ATE502947T1 - 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren - Google Patents

4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren

Info

Publication number
ATE502947T1
ATE502947T1 AT07847452T AT07847452T ATE502947T1 AT E502947 T1 ATE502947 T1 AT E502947T1 AT 07847452 T AT07847452 T AT 07847452T AT 07847452 T AT07847452 T AT 07847452T AT E502947 T1 ATE502947 T1 AT E502947T1
Authority
AT
Austria
Prior art keywords
cupyridine
modulators
derivatives
compounds
receptors
Prior art date
Application number
AT07847452T
Other languages
English (en)
Inventor
Li Chen
Wayne Wen Lai
Matthias Nettekoven
Olivier Roche
Deye Zheng
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE502947T1 publication Critical patent/ATE502947T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07847452T 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren ATE502947T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125721 2006-12-08
PCT/EP2007/062927 WO2008068173A1 (en) 2006-12-08 2007-11-28 4, 5, 6, 7-tetrahydro-thieno [3, 2-c] pyridine derivatives as h3 modulators

Publications (1)

Publication Number Publication Date
ATE502947T1 true ATE502947T1 (de) 2011-04-15

Family

ID=39156281

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07847452T ATE502947T1 (de) 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren

Country Status (8)

Country Link
US (1) US7557101B2 (de)
EP (1) EP2102214B1 (de)
JP (1) JP2010511656A (de)
CN (1) CN101547926A (de)
AT (1) ATE502947T1 (de)
CA (1) CA2670908A1 (de)
DE (1) DE602007013467D1 (de)
WO (1) WO2008068173A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE028435T2 (en) * 2010-09-02 2016-12-28 Suven Life Sciences Ltd Heterocyclic compounds as histamine H3 receptor ligands

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2495156A1 (fr) 1980-11-28 1982-06-04 Sanofi Sa Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique
FR2652579B1 (fr) 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
AU2007225273A1 (en) * 2006-03-10 2007-09-20 Neurogen Corporation Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues

Also Published As

Publication number Publication date
EP2102214A1 (de) 2009-09-23
CN101547926A (zh) 2009-09-30
JP2010511656A (ja) 2010-04-15
DE602007013467D1 (de) 2011-05-05
WO2008068173A9 (en) 2009-06-25
US20080146558A1 (en) 2008-06-19
WO2008068173A1 (en) 2008-06-12
US7557101B2 (en) 2009-07-07
CA2670908A1 (en) 2008-06-12
EP2102214B1 (de) 2011-03-23

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties