PT1527100E - Anticorpos monoclonais humanos para interleucina-5 e métodos e composições compreendendo os mesmos - Google Patents
Anticorpos monoclonais humanos para interleucina-5 e métodos e composições compreendendo os mesmos Download PDFInfo
- Publication number
- PT1527100E PT1527100E PT03716836T PT03716836T PT1527100E PT 1527100 E PT1527100 E PT 1527100E PT 03716836 T PT03716836 T PT 03716836T PT 03716836 T PT03716836 T PT 03716836T PT 1527100 E PT1527100 E PT 1527100E
- Authority
- PT
- Portugal
- Prior art keywords
- antibodies
- methods
- relates
- compositions
- interleukin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 102000000743 Interleukin-5 Human genes 0.000 title abstract 3
- 108010002616 Interleukin-5 Proteins 0.000 title abstract 3
- 229940100602 interleukin-5 Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 108060003951 Immunoglobulin Proteins 0.000 abstract 2
- 238000001415 gene therapy Methods 0.000 abstract 2
- 102000018358 immunoglobulin Human genes 0.000 abstract 2
- 101000960969 Homo sapiens Interleukin-5 Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000055228 human IL5 Human genes 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Otolaryngology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36904402P | 2002-03-29 | 2002-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1527100E true PT1527100E (pt) | 2009-08-25 |
Family
ID=28791919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03716836T PT1527100E (pt) | 2002-03-29 | 2003-03-27 | Anticorpos monoclonais humanos para interleucina-5 e métodos e composições compreendendo os mesmos |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7141653B2 (de) |
| EP (1) | EP1527100B1 (de) |
| JP (2) | JP2005530490A (de) |
| CN (1) | CN1326879C (de) |
| AT (1) | ATE435239T1 (de) |
| AU (1) | AU2003220525A1 (de) |
| CA (1) | CA2479927C (de) |
| CY (1) | CY1109423T1 (de) |
| DE (1) | DE60328195D1 (de) |
| DK (1) | DK1527100T3 (de) |
| ES (1) | ES2327830T3 (de) |
| MX (1) | MXPA04009418A (de) |
| PT (1) | PT1527100E (de) |
| SI (1) | SI1527100T1 (de) |
| WO (1) | WO2003085089A2 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019120060A1 (zh) * | 2017-12-21 | 2019-06-27 | 三生国健药业(上海)股份有限公司 | 结合人il-5的单克隆抗体、其制备方法和用途 |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3672800A (en) | 1999-04-09 | 2000-11-14 | Kyowa Hakko Kogyo Co. Ltd. | Method for controlling the activity of immunologically functional molecule |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| PT1527100E (pt) * | 2002-03-29 | 2009-08-25 | Schering Corp | Anticorpos monoclonais humanos para interleucina-5 e métodos e composições compreendendo os mesmos |
| CA2505994A1 (en) | 2002-11-15 | 2004-06-03 | Chiron Corporation | Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis |
| AR046833A1 (es) * | 2003-11-10 | 2005-12-28 | Schering Corp | Anticuerpos anti-interleuquina-10 |
| PT2311873T (pt) | 2004-01-07 | 2018-11-20 | Novartis Vaccines & Diagnostics Inc | Anticorpo monoclonal específico para m-csf e respetivos usos |
| PL2070530T3 (pl) * | 2004-05-14 | 2016-06-30 | Merck Sharp & Dohme | Leczenie chorób związanych ze stosowaniem antybiotyków |
| JP4954709B2 (ja) * | 2004-10-28 | 2012-06-20 | 協和発酵キリン株式会社 | 子宮内膜症治療剤 |
| WO2006083390A2 (en) * | 2004-12-07 | 2006-08-10 | Children's Hospital Medical Center | Eotaxin-3 in eosinophilic esophagitis |
| JP5457671B2 (ja) * | 2005-07-28 | 2014-04-02 | ノバルティス アーゲー | M−csf特異的モノクローナル抗体およびその使用 |
| EP2277916A3 (de) * | 2005-07-28 | 2011-04-27 | Novartis AG | Verwendung von Antikörper zu M-CSF |
| WO2007035716A2 (en) | 2005-09-16 | 2007-03-29 | Raptor Pharmaceutical Inc. | Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof |
