ATE524171T1 - Verwendung von 2-(2-nitro-4- trifluormethylbenzoyl)-1,3-cyclohexandion bei der behandlung der parkinson-krankheit - Google Patents
Verwendung von 2-(2-nitro-4- trifluormethylbenzoyl)-1,3-cyclohexandion bei der behandlung der parkinson-krankheitInfo
- Publication number
- ATE524171T1 ATE524171T1 AT06709910T AT06709910T ATE524171T1 AT E524171 T1 ATE524171 T1 AT E524171T1 AT 06709910 T AT06709910 T AT 06709910T AT 06709910 T AT06709910 T AT 06709910T AT E524171 T1 ATE524171 T1 AT E524171T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- parkinson
- treatment
- nitro
- trifluormethylbenzoyl
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title abstract 3
- OUBCNLGXQFSTLU-UHFFFAOYSA-N nitisinone Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=CC=C1C(=O)C1C(=O)CCCC1=O OUBCNLGXQFSTLU-UHFFFAOYSA-N 0.000 title abstract 2
- 229940125782 compound 2 Drugs 0.000 abstract 2
- 230000004770 neurodegeneration Effects 0.000 abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0504103.3A GB0504103D0 (en) | 2005-02-28 | 2005-02-28 | Novel method |
| PCT/GB2006/000684 WO2006090177A1 (en) | 2005-02-28 | 2006-02-27 | USE OF 2-(2-NITRO-4-TRIFLUOROMETHYLBENZOYL)-l,3- CYCLOHEXANEDIONE IN THE TREATMENT OF PARKINSON'S DISEASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE524171T1 true ATE524171T1 (de) | 2011-09-15 |
Family
ID=34430351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06709910T ATE524171T1 (de) | 2005-02-28 | 2006-02-27 | Verwendung von 2-(2-nitro-4- trifluormethylbenzoyl)-1,3-cyclohexandion bei der behandlung der parkinson-krankheit |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090326072A1 (enExample) |
| EP (1) | EP1853241B1 (enExample) |
| JP (1) | JP2008531665A (enExample) |
| CN (1) | CN101163466B (enExample) |
| AT (1) | ATE524171T1 (enExample) |
| AU (1) | AU2006217650B2 (enExample) |
| BR (1) | BRPI0609177A2 (enExample) |
| CA (1) | CA2598517A1 (enExample) |
| DK (1) | DK1853241T3 (enExample) |
| ES (1) | ES2374761T3 (enExample) |
| GB (1) | GB0504103D0 (enExample) |
| IL (1) | IL185410A0 (enExample) |
| MX (1) | MX2007010480A (enExample) |
| PT (1) | PT1853241E (enExample) |
| RU (1) | RU2420272C2 (enExample) |
| WO (1) | WO2006090177A1 (enExample) |
| ZA (1) | ZA200707486B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3311813B1 (en) | 2007-08-27 | 2019-08-07 | Dart Neuroscience (Cayman) Ltd | Therapeutic isoxazole compounds |
| JP2011507910A (ja) * | 2007-12-21 | 2011-03-10 | ユニバーシティー オブ ロチェスター | 真核生物の寿命を変更するための方法 |
| US20100160295A1 (en) * | 2008-11-06 | 2010-06-24 | Synosia Therapeutics | Treatment of restless leg syndrome and sleep disorders |
| PL2723320T3 (pl) * | 2011-06-23 | 2016-06-30 | Swedish Orphan Biovitrum Int Ab | Ciekła kompozycja farmaceutyczna zawierająca nityzynon |
| CN103622942A (zh) * | 2013-11-04 | 2014-03-12 | 江苏大学 | 左旋多巴/卡比多巴复方缓释混悬剂及其制备方法 |
| MA42519A (fr) * | 2015-07-29 | 2018-06-06 | Takeda Gmbh | Inhibiteur de la pde4 pour le traitement de la néphropathie diabétique |
| ITUB20160650A1 (it) | 2016-02-11 | 2017-08-11 | Dipharma S A | Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione |
| US9783485B1 (en) | 2016-11-30 | 2017-10-10 | Dipharma S.A. | Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4780127A (en) * | 1982-03-25 | 1988-10-25 | Stauffer Chemical Company | Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides |
