PT1311504E - Tetrazolil-fenil-acetamidas activadoras da glucoquinase - Google Patents

Tetrazolil-fenil-acetamidas activadoras da glucoquinase

Info

Publication number
PT1311504E
PT1311504E PT01962926T PT01962926T PT1311504E PT 1311504 E PT1311504 E PT 1311504E PT 01962926 T PT01962926 T PT 01962926T PT 01962926 T PT01962926 T PT 01962926T PT 1311504 E PT1311504 E PT 1311504E
Authority
PT
Portugal
Prior art keywords
tetrazolyl
activators
glucoquinase
phenyl acetamides
acetamides
Prior art date
Application number
PT01962926T
Other languages
English (en)
Inventor
Achyutharao Sidduri
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT1311504E publication Critical patent/PT1311504E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
PT01962926T 2000-08-15 2001-08-09 Tetrazolil-fenil-acetamidas activadoras da glucoquinase PT1311504E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22549400P 2000-08-15 2000-08-15

Publications (1)

Publication Number Publication Date
PT1311504E true PT1311504E (pt) 2005-10-31

Family

ID=22845106

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01962926T PT1311504E (pt) 2000-08-15 2001-08-09 Tetrazolil-fenil-acetamidas activadoras da glucoquinase

Country Status (20)

Country Link
US (3) US6369232B1 (pt)
EP (1) EP1311504B1 (pt)
JP (1) JP3961948B2 (pt)
KR (1) KR100518061B1 (pt)
CN (1) CN1209362C (pt)
AR (1) AR031718A1 (pt)
AT (1) ATE297921T1 (pt)
AU (2) AU8399801A (pt)
BR (1) BR0113312A (pt)
CA (1) CA2419416C (pt)
DE (1) DE60111540T2 (pt)
DK (1) DK1311504T3 (pt)
ES (1) ES2243541T3 (pt)
MX (1) MXPA03001275A (pt)
PA (1) PA8525201A1 (pt)
PE (1) PE20020386A1 (pt)
PT (1) PT1311504E (pt)
UY (1) UY26885A1 (pt)
WO (1) WO2002014312A1 (pt)
ZA (1) ZA200300904B (pt)

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SE0102299D0 (sv) 2001-06-26 2001-06-26 Astrazeneca Ab Compounds
SE0102764D0 (sv) 2001-08-17 2001-08-17 Astrazeneca Ab Compounds
US7078423B2 (en) * 2002-07-18 2006-07-18 Inotek Pharmaceuticals Corporation 5-Aryltetrazole compounds, compositions thereof, and uses therefor
US7087631B2 (en) * 2002-07-18 2006-08-08 Inotek Pharmaceuticals Corporation Aryltetrazole compounds, and compositions thereof
KR20050074959A (ko) * 2002-10-03 2005-07-19 노파르티스 아게 제ｉｉ형 당뇨병 치료에 유용한 글루코키나아제 활성인자로서의 치환된 (티아졸-２-일)-아미드 또는 술폰아미드
GB0226931D0 (en) 2002-11-19 2002-12-24 Astrazeneca Ab Chemical compounds
PE20040801A1 (es) 2002-12-12 2004-11-25 Hoffmann La Roche Derivados de pirazina y piridina 5-sustituidos como activadores de glucoquinasa
WO2004063194A1 (en) * 2003-01-06 2004-07-29 Eli Lilly And Company Heteroaryl compounds
PL378117A1 (pl) * 2003-02-11 2006-03-06 Prosidion Limited Tricyklopodstawione związki amidowe
JP4621198B2 (ja) * 2003-02-11 2011-01-26 プロシディオン・リミテッド トリ（シクロ）置換アミドグルコキナーゼ活性化化合物
PT1735322E (pt) * 2004-04-02 2012-01-12 Novartis Ag Derivados de sulfonamido-tiazolopiridina como activadores de glucoquinase úteis para o tratamento de diabetes de tipo 2
US7781451B2 (en) * 2004-04-02 2010-08-24 Novartis Ag Thiazolopyridine derivatives, pharmaceut ical conditions containing them and methods of treating glucokinase mediated conditions
WO2007007886A1 (en) * 2005-07-11 2007-01-18 Mitsubishi Tanabe Pharma Corporation An oxime derivative and preparations thereof
WO2007026761A1 (ja) 2005-08-31 2007-03-08 Astellas Pharma Inc. チアゾール誘導体
JP2007063225A (ja) * 2005-09-01 2007-03-15 Takeda Chem Ind Ltd イミダゾピリジン化合物
CA2624102A1 (en) 2005-09-29 2007-04-12 Sanofi-Aventis Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
GT200600428A (es) * 2005-09-30 2007-05-21 Compuestos organicos
GT200600429A (es) * 2005-09-30 2007-04-30 Compuestos organicos
WO2007051845A1 (en) * 2005-11-03 2007-05-10 Prosidion Ltd Tricyclo substituted amides
EP1948614A2 (en) * 2005-11-18 2008-07-30 Takeda San Diego, Inc. Glucokinase activators
EP1961746B1 (en) * 2005-12-15 2012-03-28 Nihon Nohyaku Co., Ltd. Phthalamide derivative, agricultural or horticultural pesticide, and use of the pesticide
US8034822B2 (en) 2006-03-08 2011-10-11 Takeda San Diego, Inc. Glucokinase activators
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US8008332B2 (en) 2006-05-31 2011-08-30 Takeda San Diego, Inc. Substituted indazoles as glucokinase activators
US7910747B2 (en) * 2006-07-06 2011-03-22 Bristol-Myers Squibb Company Phosphonate and phosphinate pyrazolylamide glucokinase activators
US7902248B2 (en) 2006-12-14 2011-03-08 Hoffmann-La Roche Inc. Oxime glucokinase activators
US8163779B2 (en) 2006-12-20 2012-04-24 Takeda San Diego, Inc. Glucokinase activators
TW200831081A (en) 2006-12-25 2008-08-01 Kyorin Seiyaku Kk Glucokinase activator
WO2008084872A1 (ja) 2007-01-10 2008-07-17 Mitsubishi Tanabe Pharma Corporation ヒドラゾン誘導体
KR20090121376A (ko) * 2007-03-07 2009-11-25 교린 세이야꾸 가부시키 가이샤 글루코키나아제 활성화 물질
US8173645B2 (en) * 2007-03-21 2012-05-08 Takeda San Diego, Inc. Glucokinase activators
ES2446932T3 (es) * 2007-10-08 2014-03-10 Advinus Therapeutics Private Limited Derivados de acetamida como activadores de glucoquinasa, su procedimiento y aplicaciones en medicina
CL2009000004A1 (es) * 2008-01-15 2010-02-19 Lilly Co Eli Forma cristalina de r-2-(4-ciclopropansulfonil-fenil)-n-pirazin-2-il-3-(tetrahidropiran-4-il)-propionamida; composicion farmaceutica que comprende a dicha forma cristalina; y uso para el tratamiento de diabetes o hiperglicemia.
CN101918363B (zh) * 2008-01-18 2012-09-05 安斯泰来制药株式会社 苯乙酰胺衍生物
NZ588462A (en) 2008-04-28 2012-07-27 Kyorin Seiyaku Kk Cyclopentylacrylic acid amide derivative
CN105176930B (zh) 2010-03-31 2021-05-04 斯克里普斯研究所 重编程细胞

