PT1480634E - Moduladores selectivos do receptor do androgénio (sarms) para o tratamento da hiperplasia benigna da próstata - Google Patents

Moduladores selectivos do receptor do androgénio (sarms) para o tratamento da hiperplasia benigna da próstata Download PDF

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Publication number
PT1480634E
PT1480634E PT03737647T PT03737647T PT1480634E PT 1480634 E PT1480634 E PT 1480634E PT 03737647 T PT03737647 T PT 03737647T PT 03737647 T PT03737647 T PT 03737647T PT 1480634 E PT1480634 E PT 1480634E
Authority
PT
Portugal
Prior art keywords
androgen receptor
selective androgen
type
subject
benign prostate
Prior art date
Application number
PT03737647T
Other languages
English (en)
Portuguese (pt)
Inventor
Mitchell S Steiner
Karen A Veverka
Duane D Miller
James T Dalton
Kiwon Chung
Wenqing Gao
Original Assignee
Univ Tennessee Res Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tennessee Res Foundation filed Critical Univ Tennessee Res Foundation
Publication of PT1480634E publication Critical patent/PT1480634E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
PT03737647T 2002-02-07 2003-02-06 Moduladores selectivos do receptor do androgénio (sarms) para o tratamento da hiperplasia benigna da próstata PT1480634E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35430002P 2002-02-07 2002-02-07
US36299702P 2002-03-11 2002-03-11

Publications (1)

Publication Number Publication Date
PT1480634E true PT1480634E (pt) 2011-10-12

Family

ID=27737453

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03737647T PT1480634E (pt) 2002-02-07 2003-02-06 Moduladores selectivos do receptor do androgénio (sarms) para o tratamento da hiperplasia benigna da próstata

Country Status (20)

Country Link
US (2) US7776921B2 (https=)
EP (1) EP1480634B1 (https=)
JP (3) JP4677516B2 (https=)
KR (2) KR101032661B1 (https=)
CN (2) CN101732298B (https=)
AT (1) ATE518537T1 (https=)
AU (2) AU2003216174C1 (https=)
BR (1) BRPI0307699A2 (https=)
CA (2) CA2475108A1 (https=)
CY (1) CY1111917T1 (https=)
DK (1) DK1480634T3 (https=)
EA (2) EA013399B1 (https=)
GE (1) GEP20074122B (https=)
HR (2) HRP20100067A2 (https=)
IL (2) IL163380A (https=)
MX (1) MXPA04007639A (https=)
PT (1) PT1480634E (https=)
RS (1) RS69704A (https=)
TW (2) TW200918043A (https=)
WO (1) WO2003065992A2 (https=)

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US8445534B2 (en) 2000-08-24 2013-05-21 University Of Tennessee Research Foundation Treating androgen decline in aging male (ADAM)-associated conditions with SARMs
US7622503B2 (en) 2000-08-24 2009-11-24 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US8853266B2 (en) 2001-12-06 2014-10-07 University Of Tennessee Research Foundation Selective androgen receptor modulators for treating diabetes
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Publication number Publication date
JP2010209102A (ja) 2010-09-24
HRP20100067A2 (hr) 2010-04-30
RS69704A (sr) 2006-12-15
US8088828B2 (en) 2012-01-03
EA013399B1 (ru) 2010-04-30
AU2003216174C1 (en) 2010-01-28
HK1068103A1 (en) 2005-04-22
EA200401043A1 (ru) 2005-06-30
AU2003216174B2 (en) 2008-12-18
TWI374737B (en) 2012-10-21
CA2475108A1 (en) 2003-08-14
WO2003065992A3 (en) 2004-02-26
GEP20074122B (en) 2007-06-11
MXPA04007639A (es) 2005-07-13
AU2009201084A1 (en) 2009-04-09
EP1480634B1 (en) 2011-08-03
CN101732298A (zh) 2010-06-16
BRPI0307699A2 (pt) 2015-06-16
CN101732298B (zh) 2012-09-19
WO2003065992A2 (en) 2003-08-14
DK1480634T3 (da) 2011-11-14
TW200307537A (en) 2003-12-16
EA200901492A1 (ru) 2010-08-30
KR101032661B1 (ko) 2011-05-06
US20100280107A1 (en) 2010-11-04
US20040053897A1 (en) 2004-03-18
AU2003216174B8 (en) 2009-01-15
CA2689080C (en) 2011-07-05
KR20040089606A (ko) 2004-10-21
CN1646115A (zh) 2005-07-27
EP1480634A2 (en) 2004-12-01
IL163380A (en) 2010-06-30
JP2005522431A (ja) 2005-07-28
EP1480634A4 (en) 2008-01-16
TW200918043A (en) 2009-05-01
ATE518537T1 (de) 2011-08-15
JP4677516B2 (ja) 2011-04-27
US7776921B2 (en) 2010-08-17
JP2013144713A (ja) 2013-07-25
CY1111917T1 (el) 2015-11-04
CA2689080A1 (en) 2003-08-14
CN1646115B (zh) 2010-06-09
IL202675A (en) 2011-06-30
AU2003216174A1 (en) 2003-09-02
KR20100112659A (ko) 2010-10-19
HRP20040793A2 (en) 2006-10-31

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