MX2007007051A - Nuevos derivados de tiofenpirimidiona sustituida como inhibidores de la 17??-hidroxiesteroide deshidrogenasa. - Google Patents
Nuevos derivados de tiofenpirimidiona sustituida como inhibidores de la 17??-hidroxiesteroide deshidrogenasa.Info
- Publication number
- MX2007007051A MX2007007051A MX2007007051A MX2007007051A MX2007007051A MX 2007007051 A MX2007007051 A MX 2007007051A MX 2007007051 A MX2007007051 A MX 2007007051A MX 2007007051 A MX2007007051 A MX 2007007051A MX 2007007051 A MX2007007051 A MX 2007007051A
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxysteroid dehydrogenase
- inhibitors
- novel substituted
- thiophenepyrimidinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Esta invencion se refiere a nuevos derivados de tiofenpirimidinona sustituida y a su uso en terapia, especialmente para su uso en el tratamiento y/o prevencion de una enfermedad o trastorno dependiente de hormonas esteroides, tal como enfermedades o trastornos dependientes de hormonas esteroides que requieren la inhibicion de encimas 17??-hidroxiesteroide deshidogenasas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2004/053424 WO2006063615A1 (en) | 2004-12-13 | 2004-12-13 | NOVEL SUBSTITUTED THIOPHENEPYRIMIDINONE DERIVATIVES AS INHIBITORS OF 17β-HYDROXYSTEROID DEHYDROGENASE |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007007051A true MX2007007051A (es) | 2007-06-26 |
Family
ID=34959788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007007051A MX2007007051A (es) | 2004-12-13 | 2004-12-13 | Nuevos derivados de tiofenpirimidiona sustituida como inhibidores de la 17??-hidroxiesteroide deshidrogenasa. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1828197B1 (es) |
JP (1) | JP4686549B2 (es) |
CN (1) | CN101087793B (es) |
AT (1) | ATE431351T1 (es) |
AU (1) | AU2004325692B2 (es) |
BR (1) | BRPI0419229A (es) |
CA (1) | CA2590233A1 (es) |
DE (1) | DE602004021145D1 (es) |
ES (1) | ES2327240T3 (es) |
MX (1) | MX2007007051A (es) |
NO (1) | NO20073610L (es) |
PL (1) | PL1828197T3 (es) |
WO (1) | WO2006063615A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8080540B2 (en) | 2006-09-19 | 2011-12-20 | Abbott Products Gmbh | Therapeutically active triazoles and their use |
TW201520219A (zh) * | 2013-03-12 | 2015-06-01 | Lilly Co Eli | 咪唑並吡啶化合物 |
BR112016015578A2 (pt) | 2014-01-03 | 2017-08-08 | Elexopharm Gmbh | Inibidores de 17beta-hidroxiesteroide desidrogenases tipo 1 e tipo 2 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4054656A (en) * | 1975-09-10 | 1977-10-18 | Mead Johnson & Company | Thieno[2,3-d]pyrimidine antiallergic agents |
JPS62132884A (ja) * | 1985-12-05 | 1987-06-16 | Mitsubishi Chem Ind Ltd | 2−ベンジルチエノ〔2,3−d〕ピリミジン−4(3H)−オン誘導体 |
EP0364598A4 (en) * | 1988-03-02 | 1992-01-15 | Yoshitomi Pharmaceutical Industries, Ltd. | 3,4-dihydrothieno 2,3-d¨pyrimidine compounds and pharmaceutical application thereof |
US5597823A (en) * | 1995-01-27 | 1997-01-28 | Abbott Laboratories | Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrenergic antagonists |
FI20030393A (fi) * | 2003-03-14 | 2004-09-15 | Molekyyliendokrinologian Tutki | Menetelmiä, joilla voidaan ennustaa rintasyövän kehistyskulku ja yhdisteitä, joita voidaan käyttää sen ehkäisemiseksi tai hoitamiseksi |
US7754709B2 (en) * | 2003-06-10 | 2010-07-13 | Solvay Pharmaceuticals Bv | Tetracyclic thiophenepyrimidinone compounds as inhibitors of 17β hydroxysteroid dehydrogenase compounds |
US7465739B2 (en) * | 2003-06-10 | 2008-12-16 | Solvay Pharmaceuticals B.V. | Compounds and their use in therapy |
-
2004
- 2004-12-13 BR BRPI0419229-0A patent/BRPI0419229A/pt not_active IP Right Cessation
- 2004-12-13 DE DE602004021145T patent/DE602004021145D1/de active Active
- 2004-12-13 MX MX2007007051A patent/MX2007007051A/es active IP Right Grant
- 2004-12-13 CA CA002590233A patent/CA2590233A1/en not_active Abandoned
- 2004-12-13 AU AU2004325692A patent/AU2004325692B2/en not_active Expired - Fee Related
- 2004-12-13 EP EP04804787A patent/EP1828197B1/en active Active
- 2004-12-13 CN CN200480044596XA patent/CN101087793B/zh not_active Expired - Fee Related
- 2004-12-13 ES ES04804787T patent/ES2327240T3/es active Active
- 2004-12-13 AT AT04804787T patent/ATE431351T1/de not_active IP Right Cessation
- 2004-12-13 PL PL04804787T patent/PL1828197T3/pl unknown
- 2004-12-13 JP JP2007545846A patent/JP4686549B2/ja not_active Expired - Fee Related
- 2004-12-13 WO PCT/EP2004/053424 patent/WO2006063615A1/en active Application Filing
-
2007
- 2007-07-12 NO NO20073610A patent/NO20073610L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101087793A (zh) | 2007-12-12 |
EP1828197A1 (en) | 2007-09-05 |
BRPI0419229A (pt) | 2007-12-18 |
AU2004325692B2 (en) | 2012-01-19 |
JP2008523117A (ja) | 2008-07-03 |
ATE431351T1 (de) | 2009-05-15 |
CA2590233A1 (en) | 2006-06-22 |
EP1828197B1 (en) | 2009-05-13 |
AU2004325692A1 (en) | 2006-06-22 |
JP4686549B2 (ja) | 2011-05-25 |
WO2006063615A1 (en) | 2006-06-22 |
DE602004021145D1 (de) | 2009-06-25 |
PL1828197T3 (pl) | 2009-11-30 |
ES2327240T3 (es) | 2009-10-27 |
CN101087793B (zh) | 2011-09-07 |
NO20073610L (no) | 2007-09-12 |
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Legal Events
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FG | Grant or registration |