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US3776917A (en) * 1972-06-05 1973-12-04 Schering Corp 2-amino-6-phenalkyl-aminopyridines and derivatives thereof
GB8909574D0 (en) 1989-04-26 1989-06-14 Ici Plc Chemical process
US5859052A (en) * 1993-01-14 1999-01-12 G. D. Searle & Co. Fatty acid analogs and prodrugs
US5468867A (en) * 1994-05-27 1995-11-21 Syntex (U.S.A.) Inc. Process for preparing1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl1-1H-indole-3-carboxylic acid
US5461049A (en) * 1994-05-27 1995-10-24 Warner-Lambert Company Amide tetrazole ACAT inhibitors
WO1998032753A1 (en) * 1997-01-28 1998-07-30 Merck & Co., Inc. THIAZOLE BENZENESULFONAMIDES AS β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
CA2368347C (en) * 1999-03-29 2007-05-22 F. Hoffmann-La Roche Ag Glucokinase activators

Also Published As

Publication number Publication date
DK1311504T3 (da) 2005-10-17
EP1311504B1 (en) 2005-06-15
DE60111540D1 (de) 2005-07-21
CN1466584A (zh) 2004-01-07
US20020035267A1 (en) 2002-03-21
MXPA03001275A (es) 2003-06-30
JP3961948B2 (ja) 2007-08-22
US20020035266A1 (en) 2002-03-21
CA2419416C (en) 2009-10-13
KR100518061B1 (ko) 2005-09-28
CA2419416A1 (en) 2002-02-21
ZA200300904B (en) 2004-04-30
PE20020386A1 (es) 2002-05-13
ES2243541T3 (es) 2005-12-01
US6388088B1 (en) 2002-05-14
EP1311504A1 (en) 2003-05-21
AU2001283998B2 (en) 2005-10-20
DE60111540T2 (de) 2006-03-16
UY26885A1 (es) 2002-02-28
US20020065275A1 (en) 2002-05-30
BR0113312A (pt) 2003-07-01
ATE297921T1 (de) 2005-07-15
US6369232B1 (en) 2002-04-09
CN1209362C (zh) 2005-07-06
AR031718A1 (es) 2003-10-01
US6441180B1 (en) 2002-08-27
KR20030022408A (ko) 2003-03-15
AU8399801A (en) 2002-02-25
PA8525201A1 (es) 2002-07-30
JP2004506632A (ja) 2004-03-04
WO2002014312A1 (en) 2002-02-21

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