| DK3045182T3 (en) | 2005-11-14 | 2018-03-19 | Teva Pharmaceuticals Int Gmbh | ANTAGONIST ANTIBODIES AGAINST CALCITONIN GEN-RELATED PEPTIDE TO TREAT HEAT |
| JP2009519983A (ja) * | 2005-12-20 | 2009-05-21 | アラーナ・テラピューティクス・リミテッド | 部分的な新世界ザル結合領域を有するキメラ抗体 |
| WO2007087673A1 (en) | 2006-02-01 | 2007-08-09 | Arana Therapeutics Limited | Domain antibody construct |
| WO2007111661A2 (en) | 2006-03-20 | 2007-10-04 | Xoma Technology Ltd. | Human antibodies specific for gastrin materials and methods |
| US20080038258A1 (en) * | 2006-07-21 | 2008-02-14 | Amgen Inc. | Polypeptides with Reduced Susceptibility to Oxidation and Methods of Making |
| JP4842040B2 (ja) | 2006-07-25 | 2011-12-21 | 富士通株式会社 | 電子機器 |
| JP4781929B2 (ja) | 2006-07-25 | 2011-09-28 | 富士通株式会社 | 電子機器 |
| JP5148079B2 (ja) | 2006-07-25 | 2013-02-20 | 富士通株式会社 | 液冷ユニット用熱交換器および液冷ユニット並びに電子機器 |
| JP2008027370A (ja) | 2006-07-25 | 2008-02-07 | Fujitsu Ltd | 電子機器 |
| KR101437188B1 (ko) * | 2006-08-04 | 2014-10-02 | 노바르티스 아게 | Ephb3-특이적 항체 및 이의 용도 |
| EA201201533A1 (ru) | 2006-08-18 | 2014-11-28 | Новартис Аг | Prlr-специфическое антитело и его применения |
| WO2008036899A2 (en) * | 2006-09-22 | 2008-03-27 | Amgen Inc. | Methods for removing viral contaminants during protein purification |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| US7846434B2 (en) * | 2006-10-24 | 2010-12-07 | Trubion Pharmaceuticals, Inc. | Materials and methods for improved immunoglycoproteins |
| CN101646688A (zh) * | 2006-10-24 | 2010-02-10 | 特鲁比昂药品公司 | 利用栗精胺提高抗体依赖性细胞毒性的方法 |
| EA200900767A1 (ru) | 2006-12-07 | 2009-12-30 | Новартис Аг | Антагонистические антитела против ephb3 |
| US7695718B2 (en) | 2006-12-20 | 2010-04-13 | Xoma Technology Ltd. | Methods for the treatment of IL-1β related diseases |
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| JP5967861B2 (ja) | 2007-04-03 | 2016-08-10 | オキシレイン ユーケー リミテッド | 分子のグリコシル化 |
| HRP20140789T1 (hr) * | 2007-04-30 | 2014-10-10 | Glaxosmithkline Llc | Postupci primjene protutijela protiv il-5 |
| EP1997830A1 (de) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung |
| CN101802008B (zh) * | 2007-08-21 | 2015-04-01 | 安美基公司 | 人类c-fms抗原结合蛋白 |
| EP2205280B1 (de) * | 2007-09-27 | 2019-09-04 | Amgen Inc. | Pharmazeutische formulierungen |
| EP2219602A1 (de) | 2007-11-15 | 2010-08-25 | Amgen, Inc | Wässrige formulierung von mit antioxidantien stabilisiertem erythropoese-stimulierendem protein zur parenteralen verabreichung |
| HRP20141194T1 (hr) | 2007-12-20 | 2015-04-24 | Xoma (Us) Llc | Postupci lijeäśenja gihta |
| EP2803675A3 (de) | 2008-01-25 | 2014-12-24 | Amgen, Inc | Ferroportin-Antikörper und Anwendungsverfahren |
| WO2009109911A1 (en) | 2008-03-04 | 2009-09-11 | Pfizer Limited | Methods of treating chronic pain |
| KR20100134702A (ko) * | 2008-03-28 | 2010-12-23 | 글락소스미스클라인 엘엘씨 | 치료 방법 |
| CA2722600C (en) | 2008-05-01 | 2014-01-21 | Amgen Inc. | Anti-hepcidin antibodies and methods of use |
| US8128932B2 (en) * | 2009-08-17 | 2012-03-06 | Shanghai Aosaiersi Biotech Co., Ltd. | Anti-VEGFR monoclonal antibody, method of making and uses thereof |
| IN2012DN02521A (de) | 2009-08-28 | 2015-08-28 | Rinat Neuroscience Corp | |
| US8926976B2 (en) | 2009-09-25 | 2015-01-06 | Xoma Technology Ltd. | Modulators |
| EP3187877A1 (de) | 2009-09-25 | 2017-07-05 | XOMA Technology Ltd. | Screening-verfahren |
| ES2783024T3 (es) | 2009-09-29 | 2020-09-16 | Univ Gent | Hidrólisis de la unión de manosa-1-fosfo-6-manosa a fosfo-6-manosa |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| BR112012011980A2 (pt) | 2009-11-19 | 2021-09-08 | Oxyrane Uk Limited | Métodos de produzir células transformadas de yarrowia lipolytica e proteínas-alvocompreendendo n-glicanos, células transformadas de yarrowia lipolytica e suas culturas, bem como composição compreendendo glicoproteínas |
