2-(2-nitro-4-trifluorometilbenzoil)-1,3- ciclohexanodiona no tratamento de doença de parkinson - Google Patents

Utilização de 2-(2-nitro-4-trifluorometilbenzoil)-1,3- ciclohexanodiona no tratamento de doença de parkinson Download PDF

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Publication number
PT1853241E
PT1853241E PT06709910T PT06709910T PT1853241E PT 1853241 E PT1853241 E PT 1853241E PT 06709910 T PT06709910 T PT 06709910T PT 06709910 T PT06709910 T PT 06709910T PT 1853241 E PT1853241 E PT 1853241E
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PT
Portugal
Prior art keywords
compound
effective amount
pharmaceutically acceptable
alkyl
pharmaceutically effective
Prior art date
Application number
PT06709910T
Other languages
English (en)
Portuguese (pt)
Inventor
John Ernest Doe
Nicholas Crispinian Sturgess
Kim Zachary Travis
Original Assignee
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Ltd filed Critical Syngenta Ltd
Publication of PT1853241E publication Critical patent/PT1853241E/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
PT06709910T 2005-02-28 2006-02-27 Utilização de 2-(2-nitro-4-trifluorometilbenzoil)-1,3- ciclohexanodiona no tratamento de doença de parkinson PT1853241E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0504103.3A GB0504103D0 (en) 2005-02-28 2005-02-28 Novel method

Publications (1)

Publication Number Publication Date
PT1853241E true PT1853241E (pt) 2012-01-11

Family

ID=34430351

Family Applications (1)

Application Number Title Priority Date Filing Date
PT06709910T PT1853241E (pt) 2005-02-28 2006-02-27 Utilização de 2-(2-nitro-4-trifluorometilbenzoil)-1,3- ciclohexanodiona no tratamento de doença de parkinson

Country Status (17)

Country Link
US (1) US20090326072A1 (enExample)
EP (1) EP1853241B1 (enExample)
JP (1) JP2008531665A (enExample)
CN (1) CN101163466B (enExample)
AT (1) ATE524171T1 (enExample)
AU (1) AU2006217650B2 (enExample)
BR (1) BRPI0609177A2 (enExample)
CA (1) CA2598517A1 (enExample)
DK (1) DK1853241T3 (enExample)
ES (1) ES2374761T3 (enExample)
GB (1) GB0504103D0 (enExample)
IL (1) IL185410A0 (enExample)
MX (1) MX2007010480A (enExample)
PT (1) PT1853241E (enExample)
RU (1) RU2420272C2 (enExample)
WO (1) WO2006090177A1 (enExample)
ZA (1) ZA200707486B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3311813B1 (en) 2007-08-27 2019-08-07 Dart Neuroscience (Cayman) Ltd Therapeutic isoxazole compounds
JP2011507910A (ja) * 2007-12-21 2011-03-10 ユニバーシティー オブ ロチェスター 真核生物の寿命を変更するための方法
US20100160295A1 (en) * 2008-11-06 2010-06-24 Synosia Therapeutics Treatment of restless leg syndrome and sleep disorders
PL2723320T3 (pl) * 2011-06-23 2016-06-30 Swedish Orphan Biovitrum Int Ab Ciekła kompozycja farmaceutyczna zawierająca nityzynon
CN103622942A (zh) * 2013-11-04 2014-03-12 江苏大学 左旋多巴/卡比多巴复方缓释混悬剂及其制备方法
MA42519A (fr) * 2015-07-29 2018-06-06 Takeda Gmbh Inhibiteur de la pde4 pour le traitement de la néphropathie diabétique
ITUB20160650A1 (it) 2016-02-11 2017-08-11 Dipharma S A Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione
US9783485B1 (en) 2016-11-30 2017-10-10 Dipharma S.A. Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780127A (en) * 1982-03-25 1988-10-25 Stauffer Chemical Company Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides
US5092919A (en) * 1991-01-15 1992-03-03 Imperial Chemical Industries Plc Certain 2-(2'-methyl-3',4'-trisubstituted benzoyl)-1,3-cyclohexanediones
DK0591275T3 (da) * 1991-06-24 1999-10-11 Zeneca Ltd Anvendelse af 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyklohexandion til behandling af tyrosinæmi samt farmaceutiske sammen
FR2777781B1 (fr) * 1998-04-24 2004-04-09 Rhone Poulenc Rorer Sa Associations riluzole et l-dopa pour le traitement de la maladie de parkinson
US20050288187A1 (en) * 2002-07-03 2005-12-29 Hanauske-Abel Hartmut M Inhibitor development for 4-hydroxyphenylpyruvate dioxygenase, employing tyrosinemia 1 as a model for human diseases mediated by 2-oxoacid utilizing dioxygenases
EP1646377A4 (en) * 2003-07-11 2009-09-09 Merck & Co Inc TREATMENT OF MOVEMENT DISORDERS WITH METABOTROPIC GLUTAMATE 4 RECEPTOR POSITIVE ALLOSTERIC MODULATOR
AU2006347397A1 (en) * 2006-08-18 2008-02-21 Syngenta Limited Use of HPPD inhibitors in the treatment of depression and/or withdrawal symptoms associated with addictive drugs
US20100160295A1 (en) * 2008-11-06 2010-06-24 Synosia Therapeutics Treatment of restless leg syndrome and sleep disorders

Also Published As

Publication number Publication date
BRPI0609177A2 (pt) 2010-02-23
ES2374761T3 (es) 2012-02-21
AU2006217650A1 (en) 2006-08-31
IL185410A0 (en) 2008-08-07
MX2007010480A (es) 2008-02-07
EP1853241B1 (en) 2011-09-14
AU2006217650B2 (en) 2011-06-09
CA2598517A1 (en) 2006-08-31
RU2420272C2 (ru) 2011-06-10
CN101163466A (zh) 2008-04-16
CN101163466B (zh) 2011-12-07
EP1853241A1 (en) 2007-11-14
JP2008531665A (ja) 2008-08-14
ZA200707486B (en) 2009-02-25
WO2006090177A1 (en) 2006-08-31
US20090326072A1 (en) 2009-12-31
DK1853241T3 (da) 2012-01-16
GB0504103D0 (en) 2005-04-06
HK1110211A1 (en) 2008-07-11
RU2007131934A (ru) 2009-02-27
ATE524171T1 (de) 2011-09-15

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