DE602007013467D1 - 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren - Google Patents

4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren

Info

Publication number
DE602007013467D1
DE602007013467D1 DE602007013467T DE602007013467T DE602007013467D1 DE 602007013467 D1 DE602007013467 D1 DE 602007013467D1 DE 602007013467 T DE602007013467 T DE 602007013467T DE 602007013467 T DE602007013467 T DE 602007013467T DE 602007013467 D1 DE602007013467 D1 DE 602007013467D1
Authority
DE
Germany
Prior art keywords
cypyridine
modulators
derivatives
compounds
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007013467T
Other languages
English (en)
Inventor
Li Chen
Wayne Wen Lai
Matthias Nettekoven
Olivier Roche
Deye Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602007013467D1 publication Critical patent/DE602007013467D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602007013467T 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren Active DE602007013467D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125721 2006-12-08
PCT/EP2007/062927 WO2008068173A1 (en) 2006-12-08 2007-11-28 4, 5, 6, 7-tetrahydro-thieno [3, 2-c] pyridine derivatives as h3 modulators

Publications (1)

Publication Number Publication Date
DE602007013467D1 true DE602007013467D1 (de) 2011-05-05

Family

ID=39156281

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007013467T Active DE602007013467D1 (de) 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä3,2-cüpyridinderivate als h3-modulatoren

Country Status (8)

Country Link
US (1) US7557101B2 (de)
EP (1) EP2102214B1 (de)
JP (1) JP2010511656A (de)
CN (1) CN101547926A (de)
AT (1) ATE502947T1 (de)
CA (1) CA2670908A1 (de)
DE (1) DE602007013467D1 (de)
WO (1) WO2008068173A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX354852B (es) * 2010-09-02 2018-03-22 Suven Life Sciences Ltd Star Compuestos de heterociclilo comoligandos del receptor h3 de la histamina.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2495156A1 (fr) 1980-11-28 1982-06-04 Sanofi Sa Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique
FR2652579B1 (fr) 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
ATE494782T1 (de) * 2006-03-10 2011-01-15 Neurogen Corp Piperazinyl-oxoalkyl-tetrahydroisochinoline und verwandte analoga

Also Published As

Publication number Publication date
US7557101B2 (en) 2009-07-07
CA2670908A1 (en) 2008-06-12
EP2102214A1 (de) 2009-09-23
CN101547926A (zh) 2009-09-30
WO2008068173A1 (en) 2008-06-12
US20080146558A1 (en) 2008-06-19
EP2102214B1 (de) 2011-03-23
WO2008068173A9 (en) 2009-06-25
JP2010511656A (ja) 2010-04-15
ATE502947T1 (de) 2011-04-15

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