| US5092919A (en) * | 1991-01-15 | 1992-03-03 | Imperial Chemical Industries Plc | Certain 2-(2'-methyl-3',4'-trisubstituted benzoyl)-1,3-cyclohexanediones |
| DK0591275T3 (da) * | 1991-06-24 | 1999-10-11 | Zeneca Ltd | Anvendelse af 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyklohexandion til behandling af tyrosinæmi samt farmaceutiske sammen |
| FR2777781B1 (fr) * | 1998-04-24 | 2004-04-09 | Rhone Poulenc Rorer Sa | Associations riluzole et l-dopa pour le traitement de la maladie de parkinson |
| US20050288187A1 (en) * | 2002-07-03 | 2005-12-29 | Hanauske-Abel Hartmut M | Inhibitor development for 4-hydroxyphenylpyruvate dioxygenase, employing tyrosinemia 1 as a model for human diseases mediated by 2-oxoacid utilizing dioxygenases |
| EP1646377A4 (en) * | 2003-07-11 | 2009-09-09 | Merck & Co Inc | TREATMENT OF MOVEMENT DISORDERS WITH METABOTROPIC GLUTAMATE 4 RECEPTOR POSITIVE ALLOSTERIC MODULATOR |
| AU2006347397A1 (en) * | 2006-08-18 | 2008-02-21 | Syngenta Limited | Use of HPPD inhibitors in the treatment of depression and/or withdrawal symptoms associated with addictive drugs |
| US20100160295A1 (en) * | 2008-11-06 | 2010-06-24 | Synosia Therapeutics | Treatment of restless leg syndrome and sleep disorders |
-
2005
- 2005-02-28 GB GBGB0504103.3A patent/GB0504103D0/en not_active Ceased
-
2006
- 2006-02-27 PT PT06709910T patent/PT1853241E/pt unknown
- 2006-02-27 ES ES06709910T patent/ES2374761T3/es active Active
- 2006-02-27 AU AU2006217650A patent/AU2006217650B2/en not_active Ceased
- 2006-02-27 ZA ZA200707486A patent/ZA200707486B/xx unknown
- 2006-02-27 CA CA002598517A patent/CA2598517A1/en not_active Abandoned
- 2006-02-27 MX MX2007010480A patent/MX2007010480A/es not_active Application Discontinuation
- 2006-02-27 RU RU2007131934/15A patent/RU2420272C2/ru not_active IP Right Cessation
- 2006-02-27 DK DK06709910.1T patent/DK1853241T3/da active
- 2006-02-27 US US12/090,645 patent/US20090326072A1/en not_active Abandoned
- 2006-02-27 WO PCT/GB2006/000684 patent/WO2006090177A1/en not_active Ceased
- 2006-02-27 EP EP06709910A patent/EP1853241B1/en active Active
- 2006-02-27 JP JP2007557572A patent/JP2008531665A/ja active Pending
- 2006-02-27 BR BRPI0609177-6A patent/BRPI0609177A2/pt not_active IP Right Cessation
- 2006-02-27 AT AT06709910T patent/ATE524171T1/de active
- 2006-02-27 CN CN2006800133878A patent/CN101163466B/zh not_active Expired - Fee Related
-
2007
- 2007-08-21 IL IL185410A patent/IL185410A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0609177A2 (pt) | 2010-02-23 |
| ES2374761T3 (es) | 2012-02-21 |
| AU2006217650A1 (en) | 2006-08-31 |
| IL185410A0 (en) | 2008-08-07 |
| MX2007010480A (es) | 2008-02-07 |
| EP1853241B1 (en) | 2011-09-14 |
| PT1853241E (pt) | 2012-01-11 |
| AU2006217650B2 (en) | 2011-06-09 |
| CA2598517A1 (en) | 2006-08-31 |
| RU2420272C2 (ru) | 2011-06-10 |
| CN101163466A (zh) | 2008-04-16 |
| CN101163466B (zh) | 2011-12-07 |
| EP1853241A1 (en) | 2007-11-14 |
| JP2008531665A (ja) | 2008-08-14 |
| ZA200707486B (en) | 2009-02-25 |
| WO2006090177A1 (en) | 2006-08-31 |
| US20090326072A1 (en) | 2009-12-31 |
| DK1853241T3 (da) | 2012-01-16 |
| GB0504103D0 (en) | 2005-04-06 |
| HK1110211A1 (en) | 2008-07-11 |
| RU2007131934A (ru) | 2009-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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