| BR112012018163A2 (pt) | 2010-01-21 | 2019-09-24 | Oxyrane Uk Ltd | métodos e composições para exibição de um polipeptídeo sobre a superfície de uma célula de levredura |
| JP6151183B2 (ja) | 2010-09-29 | 2017-06-21 | オキシレイン ユーケー リミテッド | マンノース−1−ホスホ−6−マンノース結合からキャップを外すことおよびリン酸化n−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法 |
| EP2622089B1 (de) | 2010-09-29 | 2023-11-01 | Oxyrane UK Limited | Demannosylierung von phosphorylierten n-glycanen |
| BR112013016235B1 (pt) * | 2010-12-22 | 2020-03-31 | Cephalon Australia Pty Ltd | Anticorpo isolado, uso de um anticorpo, ácido nucleico, célula transformada e composição farmacêutica |
| BR112013029951B1 (pt) | 2011-05-20 | 2020-10-20 | Alderbio Holdings Llc | composição farmacêutica e uso de anticorpos ou fragmentos de anticorpos anti-cgrp para tratar ou prevenir formas de diarreia crônicas e agudas |
| AU2012258980B8 (en) | 2011-05-20 | 2017-06-15 | H. Lundbeck A/S | Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers |
| TR201904088T4 (tr) | 2011-05-20 | 2019-05-21 | Alderbio Holdings Llc | Anti-CGRP bileşimleri ve bunların kullanımları. |
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| CA2840522A1 (en) | 2011-06-23 | 2012-12-27 | Children's Hospital Medical Center | Molecular diagnostic panel of eosinophilic gastrointestinal disorders |
| EP2794657B1 (de) | 2011-12-19 | 2017-10-11 | Xoma (Us) Llc | Verfahren zur behandlung von akne |
| IN2014CN04645A (de) * | 2012-01-31 | 2015-09-18 | Regeneron Pharma | |
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| RU2690675C2 (ru) | 2012-08-21 | 2019-06-05 | Санофи Байотекнолоджи | Способы лечения или предотвращения астмы посредством введения антагониста il-4r |
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| US20170114122A1 (en) | 2015-10-23 | 2017-04-27 | Alderbio Holdings Llc | Regulation of glucose metabolism using anti-cgrp antibodies |
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| WO2016141111A1 (en) | 2015-03-03 | 2016-09-09 | Xoma (Us) Llc | Treatment of post-prandial hyperinsulinemia and hypoglycemia after bariatric surgery |
| CN108251431B (zh) * | 2015-03-05 | 2020-12-08 | 北京百特美博生物科技有限公司 | 双载体系统及其用途 |
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- 2003-03-27 ES ES03716836T patent/ES2327830T3/es not_active Expired - Lifetime
- 2003-03-27 CN CNB038123975A patent/CN1326879C/zh not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2019120060A1 (zh) * | 2017-12-21 | 2019-06-27 | 三生国健药业(上海)股份有限公司 | 结合人il-5的单克隆抗体、其制备方法和用途 |
| US11370836B2 (en) | 2017-12-21 | 2022-06-28 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Monoclonal antibody binding to human IL-5, preparation method therefor and use thereof |
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| US20070025994A1 (en) | 2007-02-01 |
| AU2003220525A8 (en) | 2003-10-20 |
| SI1527100T1 (sl) | 2009-12-31 |
| EP1527100A4 (de) | 2006-06-14 |
| CN1326879C (zh) | 2007-07-18 |
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| WO2003085089A2 (en) | 2003-10-16 |
| CN1656122A (zh) | 2005-08-17 |
| CA2479927A1 (en) | 2003-10-16 |
| MXPA04009418A (es) | 2005-06-08 |
| HK1070907A1 (en) | 2005-06-30 |
| JP2010011874A (ja) | 2010-01-21 |
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| CA2479927C (en) | 2013-03-12 |
| CY1109423T1 (el) | 2014-08-13 |
| AU2003220525A1 (en) | 2003-10-20 |
| WO2003085089A3 (en) | 2005-03-10 |
| DK1527100T3 (da) | 2009-09-07 |
| ES2327830T3 (es) | 2009-11-04 |
| US20030194404A1 (en) | 2003-10-16 |
| DE60328195D1 (de) | 2009-08-13 |
| EP1527100B1 (de) | 2009-07-01 |
| EP1527100A2 (de) | 2005-05-04 |
| US7422742B2 (en) | 2008-09-09 |
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